Recombinant Human KLRC2 and CD94 Protein, Glu98-Leu231 and Ser34-Ile179, N-His-Avi tagged, Biotinylated

• Cat.No.: KLRC2-194H
• Product Overview: Recombinant human NKG2C and CD94-N-His-Avi protein was developed from HEK293 and has a target region of N-His-Avi.

Specification

• Species: Human
• Source: HEK293
• Tag: Avi&His
• Protein Length: Glu98-Leu231 (NKG2C) and Ser34-Ile179 (CD94)
• Description: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined.
• Conjugation/Label: Biotin
• Form: Lyophilised
• Endotoxin: Endotoxin level was found to be less than 0.1 ng/μg (1 EU/μg).
• Notes: FOR RESEARCH USE ONLY (RUO).
• Storage: The lyophilized protein is stable for at least 1 year from date of receipt at -20 centigrade.
• Storage Buffer: Lyophilised from 0.2 μm filtered PBS solution pH 7.4. Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20 sec, 5K RPM
• Conjugation: Biotin

Gene Information

• Gene Name: KLRC2 killer cell lectin-like receptor subfamily C, member 2 [ Homo sapiens (human) ]
• Official Symbol: KLRC2
• Synonyms: KLRC2; killer cell lectin-like receptor subfamily C, member 2; NKG2-C type II integral membrane protein; CD159c; NKG2 C; NK cell receptor C; NKG2-C-activating NK receptor; CD159 antigen-like family member C; NKG2C; NKG2-C; MGC138244
• Gene ID: 3822
• mRNA Refseq: NM_002260
• Protein Refseq: NP_002251
• MIM: 602891
• UniProt ID: P26717