Recombinant Human Zinc Finger, GATA-Like Protein 1

• Cat.No.: ZGLP1-167H
• Product Overview: Recombinant Human zinc finger, GATA-like protein 1 was expressed inhumanCells andThe sequence of the first five N-terminal amino acids was determined and was found to be His-Ala-Glu-Gly-Thr.

Specification

• Species: Human
• Source: Human Cells
• Tag: Non
• Description: Glucagon-like peptide-1 (GLP-1) formerly called insulinotropin, is a metabolic hormone derived from the transcription product of the proglucagon gene. GLP-1 is a physiologic mediator of satiety and regulates energy absorption and disposal. GLP-1 stimulate secretion of insulin in the presence of elevated blood glucose concentrations, but not during periods of low blood glucose concentrations (hypoglycemia). GLP-1 is a potent stimulator of insulin release in pancreas and has the ability to render pancreatic beta-cells glucose-competent. It has been used in the therapy of type 2 diabetes.
• Molecular Weight: The predicted molecular weight of Recombinant Human GLP-1 is 33 kD kDa.
• State Of Matter: Lyophilized.
• Formulation: Lyopohilized with no additives.
• Purity: >98% by SDS Page and HPLC.
• Endotoxin: <1.0 EU/µg as determined by the LAL method.
• Biological Activity: The biological activity of Human GLP-1 was determined by: 1. Regulates Glucose levels rapidly 2. Reduces Insulin resistence 3. Reduces Glucagon 4. Reduces HbA1c 5. Stimulates beta cell grwoth which stimulates insulin production.
• Storage: The lyophilized protein should be stored desiccated at -20℃. The reconstituted protein can be stored for at least one week at 4℃. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Gene Information

• Gene Name: ZGLP1 zinc finger, GATA-like protein 1 [ Homo sapiens ]
• Synonyms: ZGLP1; zinc finger, GATA-like protein 1; GLP1; GLP-1; FLJ39511; FLJ39703; GATA like protein 1
• Gene ID: 100125288
• mRNA Refseq: NM_001103167
• Protein Refseq: NP_001096637
• MIM: 611639
• UniProt ID: P0C6A0
• Chromosome Location: 19p13.2
• Function: metal ion binding; sequence-specific DNA binding; transcription factor activity; transcription repressor activity; zinc ion binding