igfbp5
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  • Official Full Name
  • insulin-like growth factor binding protein 5
  • Background
  • Insulin-like growth factor-binding protein 5 is a protein that in humans is encoded by the IGFBP5 gene.
  • Synonyms
  • IGFBP5; insulin-like growth factor binding protein 5; IBP5; insulin-like growth factor-binding protein 5; IBP-5; IGFBP-5; IGF-binding protein 5; Insulin-like growth factor-binding protein 5;
Cat.#:IGFBP5-361HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human IGFBP5 Protein (Met1-Glu272), His-tagged
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Cat.#:IGFBP5-10HTag:N/A
Source (Host):YeastSpecies:Human
Product nameRecombinant Human IGFBP5
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Cat.#:IGFBP5-11HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human IGFBP5 protein, His-tagged
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Cat.#:IGFBP5-5052HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IGFBP5 protein
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Cat.#:IGFBP5-7986HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IGFBP5 protein, His-tagged
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Cat.#:Igfbp5-5644MTag:N/A
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Insulin-Like Growth Factor Binding Protein 5
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Cat.#:Igfbp5-7987MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Igfbp5 protein, His-tagged
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Cat.#:IGFBP5-8075MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse IGFBP5 Protein
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Cat.#:IGFBP5-3010RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat IGFBP5 Protein
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Cat.#:Igfbp5-7988RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Igfbp5 protein, His-tagged
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Cat.#:IGFBP5-172CTag:Fc
Source (Host):HEK293Species:Canine
Product nameRecombinant Canine IGFBP5, Fc-tagged
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Cat.#:IGFBP5-1629HTag:N/A
Source (Host):NS0Species:Human
Product nameRecombinant Human Insulin-Like Growth Factor Binding Protein 5
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Cat.#:IGFBP5-81HTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human Insulin-like Growth Factor Binding Protein 5
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Cat.#:Igfbp5-2681MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Igfbp5
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Cat.#:Igfbp5-1416RTag:N/A
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Insulin-Like Growth Factor Binding Protein 5
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Cat.#:IGFBP5-764CCLTag:
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus IGFBP5 cell lysate
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Cat.#:IGFBP5-001CCLTag:
Source (Host):HEK293Species:Canine
Product nameRecombinant Canine IGFBP5 cell lysate
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Involved Pathway

IGFBP5 involved in several pathways and played different roles in them. We selected most pathways IGFBP5 participated on our site, such as Metabolism of proteins, Myometrial Relaxation and Contraction Pathways, Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs), which may be useful for your reference. Also, other proteins which involved in the same pathway with IGFBP5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Metabolism of proteins
PAPPA2; CTAGE5; GALNT13; EEF1D; CDX2; FBXW4; ST8SIA3; CNIH2; TOMM20; DPH2
Myometrial Relaxation and Contraction Pathways
MYLK2; IGFBP4; PKIB; CRH; RGS4; CNN1; RGS20; ADM; ATF5; IGFBP6
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
IGFBP5A; KLK13; IGF2B; IGFBP6A; IGFBP5B; IGFBP6; PAPPA2; PAPPA; IGFBP5; IGFBP4
Senescence and Autophagy
GABARAP; ATG7; ING1; SLC39A1; RSL1D1; AMBRA1; IL24; ING2; FKBP8; RB1CC1

Protein Function

IGFBP5 has several biochemical functions, for example, fibronectin binding, insulin-like growth factor I binding, insulin-like growth factor II binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IGFBP5 itself. We selected most functions IGFBP5 had, and list some proteins which have the same functions with IGFBP5. You can find most of the proteins on our site.
Function
Related Protein
Function fibronectin binding
Related Protein MFAP2; IGFBP5A; FSTL3; IGFBP5B; CTSK; ITGB1A; LPA; IGFBP3; ITGB1; THBS1
Function insulin-like growth factor I binding
Related Protein IGFBP2A; IGFBP6; IGFBP6B; IGFBP3; IGFBP1A; IGFBP6A; IGFBP5B; IGFBP4; IGFBP2B; IGFBP5
Function insulin-like growth factor II binding
Related Protein IGFBP6B; IGFBP4; IGFBP3; INSR; IGFBP6; IGFBP1A; IGFBP2; IGFBP1B; IGFBP5A; IGFBP2A
Function protein binding
Related Protein ENG; FREM2; ZNF41; SF1; BCLAF1; SCG2; SSRP1; RXFP1; PBK; PRICKLE1

Interacting Protein

IGFBP5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IGFBP5 here. Most of them are supplied by our site. Hope this information will be useful for your research of IGFBP5.
BAG6; FHL1; PNO1

IGFBP5 Related Articles

Pavlicek, A; Lira, ME; et al. Molecular Predictors of Sensitivity to the Insulin-like Growth Factor 1 Receptor Inhibitor Figitumumab (CP-751,871). MOLECULAR CANCER THERAPEUTICS 12:2929-2939(2013).
Ha, S; Iqbal, NJ; et al. Phosphorylation of the androgen receptor by PIM1 in hormone refractory prostate cancer. ONCOGENE 32:3992-4000(2013).