Recombinant Human VPREB1 protein, His & T7-tagged

• Cat.No.: VPREB1-5648H
• Product Overview: Recombinant Human VPREB1 aa. (Leu33~Met135 (Accession # P12018)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Leu33~Met135
• Description: The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. Alternative splicing results in multiple transcript variants.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 15.9kDa
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 6.8.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: VPREB1 V-set pre-B cell surrogate light chain 1 [ Homo sapiens (human) ]
• Official Symbol: VPREB1
• Synonyms: VPREB1; V-set pre-B cell surrogate light chain 1; IGI; IGVPB; VPREB; CD179a; immunoglobulin iota chain; CD179 antigen-like family member A; pre-B lymphocyte 1; v(pre)B protein
• Gene ID: 7441
• mRNA Refseq: NM_007128.3
• Protein Refseq: NP_009059.1
• UniProt ID: P12018