• Official Full Name
  • mitochondrial ribosomal protein L23
  • Background
  • Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. The gene is biallelically expressed, despite its location within a region of imprinted genes on chromosome 11.
  • Synonyms
  • MRPL23; mitochondrial ribosomal protein L23; RPL23L; 39S ribosomal protein L23, mitochondrial; L23MRP; L23 mitochondrial-related protein; L23mt; MRP-L23; Ribosomal protein L23-like; ribosomal protein related to L23 (mitochondrial); RPL23
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MRPL23 Protein, GST-tagged
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human MRPL23
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MRPL23, His-tagged
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat MRPL23 Protein
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey MRPL23 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken MRPL23
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish MRPL23
Source (Host):Species:Human
Product nameRecombinant Human MRPL23 293 Cell Lysate

Involved Pathway

MRPL23 involved in several pathways and played different roles in them. We selected most pathways MRPL23 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL23 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
RPS20; RPS15A; RPL34; RPL14; RPL10; RPL3; RPL4; MRPS18A; RPL26L1; RPL27A

Protein Function

MRPL23 has several biochemical functions, for example, RNA binding, nucleotide binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL23 itself. We selected most functions MRPL23 had, and list some proteins which have the same functions with MRPL23. You can find most of the proteins on our site.
Related Protein
Function RNA binding
Related Protein POP4; EXOSC1; PABPN1; CNP; DHX34; KHDC1C; XPO5; IGF2BP2A; RPL4; DDX51
Function nucleotide binding
Function protein binding
Related Protein KRTAP9-4; DYX1C1; PODXL2; UHRF2; PTK2B; GRIN1; GNA14; TBC1D1; LDHAL6B; NUMA1
Function structural constituent of ribosome
Related Protein MRPS31; RPL38; RPL17; RPS23; RPL32; RPS13; MRPS34; RPS28; FAUB; MRPL49

Interacting Protein

MRPL23 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL23 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL23.
PNMA1; 40038273; ATG12; C20orf24; USP44; NDUFAB1; ASB10; 2_aha_camp; JAK3; YBX1; Ccser2; MRPL50; MRPL9; Cd2ap

MRPL23 Related Articles

Kaur, J; Stuart, RA; et al. Truncation of the Mrp20 protein reveals new ribosome-assembly subcomplex in mitochondria. EMBO REPORTS 12:950-955(2011).
Haque, ME; Elmore, KB; et al. Properties of the C-terminal Tail of Human Mitochondrial Inner Membrane Protein Oxa1L and Its Interactions with Mammalian Mitochondrial Ribosomes. JOURNAL OF BIOLOGICAL CHEMISTRY 285:28353-28362(2010).