• Official Full Name
  • ubiquitin specific peptidase 11
  • Background
  • Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional;activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and;deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that;specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating;enzyme which lies in a gene cluster on chromosome Xp11.23.
  • Synonyms
  • USP11; ubiquitin specific peptidase 11; ubiquitin specific protease 11; ubiquitin carboxyl-terminal hydrolase 11; UHX1; ubiquitin thioesterase 11; deubiquitinating enzyme 11; ubiquitin thiolesterase 11; ubiquitin-specific processing protease 11; ubiquitin
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human USP11 Protein, GST-tagged
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human USP11 protein, His-tagged

USP11 Related Articles

Kaasinen, E; Rahikkala, E; et al. Clinical characterization, genetic mapping and whole- genome sequence analysis of a novel autosomal recessive intellectual disability syndrome. EUROPEAN JOURNAL OF MEDICAL GENETICS 57:543-551(2014).
Burkhart, RA; Peng, Y; et al. Mitoxantrone Targets Human Ubiquitin-Specific Peptidase 11 (USP11) and Is a Potent Inhibitor of Pancreatic Cancer Cell Survival. MOLECULAR CANCER RESEARCH 11:901-911(2013).