AEBP1

  • Official Full Name

    AE binding protein 1

  • Overview

    The adipocyte enhancer binding protein 1 is a transcriptional repressor with carboxypeptidase (CP) activity. This protein binds to a regulatory sequence, adipocyte enhancer 1 (AE-1), located in the proximal promoter region of the adipose P2 (aP2) gene, which encodes the adipocyte fatty-acid binding protein. It is characterized as a member of the regulatory B-like CP family. This protein seems to be activated by a novel mechanism, whereby the direct binding of DNA enhances its protease activity. Adipocyte-enhancer binding protein 1 may play a role in differentiated vascular smooth muscle cells.
  • Synonyms

    AEBP1; AE binding protein 1; adipocyte enhancer-binding protein 1; ACLP; adipocyte enhancer binding protein 1; aortic carboxypeptidase like protein; AE-binding protein 1; aortic carboxypeptidase-like protein; FLJ33612;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Native Proteins
  • Human
  • Mouse
  • Rat
  • S.cerevisiae
  • E.coli
  • E.Coli or Yeast
  • HEK293
  • Mammalian Cell
  • S.cerevisiae
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • SUMO
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human AEBP1-394H Recombinant Human AEBP2 Protein, GST-tagged Wheat Germ GST
Mouse AEBP1-1393M Recombinant Mouse Aebp1 protein, His/sumo-tagged E.coli His/SUMO
Mouse Aebp1-4526M Recombinant Mouse Aebp1 protein, His-SUMO-tagged E.coli His-SUMO
Rat Aebp1-3196R Recombinant Rat Aebp1, His-tagged E.Coli or Yeast His
Rat AEBP1-550R Recombinant Rat AEBP1 Protein Mammalian Cell His
Rat AEBP1-206R-B Recombinant Rat AEBP1 Protein Pre-coupled Magnetic Beads HEK293
Rat AEBP1-206R Recombinant Rat AEBP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
S.cerevisiae AEBP1-8321S Native S. cerevisiae AEBP1 S.cerevisiae N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • AEBP1 Related Research Area

AEBP1 involved in several pathways and played different roles in them. We selected most pathways AEBP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AEBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

AEBP1 has several biochemical functions, for example, DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding, calmodulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AEBP1 itself. We selected most functions AEBP1 had, and list some proteins which have the same functions with AEBP1. You can find most of the proteins on our site.

Function Related Protein
DNA bindingSTAT1B;SUPV3L1;AIFM1;RORA;JUNBA;DMTF1;EGR2B;ZNF488;EGR4
RNA polymerase II regulatory region sequence-specific DNA bindingE2F7;HOXD8;ZSCAN2;NFKB1;RXRB;BARX2;DLX2;KLF12;ATF4B1
calmodulin bindingKCNQ3;ITPKB;CAMSAP1L1;MYH10;PHKA1;CAMK4;DAPK1;PPP3CC;CALD1
carboxypeptidase activityCNDP1;ACE;CPM;CPD;NAALAD2;AGBL4;CTSA;ACE2;CPA2
metallocarboxypeptidase activityCPA6;AGBL1;CPA5;CPDB;AGBL2;CPA1;CPM;CPA3;AGTPBP1
transcription corepressor activityPSMC3;CIR1;SMYD1;CCAR1;ID4;AEBP2;NR1H4;ALX1;RBFOX2
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific bindingETV3;MSX2;BCL6;FOXD3;ARHGAP35;HOXD9;E4F1;CGGBP1;ASCL3
zinc ion bindingPRDM2;PHF23A;SEC24C;Adamts19;MMP10;MICALL2;AQPEP;TRAF4A;KDM5A

AEBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AEBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AEBP1.

  • Q&As
  • Reviews

Q&As (10)

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Are there any specific structural features or domains of Aebp1 protein that are critical for its function or interaction with other molecules? 01/06/2023

The structural features or domains of Aebp1 protein, including the DNA-binding domain and regions involved in protein-protein interactions, are critical for its function and interaction with other molecules in cellular processes.

What are the tissue-specific expression patterns of Aebp1 protein and the factors that regulate its expression levels? 09/17/2022

The tissue-specific expression patterns of Aebp1 protein vary across different organs and cell types. Factors regulating its expression levels include transcriptional control and signaling pathways.

Are there any known post-translational modifications or regulatory factors that modulate the activity or stability of Aebp1 protein? 07/13/2021

Post-translational modifications, such as phosphorylation or acetylation, and regulatory factors modulate the activity or stability of Aebp1 protein, impacting its function and cellular responses.

Are there any genetic variations or mutations in the Aebp1 gene that impact the expression or function of Aebp1 protein? 06/28/2021

Genetic variations or mutations in the Aebp1 gene may impact the expression or function of Aebp1 protein, potentially contributing to altered cellular processes and disease susceptibility.

How does dysregulation or dysfunction of Aebp1 protein affect cellular functions or contribute to disease development? 12/28/2018

Dysregulation or dysfunction of Aebp1 protein can disrupt cellular processes, such as adipogenesis or glucose metabolism, and contribute to the development of metabolic disorders or obesity-related diseases.

Does Aebp1 protein interact with other proteins or participate in protein complexes, and if so, what are the functional implications? 07/08/2018

Aebp1 protein interacts with other proteins, such as transcription factors or co-regulators, forming protein complexes that influence gene expression and cellular processes.

Does Aebp1 protein have DNA-binding activity, and if so, what are the target DNA sequences or specific binding motifs? 06/23/2017

Aebp1 protein exhibits DNA-binding activity, recognizing specific DNA sequences or binding motifs that regulate the expression of target genes involved in adipocyte differentiation and metabolic regulation.

How is the subcellular localization of Aebp1 protein determined, and are there specific mechanisms or targeting sequences involved? 01/19/2017

The subcellular localization of Aebp1 protein is determined by specific mechanisms and targeting sequences, which facilitate its transport and localization to specific cellular compartments.

What experimental techniques have been employed to investigate the functional significance of Aebp1 protein? 12/18/2016

Experimental techniques such as gene expression analysis, chromatin immunoprecipitation, knockdown or overexpression studies, and functional assays have been employed to investigate the functional significance of Aebp1 protein.

What is the molecular function or role of Aebp1 protein in specific cellular processes or molecular pathways? 02/27/2015

Aebp1 protein plays a role in various cellular processes, including adipogenesis, glucose metabolism, and cell differentiation, by regulating target gene expression and interacting with signaling pathways.

Customer Reviews (3)

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Reviews
07/25/2022

    Characterizing protein-protein interactions involved in immune checkpoint regulation.

    03/05/2019

      Exploring protein-protein interactions involved in cell cycle checkpoints.

      01/10/2018

        Determining protein-protein interaction interfaces using isothermal titration calorimetry.

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