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HOXC4

  • Official Full Name

    homeobox C4

  • Overview

    This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC4, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5 non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants that encode the same protein have been described for HOXC4. Transcript variant one includes the shared exon, and transcript variant two includes only gene-specific exons.
  • Synonyms

    HOXC4; homeobox C4; homeo box C4 , HOX3, HOX3E; homeobox protein Hox-C4; CP 19; CP19; Homeo box 3E; Homeo box C4; Homeo box protein HoxC4; Homeobox 3E; Homeobox protein CP19; Homeobox protein Hox C4; Homeobox protein Hox-3E; Homeobox protein HoxC4; Homeobox3E; HomeoboxC4; HOX 3; Hox 3E; HOX C4; HOX3; Hox3E; HOXC 4; HXC4_HUMAN; OTTHUMP00000217392; OTTHUMP00000217393;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HOXC4-28513TH Recombinant Human HOXC4 Wheat Germ N/A 105 amino acids
Human HOXC4-13905H Recombinant Human HOXC4, GST-tagged E.coli GST 1-264a.a.
Human HOXC4-4979H Recombinant Human HOXC4 Protein, GST-tagged Wheat Germ GST
Human HOXC4-5417HCL Recombinant Human HOXC4 293 Cell Lysate HEK293 N/A
Human HOXC4-3726HF Recombinant Full Length Human HOXC4 Protein, GST-tagged In Vitro Cell Free System GST 264 amino acids
Mouse HOXC4-7808M Recombinant Mouse HOXC4 Protein Mammalian Cell His
Mouse HOXC4-4292M Recombinant Mouse HOXC4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse HOXC4-4292M-B Recombinant Mouse HOXC4 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque HOXC4-2133R Recombinant Rhesus monkey HOXC4 Protein, His-tagged Mammalian Cell His
Rhesus Macaque HOXC4-1954R Recombinant Rhesus Macaque HOXC4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque HOXC4-1954R-B Recombinant Rhesus Macaque HOXC4 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HOXC4 Related Articles

HOXC4 involved in several pathways and played different roles in them. We selected most pathways HOXC4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HOXC4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

HOXC4 has several biochemical functions, for example, HMG box domain binding, protein binding, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HOXC4 itself. We selected most functions HOXC4 had, and list some proteins which have the same functions with HOXC4. You can find most of the proteins on our site.

Function Related Protein
HMG box domain bindingALX4;SP1;EGR2;PRRX1;POU3F3;JUN;HOXC4;GATA3;CEBPA
protein bindingTHOC2;CACYBP;SPG21;SBDS;TNFRSF11A;TLX1;CCNK;PPP1R3C;TMEM173
sequence-specific DNA bindingHSF5;ZFP110;SOX17;RREB1;HOXA2B;EOMES;UBP1;HLF;FOXG1A
transcription factor activity, sequence-specific DNA bindingMTA3;CREB1B;ZNF239;ASCL1B;RUNX1;TADA2B;BTBD8;HSFY1;SPZ1

HOXC4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HOXC4 here. Most of them are supplied by our site. Hope this information will be useful for your research of HOXC4.

SUV39H1; WHSC1L1; PRMT5; HTT; ELMOD2; PRMT6; RNF32

White, CA; Pone, EJ; et al. Histone Deacetylase Inhibitors Upregulate B Cell microRNAs That Silence AID and Blimp-1 Expression for Epigenetic Modulation of Antibody and Autoantibody Responses. JOURNAL OF IMMUNOLOGY 193:5933-5950(2014).
Zan, H; Casali, P; et al. Regulation of Aicda expression and AID activity. AUTOIMMUNITY 46:83-101(2013).
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