• Official Full Name
  • proline, glutamate and leucine rich protein 1
  • Background
  • This gene encodes a transcription factor which coactivates transcription of estrogen receptor responsive genes and corepresses genes activated by other hormone receptors or sequence-specific transcription factors. Expression of this gene is regulated by both members of the estrogen receptor family. This gene may be involved in the progression of several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
  • Synonyms
  • PELP1; proline, glutamate and leucine rich protein 1; MNAR; P160; proline-, glutamic acid- and leucine-rich protein 1; transcription factor HMX3; proline and glutamic acid rich nuclear protein; modulator of non-genomic activity of estrogen receptor;
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PELP1 Protein
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PELP1 Protein
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PELP1 Protein, His-tagged

Protein Function

PELP1 has several biochemical functions, for example, chromatin binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PELP1 itself. We selected most functions PELP1 had, and list some proteins which have the same functions with PELP1. You can find most of the proteins on our site.
Related Protein
Function chromatin binding
Related Protein ATF5; SP110; SMAD2; LEF1; PHC1; HDGF2; TCF3; URI1; HDAC5; UPF1
Function poly(A) RNA binding
Related Protein MFAP1; DDX46; HELZ2; PPRC1; MKI67; RBM10; RPP25; UCHL5; DIDO1; ZCCHC24
Function protein binding
Related Protein DLL1; FAH; BACE1; ATP7B; ZNF544; ZFYVE1; KIR2DL1; EEF1E1; MRPL23; ASAP2
Function transcription factor binding
Related Protein HYAL1; SOX17; HDAC2; PYDC3; GATA4; MECP2; GTF2B; PBX1; EPAS1; NAB1

Interacting Protein

PELP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PELP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PELP1.
Nr4a1; Ywhae

PELP1 Related Articles

Dezen, S; Otonel, RAA; et al. Bovine viral diarrhea virus (BVDV) infection profile in a high production dairy herd with vaccination program against BVDV. PESQUISA VETERINARIA BRASILEIRA 33:141-147(2013).
Antoniassi, NAB; Pavarini, SP; et al. Clinical and pathological changes in sheep naturally infected with bluetongue virus in Rio Grande do Sul, Brazil.. PESQUISA VETERINARIA BRASILEIRA 30:1010-1016(2010).