VSX1
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Official Full Name
visual system homeobox 1
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Overview
The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy and keratoconus. Alternatively spliced transcript variants encoding different isoforms have been described. -
Synonyms
VSX1; visual system homeobox 1; posterior polymorphous corneal dystrophy , PPCD, visual system homeobox 1 homolog, CHX10 like (zebrafish); PPD; Homeodomain protein RINX; KTCN; Posterior polymorphous corneal dystrophy; PPCD; Retinal inner nuclear layer homeobox protein; RINX; Transcription factor VSX1; Visual system homeobox 1 homolog, CHX10 like; Visual system homeobox 1 homolog, CHX10 like (zebrafish); VSX1_HUMAN; OTTHUMP00000030468; OTTHUMP00000205188; OTTHUMP00000205189; OTTHUMP00000205192; KTCN1; CAASDS;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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| Human | VSX1-570H | Recombinant Human VSX1 Protein, MYC/DDK-tagged | HEK293 | Myc/DDK |
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| Human | VSX1-3188H | Recombinant Human VSX1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK |
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| Mouse | Vsx1-536M | Recombinant Mouse Vsx1 Protein, MYC/DDK-tagged | HEK293T | MYC/DDK |
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| Zebrafish | VSX1-8920Z | Recombinant Zebrafish VSX1 | Mammalian Cell | His |
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| Chicken | VSX1-6333C | Recombinant Chicken VSX1 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
VSX1 involved in several pathways and played different roles in them. We selected most pathways VSX1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with VSX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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VSX1 has several biochemical functions, for example, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VSX1 itself. We selected most functions VSX1 had, and list some proteins which have the same functions with VSX1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sequence-specific DNA binding | MSX2;TFCP2L1;ASCL1A;HOXB13A;LHX4;SHOX;FOXL2;CUX2;NR1H5 |
VSX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VSX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of VSX1.
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