HSPA1L Protein, heat shock 70kDa protein 1-like

HSPA1L

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HSPA1L

Official Full Name heat shock 70kDa protein 1-like
Background This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein.
Synonyms HSPA1L; heat shock 70kDa protein 1-like; heat shock 70kD protein like 1; heat shock 70 kDa protein 1-like; HSP70 HOM; hum70t; heat shock 70 kDa protein 1L; heat shock 70kD protein-like 1; heat shock 10kDa protein 1-like; heat shock 70 kDa protein 1-Hom; H
    • Species :
    • Human
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HSPA1L-13985H Recombinant Human HSPA1L, GST-tagged E.coli GST
    Human HSPA1L-1452H Recombinant Human HSPA1L protein, His-tagged E.coli His
    Human HSPA1L-27084TH Recombinant Human HSPA1L Wheat Germ N/A
    Human HSPA1L-5103H Recombinant Human HSPA1L Protein, GST-tagged Wheat Germ GST
    Human HSPA1L-5356HCL Recombinant Human HSPA1L 293 Cell Lysate HEK293 N/A
    Rat Hspa1l-1453R Recombinant Rat Hspa1l protein, His-tagged E.coli His
    Rat HSPA1L-2945R Recombinant Rat HSPA1L Protein Mammalian Cell His

    HSPA1L involved in several pathways and played different roles in them. We selected most pathways HSPA1L participated on our site, such as Spliceosome, MAPK signaling pathway, Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with HSPA1L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Spliceosome SRSF7B; U2AF1L4; SNRPA; FAM120B; TRA2A; SF3A1; NHP2L1B; HNRPK; LSM3; PHF5A
    MAPK signaling pathway ARRB1; CACNA1H; PPP3R2; MAPKAPK3; RASA1; FGFR4; RRAS; CACNB2; Pdgfa&Pdgfb; RASA2
    Protein processing in endoplasmic reticulum PKZ; CAPN2B; SEC23B; DNAJC5G; DNAJA1; CUL1B; UBE2J1; HSPA6; DNAJC5GA; SEC61G
    Endocytosis VPS29; NEDD4L; RUFY1; SH3GL1A; MVB12BA; CCDC53; VPS45; ARRB2B; ASAP2A; RAB22A
    Antigen processing and presentation HLA-DQB1; KLRC4; KIR3DL2; HLA-C; KIR2DS2; HLA-F; HLA-DRA; PDIA3; HSPA1B; B2M
    Estrogen signaling pathway GNAI3; MMP2; KCNJ5; OPRM1; SHC4; HRAS; GRB2; HSPA2; RAF1; GRM1
    Legionellosis IL12A; EEF1G; MYD88; CASP1; HSPA1B; CD14; HSPA1A; RELA; CASP7; HSPA2
    Toxoplasmosis CASP8; TAB2; IFNGR1; IFNG; HSPA8; ITGA6; CASP9; AKT2; NOS2; BIRC7
    Measles TNFAIP3; SH2D1A; CD209A; TNFRSF10A; HSPA1L; cgr2b; STAT1; TLR4; NFKB1; IFNGR2
    Influenza A IFNA2; Fasl; ACTB; TLR4; OAS1B; LOC100033925; MAVS; IL12A; ADAR; HLA-DRA
    Epstein-Barr virus infection TRAF5; YWHAH; PSMD6; HDAC5; POLR1C; TRAF1; AKAP8L; CD58; FGR; SNW1

    HSPA1L has several biochemical functions, for example, ATP binding, heat shock protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HSPA1L itself. We selected most functions HSPA1L had, and list some proteins which have the same functions with HSPA1L. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding NSF; DDX23; PHKG1B; ACSM2; UBE2D1; UBE2E2; PAN3; PI4KA; CAMK2D2; KIF3CB
    heat shock protein binding TOMM34; PACRG; BAK1; HSPA6; DNAJC9; LMAN2; KCNJ11; BCOR; FKBP5; DNAJA4
    protein binding VAV3; SLC14A2; VTI1B; ING4; ZFP64; FKBP4; ATP6V1F; IRS4; ZNF695; COLGALT2
    ubiquitin protein ligase binding CUL5; UBXN1; PDE4D; FZD5; TRIB1; PRR5L; SMAD7; ATP6V0C; UBE2V1; ACTG1
    unfolded protein binding HSP90AA1.1; HSPA2; CLPXA; CCT3; TTC1; HTRA2; SSUH2.2; PFDN6; TRAP1; TOR1A

    HSPA1L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HSPA1L here. Most of them are supplied by our site. Hope this information will be useful for your research of HSPA1L.

    TP53; TRAF2; MAP3K1; TAB1; NFKB2; NFKBIE; IKBKB; MAP3K7; MAP3K7; RIPK2; TNFRSF1A; NFKB1; TNFRSF1B; NFKBIA; MAP3K8; YWHAZ

    Nishida, Y; Aida, K; et al. Antibody-Validated Proteins in Inflamed Islets of Fulminant Type 1 Diabetes Profiled by Laser-Capture Microdissection Followed by Mass Spectrometry. PLOS ONE 9:-(2014).
    Zhang, XM; Tanguay, RM; et al. Variants of HSPA1A in Combination with Plasma Hsp70 and Anti-Hsp70 Antibody Levels Associated with Higher Risk of Acute Coronary Syndrome. CARDIOLOGY 119:57-64(2011).

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