Recombinant Human RBM14, His-tagged

• Cat.No.: RBM14-31045TH
• Product Overview: Recombinant full length protein, corresponding to amino acids 1-669 of Human RBM14 with N terminal His tag, 93kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-669 a.a.
• Description: This gene encodes a ribonucleoprotein that functions as a general nuclear coactivator, and an RNA splicing modulator. This protein contains two RNA recognition motifs (RRM) at the N-terminus, and multiple hexapeptide repeat domain at the C-terminus that interacts with thyroid hormone receptor-binding protein (TRBP), and is required for transcription activation. Alternatively spliced transcript variants encoding different isoforms (with opposing effects on transcription) have been described for this gene.
• Conjugation: HIS
• Form: Lyophilised:Reconstitute with 159 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFV HMRENAGALRAIEALHGHELRPGRALVVEMSRPRPLNT WKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAF VHMEKEADAKAAIAQLNGKEVKGKRINVELSTKGQKKGPG LAVQSGDKTKKPGAGDTAFPGTGGFSATFDYQQAFGNS TGGFDGQARQPTPPFFGRDRSPLRRSPPRASYVAPLTA QPATYRAQPSVSLGAAYRAQPSASLGVGYRTQPMTAQAAS YRAQPSVSLGAPYRGQLASPSSQSAAASSLGPYGGAQP SASALSSYGGQAAAASSLNSYGAQGSSLASYGNQPSSY GAQAASSYGVRAAASSYNTQGAASSLGSYGAQAASYGAQS AASSLAYGAQAASYNAQPSASYNAQSAPYAAQQAASYS SQPAAYVAQPATAAAYASQPAAYAAQATTPMAGSYGAQ PVVQTQLNSYGAQASMGLSGSYGAQSAAAATGSYGAAAAY GAQPSATLAAPYRTQSSASLAASYAAQQHPQAAASYRG QPGNAYDGAGQPSAAYLSMSQGAVANANSTPPPYERTR LSPPRASYDDPYKKAVAMSKRYGSDRRLAELSDYRRLSES QLSFRRSPTKSSLDYRRLPDAHSDYARYSGSYNDYLRA AQMHSGYQRRM
• Full Length: Full L.

Gene Information

• Gene Name: RBM14 RNA binding motif protein 14 [ Homo sapiens ]
• Official Symbol: RBM14
• Synonyms: RBM14; RNA binding motif protein 14; RNA-binding protein 14; COAA; coactivator activator; DKFZp779J0927; SIP; SYT interacting protein; SYTIP1
• Gene ID: 10432
• mRNA Refseq: NM_001198836
• Protein Refseq: NP_001185765
• MIM: 612409
• Uniprot ID: Q96PK6
• Chromosome Location: 11q13.2
• Function: RNA binding; RNA polymerase II transcription cofactor activity; ligand-dependent nuclear receptor transcription coactivator activity; nucleic acid binding; nucleotide binding