Recombinant Full Length Human NEUROD1 Protein, C-Flag-tagged
| Cat.No. : | NEUROD1-389HFL |
| Product Overview : | Recombinant Full Length Human NEUROD1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
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- Gene Information
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| Species : | Human |
| Source : | Mammalian Cells |
| Tag : | Flag |
| Description : | This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. |
| Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
| Molecular Mass : | 39.7 kDa |
| AA Sequence : | MTKSYSESGLMGEPQPQGPPSWTDECLSSQDEEHEADKKEDDLEAMNAEEDSLRNGGEEEDEDEDLEEEE EEEEEDDDQKPKRRGPKKKKMTKARLERFKLRRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKI ETLRLAKNYIWALSEILRSGKSPDLVSFVQTLCKGLSQPTTNLVAGCLQLNPRTFLPEQNQDMPPHLPTA SASFPVHPYSYQSPGLPSPPYGTMDSSHVFHVKPPPHAYSAALEPFFESPLTDCTSPSFDGPLSPPLSIN GNFSFKHEPSAEFEKNYAFTMHYPAATLAGAQSHGSIFSGTAAPRCEIPIDNIMSFDSHSHHERVMSAQL NAIFHDTRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
| Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Storage : | Store at -80 centigrade. |
| Concentration : | >50 ug/mL as determined by microplate BCA method. |
| Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Protein Families : | Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transcription Factors |
| Protein Pathways : | Maturity onset diabetes of the young |
| Full Length : | Full L. |
| Gene Name | NEUROD1 neuronal differentiation 1 [ Homo sapiens (human) ] |
| Official Symbol | NEUROD1 |
| Synonyms | T2D; BETA2; BHF-1; MODY6; NEUROD; bHLHa3 |
| Gene ID | 4760 |
| mRNA Refseq | NM_002500.5 |
| Protein Refseq | NP_002491.3 |
| MIM | 601724 |
| UniProt ID | Q13562 |
Not For Human Consumption!
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