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IKBIP

  • Official Full Name

    IKBKB interacting protein

  • Overview

    IKK-β is an enzyme that serves as a protein subunit of IκB kinase, which is a component of the cytokine-activated intracellular signaling pathway involved in triggering immune responses. Its activity causes activation of a transcription factor known as Nuclear Transcription factor kappa-B or NF-κB. Activated IKK-β phosphorylates a protein called the inhibitor of NF-κB, IκB (IκBα), which binds NF-κB to inhibit its function. Phosphorylated IκB is degraded via the ubiquitination pathway, freeing NF-κB, and allowing its entry into the nucleus of the cell where it activates various genes involved in inflammation and other immune responses.
  • Synonyms

    IKBIP; IKBKB interacting protein; inhibitor of nuclear factor kappa-B kinase-interacting protein; FLJ31051; I kappa B kinase interacting protein; IKIP; IKK interacting protein; IKK-interacting protein; IKBKB-interacting protein; i kappa-B kinase-interacti;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IKBIP-512H Recombinant Human IKBIP Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human IKBIP-2008H Recombinant Human IKBIP protein, His & T7-tagged E.coli His/T7 Trp132~Gln314 (Accession # Q70UQ0)
Human IKBIP-5254HCL Recombinant Human IKBIP 293 Cell Lysate HEK293 N/A
Human IKBIP-3684H Recombinant Human IKBIP Protein (Trp132-Gln314), N-His tagged E.coli N-His Trp132-Gln314
Human IKBIP-5525H Recombinant Human IKBIP Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse Ikbip-2009M Recombinant Mouse Ikbip protein, His & T7-tagged E.coli His/T7 Thr78~Arg301 (Accession # Q9DBZ1)
Mouse Ikbip-3496M Recombinant Mouse Ikbip Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat IKBIP-3020R Recombinant Rat IKBIP Protein Mammalian Cell His
Rat Ikbip-2010R Recombinant Rat Ikbip protein, His & T7-tagged E.coli His/T7 Ser80~Ile315 (Accession # Q5EAJ6)
Rat IKBIP-2675R Recombinant Rat IKBIP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat IKBIP-2675R-B Recombinant Rat IKBIP Protein Pre-coupled Magnetic Beads HEK293
Bos taurus (Bovine) RFL36567BF Recombinant Full Length Bovine Inhibitor Of Nuclear Factor Kappa-B Kinase-Interacting Protein(Ikbip) Protein, His-Tagged E.coli expression system His Full Length (1-349)
Homo sapiens (Human) RFL8050HF Recombinant Full Length Human Inhibitor Of Nuclear Factor Kappa-B Kinase-Interacting Protein(Ikbip) Protein, His-Tagged E.coli expression system His Full Length (1-350)
Mus musculus (Mouse) RFL29640MF Recombinant Full Length Mouse Inhibitor Of Nuclear Factor Kappa-B Kinase-Interacting Protein(Ikbip) Protein, His-Tagged E.coli expression system His Full Length (1-373)
Rattus norvegicus (Rat) RFL4782RF Recombinant Full Length Rat Inhibitor Of Nuclear Factor Kappa-B Kinase-Interacting Protein(Ikbip) Protein, His-Tagged E.coli expression system His Full Length (1-373)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • IKBIP Related Articles

IKBIP involved in several pathways and played different roles in them. We selected most pathways IKBIP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IKBIP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

IKBIP has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IKBIP itself. We selected most functions IKBIP had, and list some proteins which have the same functions with IKBIP. You can find most of the proteins on our site.

Function Related Protein
protein bindingNR4A3;RPS13;TCEB3;CPEB3;C14orf93;CLEC7A;RHOG;RNF5;GSG1L

IKBIP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IKBIP here. Most of them are supplied by our site. Hope this information will be useful for your research of IKBIP.

MYOG; KRT15; NUP62; TPM3; C9orf16; TFIP11; Cep55; Ikbip

Hennig, EE; Mikula, M; et al. Extracellular matrix and cytochrome P450 gene expression can distinguish steatohepatitis from steatosis in mice. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 18:1762-1772(2014).
Khattak, NA; Mir, A; et al. Computational Analysis of TRAPPC9: Candidate Gene for Autosomal Recessive Non-Syndromic Mental Retardation. CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS 13:699-711(2014).
Cen, H; Zhou, M; et al. Genetic interaction between genes involved in NF-kappa B signaling pathway in systemic lupus erythematosus. MOLECULAR IMMUNOLOGY 56:643-648(2013).
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