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VPREB1

Official Full Name

pre-B lymphocyte 1
Overview

The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation.
Synonyms

VPREB1; pre-B lymphocyte 1; immunoglobulin iota chain; CD179A; VpreB; CD179 antigen like family member A; IGI; IGVPB; Pre B lymphocyte 1; Protein VPreB1; V(pre)B protein; VPREB 1; VpreB protein; OTTHUMP00000199011; OTTHUMP00000199012; CD179 antigen-like family member A;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

E.coli
HEK293
Mammalian Cell
Mammalian cells

Tag

C
His
His (Fc)
Avi
His|T7
SUMO
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	VPREB1-5648H	Recombinant Human VPREB1 protein, His & T7-tagged	E.coli	His/T7	Leu33~Met135 (Accession # P12018)	Inquiry
Human	VPREB1-0913H	Recombinant Human VPREB1 Protein (Leu33-Met135), N-His tagged	E.coli	N-His	Leu33-Met135	Inquiry
Human	VPREB1-3756H	Recombinant Human VPREB1 protein, His-SUMO-tagged	E.coli	His-SUMO	20-145aa	Inquiry
Human	VPREB1-5160H	Recombinant Human VPREB1 Protein (Met1-Pro145), C-His tagged	Mammalian cells	C-His	Met1-Pro145	Inquiry
Mouse	VPREB1-18355M	Recombinant Mouse VPREB1 Protein	Mammalian Cell	His		Inquiry
Mouse	Vpreb1-5649M	Recombinant Mouse Vpreb1 protein, His & T7-tagged	E.coli	His/T7	Leu43~Glu134 (Accession # P13372)	Inquiry
Mouse	VPREB1-10056M	Recombinant Mouse VPREB1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	VPREB1-10056M-B	Recombinant Mouse VPREB1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	Vpreb1-5650R	Recombinant Rat Vpreb1 protein, His & T7-tagged	E.coli	His/T7	Leu43~Met128 (Accession # D3Z922)	Inquiry

Involved Pathway
Protein Function
Interacting Protein
VPREB1 Related Articles

VPREB1 involved in several pathways and played different roles in them. We selected most pathways VPREB1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with VPREB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

VPREB1 has several biochemical functions, for example, protein binding, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by VPREB1 itself. We selected most functions VPREB1 had, and list some proteins which have the same functions with VPREB1. You can find most of the proteins on our site.

Function	Related Protein
protein binding	IARS;HSPBAP1;FSHB;RAB13;ACTN3;PIPOX;ROR2;ICAM4;CHP
receptor activity	ANTXR2;NOTCH2;NCR3;F2RL1.2;FPR1;CD5;NPC1;LRP1;PAQR3A

VPREB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VPREB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of VPREB1.

Dul, JL; Argon, Y; et al. The murine VpreB1 and VpreB2 genes both encode a protein of the surrogate light chain and are co-expressed during B cell development. EUROPEAN JOURNAL OF IMMUNOLOGY 26:906-913(1996).