| Cat. No. : |
ZGLP1-167H |
| Description : |
Glucagon-like peptide-1 (GLP-1) formerly called insulinotropin, is a metabolic hormone derived from the transcription product of the proglucagon gene. GLP-1 is a physiologic mediator of satiety and regulates energy absorption and disposal. GLP-1 stimulate secretion of insulin in the presence of elevated blood glucose concentrations, but not during periods of low blood glucose concentrations (hypoglycemia). GLP-1 is a potent stimulator of insulin release in pancreas and has the ability to render pancreatic beta-cells glucose-competent. It has been used in the therapy of type 2 diabetes. |
| Source : |
human cells. |
| Molecular Weight : |
The predicted molecular weight of Recombinant Human GLP-1 is 33 kD kDa. |
| State Of Matter : |
Lyophilized. |
| Formulation : |
Lyopohilized with no additives. |
| Purity : |
>98% by SDS Page and HPLC. |
| Endotoxin : |
<1.0 EU/µg as determined by the LAL method. |
| Biological Activity : |
The biological activity of Human GLP-1 was determined by: 1. Regulates Glucose levels rapidly 2. Reduces Insulin resistence 3. Reduces Glucagon 4. Reduces HbA1c 5. Stimulates beta cell grwoth which stimulates insulin production. |
| Storage : |
The lyophilized protein should be stored desiccated at -20℃. The reconstituted protein can be stored for at least one week at 4℃. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
