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IGFBP5

  • Official Full Name

    insulin-like growth factor binding protein 5

  • Overview

    Insulin-like growth factor-binding protein 5 is a protein that in humans is encoded by the IGFBP5 gene.
  • Synonyms

    IGFBP5; insulin-like growth factor binding protein 5; IBP5; insulin-like growth factor-binding protein 5; IBP-5; IGFBP-5; IGF-binding protein 5; Insulin-like growth factor-binding protein 5;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cell & Tissue Lysates
  • Canine
  • Cynomolgus
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Human Cell
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • yeast
  • C
  • hFc
  • His
  • His (Fc)
  • Avi
  • Myc
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IGFBP5-10H Active Recombinant Human IGFBP5 yeast N/A
Human IGFBP5-5052H Recombinant Human IGFBP5 protein E.coli N/A 252
Human IGFBP5-1629H Recombinant Human Insulin-Like Growth Factor Binding Protein 5 Mammalian cells N/A
Human IGFBP5-81H Recombinant Human Insulin-like Growth Factor Binding Protein 5 E.coli N/A
Human IGFBP5-11H Recombinant Human IGFBP5 protein, His-tagged HEK293 His
Human IGFBP5-7986H Recombinant Human IGFBP5 protein, His-tagged E.coli His Cys27~Gly248 (Accession # P24593)
Human IGFBP5-4430H Recombinant Human IGFBP5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human IGFBP5-361H Active Recombinant Human IGFBP5 Protein (Met1-Glu272), His-tagged Insect Cell His Met1-Glu272
Human IGFBP5-4430H-B Recombinant Human IGFBP5 Protein Pre-coupled Magnetic Beads HEK293
Human IGFBP5-2492H Recombinant Human IGFBP5 Protein (Leu21-Glu272), C-His tagged Mammalian cells C-His Leu21-Glu272
Human IGFBP5-4320H Recombinant Human IGFBP5 protein, His&Myc-tagged E.coli His&Myc 21-272aa
Mouse Igfbp5-5644M Active Recombinant Mouse Insulin-Like Growth Factor Binding Protein 5 Mammalian cells N/A
Mouse Igfbp5-2681M Recombinant Mouse Igfbp5 E.coli N/A
Mouse IGFBP5-8075M Recombinant Mouse IGFBP5 Protein Mammalian Cell His
Mouse Igfbp5-7987M Recombinant Mouse Igfbp5 protein, His-tagged E.coli His His25~Glu271 (Accession # Q07079)
Mouse Igfbp5-10572M Recombinant Mouse Igfbp5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Igfbp5-10572M-B Recombinant Mouse Igfbp5 Protein Pre-coupled Magnetic Beads HEK293
Rat Igfbp5-1416R Recombinant Rat Insulin-Like Growth Factor Binding Protein 5 E.coli N/A
Rat Igfbp5-7988R Recombinant Rat Igfbp5 protein, His-tagged E.coli His His25~Glu271 (Accession # P24594)
Rat IGFBP5-3010R Recombinant Rat IGFBP5 Protein Mammalian Cell His
Rat IGFBP5-2666R Recombinant Rat IGFBP5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat IGFBP5-2666R-B Recombinant Rat IGFBP5 Protein Pre-coupled Magnetic Beads HEK293
Canine IGFBP5-172C Recombinant Canine IGFBP5 protein(Met1-Glu271), hFc-tagged HEK293 C-hFc Met1-Glu271
Canine IGFBP5-001CCL Recombinant Canine IGFBP5 cell lysate Human Cell N/A
Cynomolgus IGFBP5-065C Active Recombinant Cynomolgus IGFBP5 protein, His-tagged HEK293 His Met1-Glu271
Cynomolgus Monkey IGFBP5-764CCL Recombinant Cynomolgus IGFBP5 cell lysate Human Cell N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • IGFBP5 Related Articles
  • IGFBP5 Related Research Area

IGFBP5 involved in several pathways and played different roles in them. We selected most pathways IGFBP5 participated on our site, such as Metabolism of proteins, Myometrial Relaxation and Contraction Pathways, Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs), which may be useful for your reference. Also, other proteins which involved in the same pathway with IGFBP5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Metabolism of proteinsGRP;ALG14;PDIA6;ADAMTS4;RAB27A;CST3;ADAMTSL5;SEC22C;SCMH1
Myometrial Relaxation and Contraction PathwaysPKIG;GABPA;CRCP;RGS20;IGFBP6;ATF5;CRH;IGFBP4;RGS16
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)PAPPA2;IGFBP5A;IGFBP4;IGF2B;KLK13;IGFBP1B;GZMH;IGFBP6A;IGFALS
Senescence and AutophagyMAP1LC3C;SLC39A2;SLC39A3;FKBP8;IGFBP5;LC3;MAP1LC3B;RSL1D1;RB1CC1

IGFBP5 has several biochemical functions, for example, fibronectin binding, insulin-like growth factor I binding, insulin-like growth factor II binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IGFBP5 itself. We selected most functions IGFBP5 had, and list some proteins which have the same functions with IGFBP5. You can find most of the proteins on our site.

Function Related Protein
fibronectin bindingCTGF;THBS1;CTSL1;ITGB1;SFRP2;IGFBP5;ITGAV;MMP13;LRRC15
insulin-like growth factor I bindingIGFBP2;IGFBP6A;IGFBP1A;IGFBP5A;IGFBP1B;INSR;IGFBP6;IGFBP5B;IGFBP6B
insulin-like growth factor II bindingIGFBP6A;IGFBP3;IGFBP2B;IGFBP2A;IGFBP1A;IGFBP5B;INSR;IGFBP6;IGFBP5
protein bindingCD200R1;P4HB;HOMEZ;HSP90AA1.2;SPANXD;TMEM67;TMEM79;MAP3K7IP3;FKBP1A

IGFBP5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IGFBP5 here. Most of them are supplied by our site. Hope this information will be useful for your research of IGFBP5.

BAG6; FHL1; PNO1

Pavlicek, A; Lira, ME; et al. Molecular Predictors of Sensitivity to the Insulin-like Growth Factor 1 Receptor Inhibitor Figitumumab (CP-751,871). MOLECULAR CANCER THERAPEUTICS 12:2929-2939(2013).
Ha, S; Iqbal, NJ; et al. Phosphorylation of the androgen receptor by PIM1 in hormone refractory prostate cancer. ONCOGENE 32:3992-4000(2013).
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