zmym2
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  • Official Full Name
  • zinc finger, MYM-type 2
  • Background
  • The protein encoded by this gene is a zinc finger protein that may act as a transcription factor. The encoded protein may be part of a BHC histone deacetylase complex. Translocation of this gene with the fibroblast growth factor receptor-1 gene (FGFR1) results in a fusion gene, which may be a cause of stem cell leukemia lymphoma syndrome (SCLL). Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]
  • Synonyms
  • ZMYM2; zinc finger, MYM-type 2; FIM; MYM; RAMP; SCLL; ZNF198; zinc finger MYM-type protein 2; zinc finger protein 198; fused in myeloproliferative disorders protein; rearranged in an atypical myeloproliferative disorder;
Cat.#:ZMYM2-19200MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ZMYM2 Protein
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Cat.#:ZMYM2-5299RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ZMYM2 Protein, His-tagged
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Involved Pathway

ZMYM2 involved in several pathways and played different roles in them. We selected most pathways ZMYM2 participated on our site, such as PluriNetWork, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZMYM2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
PluriNetWork
ZSCAN10; KLF5; XPO4; ZMYM2; RCOR2; ZFP57; IPO7; SALL3; SMARCC1; ZFP143

Protein Function

ZMYM2 has several biochemical functions, for example, metal ion binding, protein binding, ubiquitin conjugating enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZMYM2 itself. We selected most functions ZMYM2 had, and list some proteins which have the same functions with ZMYM2. You can find most of the proteins on our site.
Function
Related Protein
Function metal ion binding
Related Protein RNF180; NUDT12; ADH8B; ZBTB16A; PVALB3; CYP2V1; PDE10A; MT2; FBXO30A; CA15C
Function protein binding
Related Protein KMT2E; RNH1; TSC22D3; ELF2; CDK4; GPN3; CSF3R; FDX1L; CCDC6; JUB
Function ubiquitin conjugating enzyme binding
Related Protein RASD2; GRIK2; DCUN1D2; RNF144AA; ANKIB1A; DCUN1D4; TOLLIP; TRIM72; ZMYM2; TCHP
Function zinc ion binding
Related Protein SEC24C; TRIM35-36; NSMCE1; PIAS2; CSRP1B; ING3; CHMP1A; LHX5; MGRN1B; ESR2B

Interacting Protein

ZMYM2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZMYM2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZMYM2.
Nanog; Pou5f1

ZMYM2 Related Articles

Guzzo, CM; Ringel, A; et al. Characterization of the SUMO-Binding Activity of the Myeloproliferative and Mental Retardation (MYM)-Type Zinc Fingers in ZNF261 and ZNF198. PLOS ONE 9:-(2014).
Nam, SW; Park, KC; et al. Identification of Zinc Finger, MYM-type 2 (ZMYM2) as a regulator of sorafenib resistance in hepatocellular carcinoma cell lines. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY 29:633-639(2014).