Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, optic nerve, choroid, retina, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1).
OPTC has several biochemical functions, for example, extracellular matrix structural constituent. Some of the functions are cooperated with other proteins, some of the functions could acted by OPTC itself. We selected most functions OPTC had, and list some proteins which have the same functions with OPTC. You can find most of the proteins on our site.
Function extracellular matrix structural constituent
Related Protein COL11A1A; COL27A1A; COL27A1B; COL2A1B; TFPI2; TINAGL1; MFAP5; EFEMP2; COL4A4; ACAN
OPTC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OPTC here. Most of them are supplied by our site. Hope this information will be useful for your research of OPTC.