• Official Full Name
  • IKBKB interacting protein
  • Background
  • IKK-β is an enzyme that serves as a protein subunit of IκB kinase, which is a component of the cytokine-activated intracellular signaling pathway involved in triggering immune responses. Its activity causes activation of a transcription factor known as Nuclear Transcription factor kappa-B or NF-κB. Activated IKK-β phosphorylates a protein called the inhibitor of NF-κB, IκB (IκBα), which binds NF-κB to inhibit its function. Phosphorylated IκB is degraded via the ubiquitination pathway, freeing NF-κB, and allowing its entry into the nucleus of the cell where it activates various genes involved in inflammation and other immune responses.
  • Synonyms
  • IKBIP; IKBKB interacting protein; inhibitor of nuclear factor kappa-B kinase-interacting protein; FLJ31051; I kappa B kinase interacting protein; IKIP; IKK interacting protein; IKK-interacting protein; IKBKB-interacting protein; i kappa-B kinase-interacti
Source (Host):HEK293Species:Human
Product nameRecombinant Human IKBIP Protein, MYC/DDK-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IKBIP protein, His & T7-tagged
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ikbip protein, His & T7-tagged
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Ikbip protein, His & T7-tagged
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat IKBIP Protein
Source (Host):Species:Human
Product nameRecombinant Human IKBIP 293 Cell Lysate

Protein Function

IKBIP has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IKBIP itself. We selected most functions IKBIP had, and list some proteins which have the same functions with IKBIP. You can find most of the proteins on our site.
Related Protein
Function protein binding
Related Protein CD274; ADNP; AURKA; SEMA4A; NQO1; PIF1; CSTF3; PLIN1; IL15; C17orf59

Interacting Protein

IKBIP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IKBIP here. Most of them are supplied by our site. Hope this information will be useful for your research of IKBIP.
MYOG; KRT15; NUP62; TPM3; C9orf16; TFIP11; Cep55; Ikbip

IKBIP Related Articles

Hennig, EE; Mikula, M; et al. Extracellular matrix and cytochrome P450 gene expression can distinguish steatohepatitis from steatosis in mice. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 18:1762-1772(2014).
Khattak, NA; Mir, A; et al. Computational Analysis of TRAPPC9: Candidate Gene for Autosomal Recessive Non-Syndromic Mental Retardation. CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS 13:699-711(2014).
Cen, H; Zhou, M; et al. Genetic interaction between genes involved in NF-kappa B signaling pathway in systemic lupus erythematosus. MOLECULAR IMMUNOLOGY 56:643-648(2013).