• Official Full Name
  • pericentrin
  • Background
  • The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM). The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II.
  • Synonyms
  • PCNT; pericentrin; PCNT2, pericentrin 2 (kendrin); KEN; kendrin; KIAA0402; PCN; PCNTB; SCKL4; Seckel syndrome 4; pericentrin B; pericentrin-2; pericentrin-B; pericentrin-380; MOPD2; PCNT2; PCTN2
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PCNT protein, His & T7-tagged