Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

KLRC2

  • Official Full Name

    killer cell lectin-like receptor subfamily C, member 2

  • Overview

    Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined.
  • Synonyms

    KLRC2; killer cell lectin-like receptor subfamily C, member 2; NKG2-C type II integral membrane protein; CD159c; NKG2 C; NK cell receptor C; NKG2-C-activating NK receptor; CD159 antigen-like family member C; NKG2C; NKG2-C; MGC138244;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus
  • Homo sapiens (Human)
  • Human
  • Rhesus Macaque
  • E.coli
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • His|T7
  • N/A
  • N
  • hFc
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KLRC2-7062H Recombinant Human KLRC2 protein, His & T7-tagged E.coli His/T7 Arg19~Leu190 (Accession # P26717)
Human KLRC2-4895HCL Recombinant Human KLRC2 293 Cell Lysate HEK293 N/A
Human KLRC2-5900HF Recombinant Full Length Human KLRC2 Protein In Vitro Cell Free System amino acids
Human KLRC2-4914H Recombinant Human KLRC2 Protein Wheat Germ N/A
Human KLRC2-606H Recombinant Human KLRC2 Protein (94-231 aa), His-SUMO-tagged E.coli His/SUMO 94-231 aa
Human KLRC2-634H Recombinant Human KLRC2 protein, His-Avi-tagged HEK293 His-Avi It contains Glu98-Leu231
Human KLRC2-2244H Recombinant Human KLRC2 protein, His-tagged HEK293 His Ile94-Leu231
Human KLRC2-194H Recombinant Human KLRC2 and CD94 Protein, Glu98-Leu231 and Ser34-Ile179, N-His-Avi tagged, Biotinylated HEK293 N-His-Avi Glu98-Leu231 (NKG2C) and Ser34-Ile179 (CD94)
Human KLRC2-0578H Recombinant Human KLRC2 protein, His-tagged HEK293 His Ile94-Leu231
Human KLRC2-195H Recombinant Human KLRC2 Protein, Glu98-Leu231, N-His-Avi tagged, Biotinylated HEK293 N-His-Avi Glu98-Leu231
Human KLRC2-1323H Recombinant Human KLRC2 protein(Ile94- Leu231), hFc-tagged HEK293 N-hFc Ile94- Leu231
Cynomolgus KLRC2-0577C Recombinant Cynomolgus KLRC2 protein, His-tagged HEK293 His Ile94-Leu231
Homo sapiens (Human) RFL4726HF Recombinant Full Length Human Nkg2-C Type Ii Integral Membrane Protein(Klrc2) Protein, His-Tagged E.coli expression system His Full Length (1-231)
Rhesus Macaque KLRC2-2436R Recombinant Rhesus monkey KLRC2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque KLRC2-2257R Recombinant Rhesus Macaque KLRC2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque KLRC2-2257R-B Recombinant Rhesus Macaque KLRC2 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KLRC2 Related Research Area

KLRC2 involved in several pathways and played different roles in them. We selected most pathways KLRC2 participated on our site, such as Antigen processing and presentation, Natural killer cell mediated cytotoxicity, which may be useful for your reference. Also, other proteins which involved in the same pathway with KLRC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Antigen processing and presentationHLA-G;HLA-DRB5;HLA-DOB;HLA-B;HSPA1B;CALR;KIR2DS4;HLA-DRA;CTSB
Natural killer cell mediated cytotoxicityPIK3R2;KIR2DS4;PPP3R1;KLRD1;IFNA10;NFATC2;TYROBP;ITGB2;ICAM2

KLRC2 has several biochemical functions, for example, MHC class I protein complex binding, carbohydrate binding, protein antigen binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KLRC2 itself. We selected most functions KLRC2 had, and list some proteins which have the same functions with KLRC2. You can find most of the proteins on our site.

Function Related Protein
MHC class I protein complex bindingKLRD1;KLRC2;KLRC1
carbohydrate bindingCD209;CD33;ILLR1;LAYN;LGALS3;SBP;ASGR2;CLEC19A;NOMO1
protein antigen bindingKLRD1;H2-AB1;KLRC2;EP300;ITGA4
protein bindingABCA1;ARL4C;OTX1;DDX23;GDAP2;DNAJA4;NHLRC1;HUS1;SMC3
transmembrane signaling receptor activityIL4R.1;CD79A;CLDN4;GABRQ;FZD3A;FZD8A;OR4N4;GPR133;PTH1RB

KLRC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLRC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLRC2.

TYROBP; FBP1

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All KLRC2 Products

Required fields are marked with *

My Review for All KLRC2 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends