ZGLP1
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Official Full Name
zinc finger, GATA-like protein 1
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Overview
Glucagon-like peptide-1 (GLP-1) formerly called insulinotropin, is a metabolic hormone derived from the transcription product of the proglucagon gene. GLP-1 is a physiologic mediator of satiety and regulates energy absorption and disposal. GLP-1 stimulate secretion of insulin in the presence of elevated blood glucose concentrations, but not during periods of low blood glucose concentrations (hypoglycemia). GLP-1 is a potent stimulator of insulin release in pancreas and has the ability to render pancreatic beta-cells glucose-competent. It has been used in the therapy of type 2 diabetes. -
Synonyms
GLP1; GLP-1;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- Human Cell
- Mammalian Cell
- His
- His (Fc)
- Avi
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | ZGLP1-941H | Recombinant Human Zinc Finger, GATA-like Protein 1 | E.coli | N/A | ||
Human | ZGLP1-167H | Recombinant Human Zinc Finger, GATA-Like Protein 1 | Human Cell | N/A | ||
Mouse | ZGLP1-19171M | Recombinant Mouse ZGLP1 Protein | Mammalian Cell | His | ||
Mouse | ZGLP1-10375M | Recombinant Mouse ZGLP1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | ZGLP1-10375M-B | Recombinant Mouse ZGLP1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Zebrafish | ZGLP1-4394Z | Recombinant Zebrafish ZGLP1 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
ZGLP1 involved in several pathways and played different roles in them. We selected most pathways ZGLP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ZGLP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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ZGLP1 has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding, RNA polymerase II transcription factor binding, chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZGLP1 itself. We selected most functions ZGLP1 had, and list some proteins which have the same functions with ZGLP1. You can find most of the proteins on our site.
Function | Related Protein |
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RNA polymerase II regulatory region sequence-specific DNA binding | NEUROD2;GFI1AA;PHOX2A;LMO2;ZFAT;MSX1;ZNF79;SOX13;PHOX2B |
RNA polymerase II transcription factor binding | MTA2;PITX2;GATA6;TBX6;TRP53;SFPI1;NFATC1;MKX;DHX9 |
chromatin binding | MED12;HDAC2;ATAD2B;TLE1;TOX3;MSL1A;KLF14;HMGB1;PRKAA2 |
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding | MYOCD;SOHLH2;NEUROD2;CSRNP1;GATA6;EAF2;PLAGL1;BARX2;GATA5 |
zinc ion binding | RNFT1;MT1B;LHX2;ZADH2;PRKCBP1L;NAPEPLD;BIRC2;RC3H2;RNF175 |
ZGLP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZGLP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZGLP1.
- Q&As
- Reviews
Q&As (6)
Ask a questionYes, the expression level of ZGLP1 protein may be affected by environmental factors such as nutritional status, inflammatory response, oxidative stress, etc. These factors may affect the expression of ZGLP1 protein by regulating gene transcription and translation levels.
ZGLP1 protein is mainly distributed in the liver, kidney, heart, skeletal muscle and other tissues of the human body.
Due to the important role of ZGLP1 protein in cell growth and differentiation, it may become an important target for drug discovery. Drugs targeting the ZGLP1 protein may have the potential to modulate cell growth and differentiation.
There is currently no way to directly increase the expression level or activity of ZGLP1 protein. However, its expression levels or activity can be affected by modulating the signal transduction pathways associated with it.
The current research on the expression level of ZGLP1 protein as a biomarker for disease diagnosis or prognosis is insufficient and needs to be further validated.
There are still some challenges and controversies in the current research on ZGLP1 protein, including its specific mechanism of action in different cell types and disease states, its interaction with other molecules, and the optimal treatment.
Customer Reviews (3)
Write a reviewThe results of multiple experiments are highly consistent and the reproducibility is particularly good.
Very good product, great for western-blot.
It can be dissolved in many types of reagents for easy handling.
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