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PVRL3

  • Official Full Name

    poliovirus receptor-related 3

  • Overview

    Nectins originally identified as poliovirus receptor-related protein (PRR) are Ca2+-independent immunoglobulin-like cell-cell-adhesion molecules. Nectins comprise a family of four members: nectin-1 (CD111/PRR1), nectin-2 (CD112/PRR2), nectin-3 (CD113/PRR3
  • Synonyms

    PVRL3; poliovirus receptor-related 3; poliovirus receptor-related protein 3; CD113; CDw113; DKFZP566B0846; nectin 3; PPR3; PVRR3; PRR3; NECTIN-3; FLJ90624;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • Human Cell
  • Mammalian cells
  • Avi|Fc
  • C
  • His
  • Fc
  • His(C
  • ter)
  • His (Fc)
  • Avi
  • His|T7
  • human|IgG1|Fc
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PVRL3-692H Active Recombinant Human PVRL3 Protein, His-tagged Mammalian cells His Leu56-Asp400 & Gly58-Asp400
Human PVRL3-3275H Active Recombinant Human PVRL3 protein(Met1-Asp400), His-tagged HEK293 C-His Met1-Asp400
Human PVRL3-2186H Active Recombinant Human PVRL3 protein, His-tagged HEK293 His Gly 58 - Asp 400
Human PVRL3-2643HCL Recombinant Human PVRL3 cell lysate Human Cell N/A
Human PVRL3-2187H Active Recombinant Human PVRL3 Protein, Fc-Avi-tagged, Biotinylated HEK293 Avi/Fc
Human PVRL3-3953H Recombinant Human PVRL3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human PVRL3-3953H-B Recombinant Human PVRL3 Protein Pre-coupled Magnetic Beads HEK293
Human PVRL3-388H Recombinant Human PVRL3 protein, Fc-tagged HEK293 human/IgG1/Fc 343
Human PVRL3-277H Recombinant Human PVRL3 Protein (ECD), Fc-His-tagged(C-ter) HEK293 Fc-His(C-ter) Gly58-Asp400
Human PVRL3-0544H Active Recombinant Human PVRL3 protein, Fc-tagged HEK293 Fc Gly58-Asp400
Mouse PVRL3-13733M Recombinant Mouse Pvrl3 protein, His/T7-tagged E.coli His/T7
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PVRL3 Related Articles
  • PVRL3 Related Research Area

PVRL3 involved in several pathways and played different roles in them. We selected most pathways PVRL3 participated on our site, such as Cell adhesion molecules (CAMs), Adherens junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with PVRL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell adhesion molecules (CAMs)HLA-DOB;ITGA9;CLDN7;ESAM;HLA-A;CD8A;MHC1UEA;CLDN1;BMA2
Adherens junctionAASS;PTPRF;FYNB;RHOAD;WASLA;SSX2IPA;WASL;TCF7;TCF7L2

PVRL3 has several biochemical functions, for example, cell adhesion molecule binding, protein binding, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PVRL3 itself. We selected most functions PVRL3 had, and list some proteins which have the same functions with PVRL3. You can find most of the proteins on our site.

Function Related Protein
cell adhesion molecule bindingCADM4;PVRL3B;NRXN2;EZR;PVRL2L;POSTNB;CADM3;JUP;TENM2
protein bindingTBX1;TCHP;TACR3;GCA;CD93;HSPA1A;LAX1;MTCH1;TRIM32
protein homodimerization activityERN1;TCF12;TREX1;DPP4;BCL2A1A;DMRT1;SRM;PRPS1;MASP1
receptor activityPLXNA1;Pla2r1;PVRL3;DERL1;MRC1;TRAM1;CSF2RA;TLR3;CD2
receptor bindingNXPH3;NRTN;AGRP2;HAO1;SMARCD3;HFE2;GSTM7;NTF7;MBL2

PVRL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PVRL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PVRL3.

MLLT4; PVRL2; PVRL1; RGS20; KRTAP10-7; KRTAP10-8

Pang, J; Borjeson, TM; et al. Megaesophagus in a Line of Transgenic Rats: A Model of Achalasia. VETERINARY PATHOLOGY 51:1187-1200(2014).
Lachke, SA; Higgins, AW; et al. The cell adhesion gene PVRL3 is associated with congenital ocular defects. HUMAN GENETICS 131:235-250(2012).
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