• Official Full Name
  • TCDD-inducible poly(ADP-ribose) polymerase
  • Background
  • This gene encodes a member of the poly(ADP-ribose) polymerase superfamily. Studies of the mouse ortholog have shown that the encoded protein catalyzes histone poly(ADP-ribosyl)ation and may be involved in T-cell function. Alternative splicing results in multiple transcript variants.
  • Synonyms
  • TIPARP; TCDD-inducible poly(ADP-ribose) polymerase; TCDD-inducible poly [ADP-ribose] polymerase; DDF1; DKFZP434J214; DKFZp686N0351; PARP 1; PARP 7; PARP7; pART14; RM1; poly [ADP-ribose] polymerase 7; FLJ40466; DKFZp686P1838
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human TIPARP Protein, GST-tagged
Source (Host):Species:Human
Product nameRecombinant Human TIPARP
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human TIPARP, GST-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TIPARP Protein
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish TIPARP

Protein Function

TIPARP has several biochemical functions, for example, NAD+ ADP-ribosyltransferase activity, enhancer binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TIPARP itself. We selected most functions TIPARP had, and list some proteins which have the same functions with TIPARP. You can find most of the proteins on our site.
Related Protein
Function NAD+ ADP-ribosyltransferase activity
Related Protein GIG2G; SIRT4; PARP2; GIG2Q; PARP6; GIG2F; ART3; CHAT1; PARP4; SIRT6
Function enhancer binding
Related Protein MESP1; SP1; TCF12; SMAD3; SMAD2; ELL3; SOX9; LEF1; RAI1; TCF3
Function metal ion binding
Related Protein ZFP143; RCV1; ASNA1; ZNFX1; TRIM43A; LMX1BB; GLIS1; ALOX5B.3; CYP46A1.2; ARMC1L

Interacting Protein

TIPARP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TIPARP here. Most of them are supplied by our site. Hope this information will be useful for your research of TIPARP.

TIPARP Related Articles

MacPherson, L; Ahmed, S; et al. Aryl Hydrocarbon Receptor Repressor and TiPARP (ARTD14) Use Similar, but also Distinct Mechanisms to Repress Aryl Hydrocarbon Receptor Signaling. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 15:7939-7957(2014).
Diani-Moore, S; Zhang, S; et al. Aryl Hydrocarbon Receptor Activation by Dioxin Targets Phosphoenolpyruvate Carboxykinase (PEPCK) for ADP-ribosylation via 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-inducible Poly(ADP-ribose) Polymerase (TiPARP). JOURNAL OF BIOLOGICAL CHEMISTRY 288:21514-21525(2013).