NEUROD1

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NEUROD1

Official Full Name neuronal differentiation 1
Background NeuroD is a member of the basic helix-loop-helix (bHLH) family of transcription factors. These proteins function by forming heterodimers with E-proteins and binding to the canonical E-box sequence CANNTG. Neuronal activity results in CaMKII-mediated phosp
Synonyms NEUROD1; neuronal differentiation 1; NEUROD, neurogenic differentiation 1; neurogenic differentiation factor 1; beta cell E box transactivator 2; BETA2; BHF 1; bHLHa3; MODY6; NeuroD; neurogenic helix loop helix protein NEUROD; beta-cell E-box transactiva
    • Species :
    • Chicken
    • Human
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human NEUROD1-1268H Recombinant Human NEUROD1, GST-tagged E.coli GST
    Human NEUROD1-224H Recombinant Human NEUROD1 protein, T7/His-tagged E.coli T7/His
    Human NEUROD1-3868HCL Recombinant Human NEUROD1 293 Cell Lysate HEK293 N/A
    Human NEUROD1-555H Recombinant Human NEUROD1 Mammalian Cell His
    Rat NEUROD1-3963R Recombinant Rat NEUROD1 Protein Mammalian Cell His
    Chicken NEUROD1-6482C Recombinant Chicken NEUROD1 Mammalian Cell His
    Zebrafish NEUROD1-8614Z Recombinant Zebrafish NEUROD1 Mammalian Cell His

    NEUROD1 involved in several pathways and played different roles in them. We selected most pathways NEUROD1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with NEUROD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Maturity onset diabetes of the young MAFA; NEUROD1; FOXA2; FOXA3; NEUROG3; PAX4; INS; PKLR; HNF4G; NR5A2

    NEUROD1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by NEUROD1 itself. We selected most functions NEUROD1 had, and list some proteins which have the same functions with NEUROD1. You can find most of the proteins on our site.

    Function Related Protein
    E-box binding C1orf51; TAL1; ARNTL; NEUROD1; ASCL1; NEUROG1; NEUROD2; TCF3; ASCL2; BHLHE40
    RNA polymerase II activating transcription factor binding TBX20; ISL1; MAD2L2; BHLHE40; LDB1; NEUROD1; CREB1; SMAD3; HIPK2; EOMES
    RNA polymerase II core promoter proximal region sequence-specific DNA binding NOBOX; HLTF; MYBL2; SIX5; ETV2; MTF1; RFX6; NEUROD1; SIX1; ATF3
    RNA polymerase II transcription coactivator activity SOX11; PITX2; PRRX1; CITED2; NCOA1; SOX4; MKL1B; POU1F1; TBX20; SOX12
    chromatin binding CBX7; KAT2B; MED12; TTC5; PKN1; HMGB4; CRX; NFATC3; SUZ12; POU5F3
    protein binding INHBB; SORT1; FBXO34; DPH1; CCT7; TRP63; ZNF490; KCNE2; SNX32; CD27
    protein heterodimerization activity HIST1H4B; ADIPOR1; CA; HIST1H2AB; PAFAH1B2; HGF; TFAP2B; CHRNA5; CEBPB; CENPW
    contributes_to sequence-specific DNA binding EPAS1; ARNT; TCF3; HIF1A; SMAD4; HDAC4; PPARG; FIGLA; TRIM28; HNRNPAB
    transcription coactivator activity SERTAD2; PPARGC1A; MAML1; E4F1; CTBP2; MYOCD; ACTL6A; KAT2A; KAT6A; FHL5
    transcription factor activity, sequence-specific DNA binding ZFP27; TRPS1; ZKSCAN4; ZNF649; ZEB1; NFATC1; MEOX1; FOXD4; ZNF263; HIVEP2A
    transcription factor binding HMGA1; RELA; HDAC8; CEBPA; TFDP2; FOXA3; EPAS1; HMGB2; TAF1; RPS3
    transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding CARF; FOSL1; NR5A2; PAX5; MYBL1; ATOH1; TP53; MITF; CREB1; NR4A2

    NEUROD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NEUROD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NEUROD1.

    DUSP3

    Akazawa, N; Kawachi, H; et al. Neuroendocrine carcinoma of the esophagus: clinicopathologic study of 10 cases and verification of the diagnostic utility of mASH1, NeuroD1, and PGP9.5. ESOPHAGUS 11:245-257(2014).
    Benitez, SG; Castro, AE; et al. Hypoxic Preconditioning Differentially Affects GABAergic and Glutamatergic Neuronal Cells in the Injured Cerebellum of the Neonatal Rat. PLOS ONE 9:-(2014).

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