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PEX2

  • Official Full Name

    peroxisomal biogenesis factor 2

  • Overview

    This gene encodes an integral peroxisomal membrane protein required for peroxisome biogenesis. The protein is thought to be involved in peroxisomal matrix protein import. Mutations in this gene result in one form of Zellweger syndrome and infantile Refsum disease. Alternative splicing results in multiple transcript variants encoding the same protein.
  • Synonyms

    PEX2; peroxisomal biogenesis factor 2; peroxisomal membrane protein 3 (35kD, Zellweger syndrome) , peroxisomal membrane protein 3, 35kDa , PXMP3; PAF 1; peroxin 2; PMP35; RNF72; Zellweger syndrome; ZWS3; 35 kDa peroxisomal membrane protein; PAF-1; PAF1; Peroxin-2; Peroxisomal membrane protein 3; peroxisomal membrane protein 3, 35kDa; Peroxisome assembly factor 1; Peroxisome biogenesis factor 2; PEX2_HUMAN; PMP3; PXMP3; RING finger protein 72; OTTHUMP00000226907; OTTHUMP00000226908; OTTHUMP00000226909; OTTHUMP00000226911; peroxisome assembly factor-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Dictyostelium discoideum (Slime mold)
  • Homo sapiens (Human)
  • Human
  • Komagataella pastoris (Yeast) (Pichia pastoris)
  • Mouse
  • Mus musculus (Mouse)
  • Podospora anserina (Pleurage anserina)
  • Rat
  • Rattus norvegicus (Rat)
  • Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
  • E.coli
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PEX2-2640H Recombinant Human PEX2 protein, His-tagged E.coli His Ala28~Glu118 (Accession # P28328)
Human PEX2-2641H Recombinant Human PEX2 protein, His & T7-tagged E.coli His/T7 Ser233~Leu305 (Accession # P28328)
Human PEX2-3288HCL Recombinant Human PEX2 293 Cell Lysate HEK293 N/A
Human PEX2-5053H Recombinant Human PEX2 Protein (Ala28-Glu118), His tagged E.coli His Ala28-Glu118
Mouse PEX2-12651M Recombinant Mouse PEX2 Protein Mammalian Cell His
Mouse PEX2-6648M-B Recombinant Mouse PEX2 Protein Pre-coupled Magnetic Beads HEK293
Mouse PEX2-6648M Recombinant Mouse PEX2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PEX2-4383R Recombinant Rat PEX2 Protein Mammalian Cell His
Rat PEX2-4043R Recombinant Rat PEX2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PEX2-4043R-B Recombinant Rat PEX2 Protein Pre-coupled Magnetic Beads HEK293
Dictyostelium discoideum (Slime mold) RFL2376DF Recombinant Full Length Dictyostelium Discoideum Peroxisome Biogenesis Factor 2(Pex2) Protein, His-Tagged E.coli expression system His Full Length (1-423)
Homo sapiens (Human) RFL1880HF Recombinant Full Length Human Peroxisome Biogenesis Factor 2(Pex2) Protein, His-Tagged E.coli expression system His Full Length (1-305)
Komagataella pastoris (Yeast) (Pichia pastoris) RFL31987KF Recombinant Full Length Pichia Pastoris Peroxisomal Biogenesis Factor 2(Pex2) Protein, His-Tagged E.coli expression system His Full Length (1-461)
Mus musculus (Mouse) RFL31262MF Recombinant Full Length Mouse Peroxisome Biogenesis Factor 2(Pex2) Protein, His-Tagged E.coli expression system His Full Length (1-305)
Podospora anserina (Pleurage anserina) RFL18838PF Recombinant Full Length Podospora Anserina Peroxisomal Biogenesis Factor 2(Pex2) Protein, His-Tagged E.coli expression system His Full Length (1-554)
Rattus norvegicus (Rat) RFL2487RF Recombinant Full Length Rat Peroxisome Biogenesis Factor 2(Pex2) Protein, His-Tagged E.coli expression system His Full Length (1-305)
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) RFL12267YF Recombinant Full Length Yarrowia Lipolytica Peroxisomal Biogenesis Factor 2(Pex2) Protein, His-Tagged E.coli expression system His Full Length (1-381)
Chicken PEX2-1832C Recombinant Chicken PEX2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PEX2 Related Articles

PEX2 involved in several pathways and played different roles in them. We selected most pathways PEX2 participated on our site, such as Peroxisome, which may be useful for your reference. Also, other proteins which involved in the same pathway with PEX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
PeroxisomeACOX2;ACSL1B;NOS2B;DHRS4;PXMP2;PEX13;ACOX1;PAOX;ABCD4

PEX2 has several biochemical functions, for example, protein binding, ubiquitin-protein transferase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PEX2 itself. We selected most functions PEX2 had, and list some proteins which have the same functions with PEX2. You can find most of the proteins on our site.

Function Related Protein
protein bindingPITX2;LRRC6;SF3B3;IMPA2;FRMD6;AKT1;STAT3;TNK1;TMEM139
ubiquitin-protein transferase activityRNF144AB;TRIM62;PAX6;MKRN1;FBXL14;CBL;MARCH8;UBE2T;WDSUB1
zinc ion bindingCDA;LIMK2;TRIM30A;TRIM46;TRIP6;CA13;ZNF8;CRYZL1;RNF144A

PEX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PEX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PEX2.

PEX19; TLE1; cirA2; C14orf1; cdkn1a_human_gene; PEX14; UBE2A; UBE2B; PEX5

Carrero-Lerida, J; Perez-Moreno, G; et al. Intracellular location of the early steps of the isoprenoid biosynthetic pathway in the trypanosomatids Leishmania major and Trypanosoma brucei. INTERNATIONAL JOURNAL FOR PARASITOLOGY 39:307-314(2009).
Shimozawa, N; Zhang, ZY; et al. Molecular mechanism of detectable catalase-containing particles, peroxisomes, in fibroblasts from a PEX2-defective patient. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 268:31-35(2000).
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