• Official Full Name
  • integrator complex subunit 6
  • Background
  • DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3 end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). Three transcript variants encoding two different isoforms have been found for this gene.
  • Synonyms
  • INTS6; integrator complex subunit 6; DDX26, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 26; DBI 1; DDX26A; DICE1; HDB; INT6; Notchl2; DBI-1; DBI1; DDX26; DEAD box protein; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 26; Deleted in cancer 1; DKFZp434B105; INT6_HUMAN; INTS 6; OTTHUMP00000018439; OTTHUMP00000215034; OTTHUMP00000215036; Protein DDX26; Protein deleted in cancer 1; RNA helicase HDB; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human INTS6 Protein, GST-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human INTS6 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse INTS6 Protein
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish INTS6

Interacting Protein

INTS6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INTS6 here. Most of them are supplied by our site. Hope this information will be useful for your research of INTS6.

INTS6 Related Articles

Zhang, F; Ma, T; et al. A core hSSB1-INTS complex participates in the DNA damage response. JOURNAL OF CELL SCIENCE 126:4850-4855(2013).
Kapp, LD; Abrams, EW; et al. The Integrator Complex Subunit 6 (Ints6) Confines the Dorsal Organizer in Vertebrate Embryogenesis. PLOS GENETICS 9:-(2013).