Recombinant Full Length Human TIPARP Protein, GST-tagged

• Cat.No.: TIPARP-6797HF
• Product Overview: Recombinant full-length Human TIPARP Protein is produced by Wheat Germ (in vitro) expression system. This protein is fused with a GST tag at the N-terminal.

Specification

• Description: The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 98.67 kDa
• Protein Length: 166 amino acids
• AA Sequence: MEMETTEPEPDCVVQPPSPPDDFSC QMRLSEKITPLKTCFKKKDQKRLGT GTLRSLRPILNTLLESGSLDGVFRS RNQSTDENSLHEPMMKKAMEINSSC PPAENNMSVLIPDRTNVGDQIPEAH PSTEAPERVVPIQDHSFPSETLSGT VADSTPAHFQTDLLHPVSSDVPTSP DCLDKVIDYVPGIFQENSFTIQYIL DTSDKLSTELFQDKSEEASLDLVFE LVNQLQYHTHQENGIEICMDFLQGT CIYGRDCLKHHTVLPYHWQIKRTTT QKWQSVFNDSQEHLERFYCNPENDR MRMKYGGQEFWADLNAMNVYETTEF DQLRRLSTPPSSNVNSIYHTVWKFF CRDHFGWREYPESVIRLIEEANSRG LKEVRFMMWNNHYILHNSFFRREIK RRPLFRSCFILLPYLQTLGGVPTQA PPPLEATSSSQIICPDGVTSANFYP ETWVYMHPSQDFIQVPVSAEDKSYR IIYNLFHKTVPEFKYRILQILRVQN QFLWEKYKRKKEYMNRKMFGRDRII NERHLFHGTSQDVVDGICKHNFDPR VCGKHATMFGQGSYFAKKASYSHNF SKKSSKGVHFMFLAKVLTGRYTMGS HGMRRPPPVNPGSVTSDLYDSCVDN FFEPQIFVIFNDDQSYPYFVIQYEE VSNTVSI
• Applications: Enzyme-linked Immunoabsorbent Assay;
  Western Blot (Recombinant protein);
  Antibody Production;
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: TIPARP TCDD-inducible poly(ADP-ribose) polymerase [ Homo sapiens ]
• Official Symbol: TIPARP
• Synonyms: TIPARP; DF1; DKFZP434J214; DKFZp686N0351; PARP 1; PARP 7; PARP7; pART14; RM1; FLJ40466; DKFZp434J214; DKFZp686P1838
• Gene ID: 25976
• mRNA Refseq: NM_001184717
• Protein Refseq: NP_001171646
• MIM: 612480
• UniProt ID: Q7Z3E1