neurod1
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  • Official Full Name
  • neuronal differentiation 1
  • Background
  • NeuroD is a member of the basic helix-loop-helix (bHLH) family of transcription factors. These proteins function by forming heterodimers with E-proteins and binding to the canonical E-box sequence CANNTG. Neuronal activity results in CaMKII-mediated phosp
  • Synonyms
  • NEUROD1; neuronal differentiation 1; NEUROD, neurogenic differentiation 1; neurogenic differentiation factor 1; beta cell E box transactivator 2; BETA2; BHF 1; bHLHa3; MODY6; NeuroD; neurogenic helix loop helix protein NEUROD; beta-cell E-box transactiva
Cat.#:NEUROD1-1268HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NEUROD1, GST-tagged
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Cat.#:NEUROD1-224HTag:T7/His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NEUROD1 protein, T7/His-tagged
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Cat.#:NEUROD1-555HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human NEUROD1
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Cat.#:NEUROD1-3963RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat NEUROD1 Protein
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Cat.#:NEUROD1-6482CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken NEUROD1
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Cat.#:NEUROD1-8614ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish NEUROD1
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Cat.#:NEUROD1-3868HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human NEUROD1 293 Cell Lysate
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Involved Pathway

NEUROD1 involved in several pathways and played different roles in them. We selected most pathways NEUROD1 participated on our site, such as Maturity onset diabetes of the young, which may be useful for your reference. Also, other proteins which involved in the same pathway with NEUROD1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Maturity onset diabetes of the young
HNF1B; RFX6; SLC2A2; NR5A2; PDX1; ONECUT1; INS; FOXA3; HES1; INS2

Protein Function

NEUROD1 has several biochemical functions, for example, E-box binding, RNA polymerase II activating transcription factor binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NEUROD1 itself. We selected most functions NEUROD1 had, and list some proteins which have the same functions with NEUROD1. You can find most of the proteins on our site.
Function
Related Protein
Function E-box binding
Related Protein TFAP4; AHR; NEUROD1; MYC; TCF3; NEUROG1; MYOD1; SREBF2; ARNTL2; ASCL1
Function RNA polymerase II activating transcription factor binding
Related Protein BHLHE40; RB1; SMAD3; CREBBP; HEY2; CTNNB1; HNF4A; LDB1; NEUROD1; PITX2
Function RNA polymerase II core promoter proximal region sequence-specific DNA binding
Related Protein ZNF713; ASCL2; ZNF680; ZIC1; MLXIPL; PAX5; PITX3; EHF; EP300; MYC
Function RNA polymerase II transcription coactivator activity
Related Protein CITED4; SOX4; SMARCA2; CITED1; TRIM28; PHF17; PSIP1; CREBBP; MED12L; HYAL2
Function chromatin binding
Related Protein ASCL1; KDM8; SMAD6; POLR2B; GATA5; MEF2A; TRIM24; ERCC6; PCNA; CBX7
Function protein binding
Related Protein ZNF394; ZNF207; SPEF2; C17orf62; USO1; SRP14; KIAA1191; MKRN2; ZNF148; CCNK
Function protein heterodimerization activity
Related Protein TLR2; TYRO3; RAB3GAP2; SLC51B; TAF11; BCL2L2; BAX; USF1; HIST1H2AA; PBX1
Function contributes_to sequence-specific DNA binding
Related Protein HIF1A; EPAS1; SMAD4; TRIM28; PPARG; NEUROD1; HDAC4; FIGLA; HNRNPAB; ARNT
Function transcription coactivator activity
Related Protein MED7; NFE2; TADA1; ASXL1; CREBBP; ARL2BP; TFAP2B; NCOA4; WWTR1; NFKBIB
Function transcription factor activity, sequence-specific DNA binding
Related Protein PKNOX1; ELK1; ELK3; ASCL2; NFAT5A; VDRB; NKX6-2; RAI1; HSFY1; RORA
Function transcription factor binding
Related Protein ATOH8; SRY; Ar; TRERF1; LCOR; MYBBP1A; MAPK1; SP1; DIP2C; NKX2
Function transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
Related Protein HOXA10; NEUROG3; ZFAT; EPAS1; TFE3B; DLX3; HOXA7; EBF1; SOX11; GATA1

Interacting Protein

NEUROD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NEUROD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NEUROD1.
DUSP3

NEUROD1 Related Articles

Akazawa, N; Kawachi, H; et al. Neuroendocrine carcinoma of the esophagus: clinicopathologic study of 10 cases and verification of the diagnostic utility of mASH1, NeuroD1, and PGP9.5. ESOPHAGUS 11:245-257(2014).
Benitez, SG; Castro, AE; et al. Hypoxic Preconditioning Differentially Affects GABAergic and Glutamatergic Neuronal Cells in the Injured Cerebellum of the Neonatal Rat. PLOS ONE 9:-(2014).