Recombinant Human PVRL3 Protein (ECD), Fc-His-tagged(C-ter)

• Cat.No.: PVRL3-277H
• Product Overview: Recombinant Human PVRL3 Protein (ECD) with Fc-His tag (C-ter) was expressed in HEK293.

Specification

• Description: This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
• Source: HEK293
• Species: Human
• Tag: Fc-His(C-ter)
• Form: Powder
• Protein Length: Gly58-Asp400
• Endotoxin: Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test.
• Purity: > 97% (by SDS-PAGE)
• Applications: Binding, SDS-PAGE
• Notes: For laboratory research only, not for drug, diagnostic or other use.
• Storage: Lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C for up to one month, at 2-8°C for up to one week. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
• Storage Buffer: PBS (pH 7.4)
• Reconstitution: Reconstitute to a concentration of 0.1-0.5 mg/ml in sterile distilled water.

Gene Information

• Gene Name: PVRL3 poliovirus receptor-related 3 [ Homo sapiens ]
• Official Symbol: PVRL3
• Synonyms: PVRL3; poliovirus receptor-related 3; poliovirus receptor-related protein 3; CD113; CDw113; DKFZP566B0846; nectin 3; PPR3; PVRR3; PRR3; CDW113; NECTIN-3; FLJ90624; DKFZp566B0846
• Gene ID: 25945
• mRNA Refseq: NM_001243286
• Protein Refseq: NP_001230215
• MIM: 607147
• UniProt ID: Q9NQS3