• Official Full Name
  • RNA binding motif protein 14
  • Background
  • This gene encodes a ribonucleoprotein that functions as a general nuclear coactivator, and an RNA splicing modulator. This protein contains two RNA recognition motifs (RRM) at the N-terminus, and multiple hexapeptide repeat domain at the C-terminus that interacts with thyroid hormone receptor-binding protein (TRBP), and is required for transcription activation. Alternatively spliced transcript variants encoding different isoforms (with opposing effects on transcription) have been described for this gene.
  • Synonyms
  • RBM14; RNA binding motif protein 14; RNA-binding protein 14; COAA; coactivator activator; DKFZp779J0927; SIP; SYT interacting protein; SYTIP1; paraspeckle protein 2; SYT-interacting protein; transmembrane protein 137; synaptotagmin-interacting protein; RR
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RBM14, His-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse RBM14 Protein

Protein Function

RBM14 has several biochemical functions, for example, RNA binding, RNA polymerase II transcription cofactor activity, ligand-dependent nuclear receptor transcription coactivator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RBM14 itself. We selected most functions RBM14 had, and list some proteins which have the same functions with RBM14. You can find most of the proteins on our site.
Related Protein
Function RNA binding
Related Protein NUFIP1; KIAA0430; RPL7; FUS; PPARGC1A; DIS3; CNOT8; RBM8A; FBL; ZBP1
Function RNA polymerase II transcription cofactor activity
Related Protein CRSP7; MDT-19; MED13A; MED13B; NKX2-5; MED31; MED18; MED10; MED19; MED19B
Function ligand-dependent nuclear receptor transcription coactivator activity
Related Protein HMGA1; ZMIZ2; CARM1; HMGA1-RS1; NCOA2; CCDC62; FGF2; THRAP3; ZCCHC18; MED4
Function nucleotide binding
Related Protein LEMD3; UBE2KB; PUF60; RBFOX3; GNA15.1; TUBA8L4; ABCA4; ERBB3A; ACSL1; MYH1
Function poly(A) RNA binding
Related Protein RBM12B2; PHF5A; RPN1; HIST1H4F; DDX21; SRP54B; RPSA; EMG1; PSPC1; FBL
Function protein binding
Related Protein RNF43; TUBGCP4; TNFAIP8; MID1; C1QTNF8; BAG1; MPP7; STAP1; ANG; PRDM7
Function protein binding, bridging

Interacting Protein

RBM14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RBM14 here. Most of them are supplied by our site. Hope this information will be useful for your research of RBM14.
ESR1; ESR2; QKI; pre-let-7a

RBM14 Related Articles

Bhuvanakantham, R; Ng, ML; et al. West Nile virus and dengue virus capsid protein negates the antiviral activity of human Sec3 protein through the proteasome pathway. CELLULAR MICROBIOLOGY 15:1688-1706(2013).
Zan, H; Casali, P; et al. Regulation of Aicda expression and AID activity. AUTOIMMUNITY 46:83-101(2013).