• Official Full Name
  • protocadherin gamma subfamily A, 2
  • Background
  • This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
  • Synonyms
  • PCDHGA2; protocadherin gamma subfamily A, 2; protocadherin gamma-A2; PCDH GAMMA A2; Protocadherin gamma A2; Protocadherin gamma subfamily A 2; OTTHUMP00000224529; PCDH-GAMMA-A2
Source (Host):HEK293Species:Human
Product nameRecombinant Human PCDHGA2 Protein, MYC/DDK-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PCDHGA2 protein, His & T7-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PCDHGA2, His-tagged
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PCDHGA2

Protein Function

PCDHGA2 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PCDHGA2 itself. We selected most functions PCDHGA2 had, and list some proteins which have the same functions with PCDHGA2. You can find most of the proteins on our site.
Related Protein
Function calcium ion binding
Related Protein SLIT1A; DSG2.1; SYT16; CIB3; PLCB1; CDK5R1; SYT2; CDH23; PCDH2AB8; EGF