• Official Full Name
  • Immunoglobulin heavy constant gamma 2 (G2m marker)
  • Background
  • Immunoglobulin G (IgG), is one of the most abundant proteins in human serum with normal levels between 8-17 mg/ml in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.
  • Synonyms
  • DKFZp686I04196; G2m marker; Ig gamma 2 chain C region; IGHG 2; IGHG2; Immunoglobulin heavy constant gamma 2; Immunoglobulin G 2; IgG2
Source (Host):HEK293Species:Human
Product nameRecombinant Human IGHG2 Protein

IGHG2 Related Articles

Jackson, KJL; Wang, Y; et al. Human immunoglobulin classes and subclasses show variability in VDJ gene mutation levels. IMMUNOLOGY AND CELL BIOLOGY 92:729-733(2014).
Butler, JE; Wertz, N; et al. Porcine IgG: structure, genetics, and evolution. IMMUNOGENETICS 61:209-230(2009).