AHSA1

  • Official Full Name

    AHA1, activator of heat shock 90kDa protein ATPase homolog 1

  • Overview

    Activator of 90 kDa heat shock protein ATPase homolog 1 is an enzyme that in humans is encoded by the AHSA1 gene.
  • Synonyms

    AHSA1; AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast); C14orf3, chromosome 14 open reading frame 3; activator of 90 kDa heat shock protein ATPase homolog 1; p38; AHA1; C14orf3;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human AHSA1-26659TH Recombinant Human AHSA1 E.coli N/A
Human AHSA1-9499H Recombinant Human AHSA1, GST-tagged E.coli GST 1-338a.a.
Human AHSA1-322H Recombinant Human AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) E.coli N/A
Human AHSA1-26661TH Recombinant Human AHSA1, His-tagged E.coli His
Human AHSA1-467H Recombinant Human AHSA1 Protein, GST-tagged Wheat Germ GST
Human AHSA1-499H Recombinant Human AHSA1, His-tagged E.coli His
Human AHSA1-8961HCL Recombinant Human AHSA1 293 Cell Lysate HEK293 N/A
Human AHSA1-2443H Recombinant Human AHSA1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human AHSA1-1006HF Recombinant Full Length Human AHSA1 Protein, GST-tagged In Vitro Cell Free System GST 338 amino acids
Mouse Ahsa1-29M Recombinant Mouse Ahsa1, His-tagged E.coli His
Mouse Ahsa1-1568M Recombinant Mouse Ahsa1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque AHSA1-277R Recombinant Rhesus monkey AHSA1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque AHSA1-105R-B Recombinant Rhesus Macaque AHSA1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque AHSA1-105R Recombinant Rhesus Macaque AHSA1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish AHSA1-4140Z Recombinant Zebrafish AHSA1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

AHSA1 involved in several pathways and played different roles in them. We selected most pathways AHSA1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AHSA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

AHSA1 has several biochemical functions, for example, ATPase activator activity, chaperone binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AHSA1 itself. We selected most functions AHSA1 had, and list some proteins which have the same functions with AHSA1. You can find most of the proteins on our site.

Function Related Protein
ATPase activator activityATP1B1;ATP1B2;DNAJB1;AHSA2;DNAJC10;DNAJC15;MYBPC3;DNAJC19;TOR1AIP2
chaperone bindingDNAJB1;DNAJB6;PRNP;TIMM9;UBL4A;ERP29;USP13;TIMM10;AMFR
protein bindingMPPED2;USP44;TAF8;PLCE1;ISCA2;ALDOB;EREG;TUBB2A;JAM3

AHSA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AHSA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AHSA1.

HSP90AB1; HSP90AA1; GCH1; PTP4A3; EEF1D; HLA-B; EIF6; IRF3; C20orf24; NEK6; SCHIP1; FTSJ1; GSTK1

  • Q&As
  • Reviews

Q&As (10)

Ask a question
How does AHSA1 regulate the chaperone activity of HSP90? 09/22/2022

AHSA1 stimulates the ATPase activity of HSP90, enhancing its chaperone function and facilitating the folding, stabilization, and maturation of client proteins.

How does AHSA1's activity contribute to the conformational changes of HSP90 during the chaperone cycle? 08/08/2022

AHSA1 promotes conformational changes in HSP90 that enhance its ATPase activity, facilitating the release of client proteins at different stages of folding.

What is the role of AHSA1 in protein trafficking and localization within cells? 07/02/2022

AHSA1 assists in proper folding of proteins destined for specific cellular compartments, contributing to their accurate localization.

How can structural biology techniques, such as cryo-electron microscopy, contribute to understanding AHSA1's mechanism of action? 12/03/2021

These techniques can reveal the complex architecture of the AHSA1-HSP90 complex and provide insights into the conformational changes it undergoes during its chaperone cycle.

In the lab, what methods are used to study the dynamic changes in AHSA1 expression and its interaction with HSP90 under stress? 06/19/2021

Western blotting, immunofluorescence microscopy, and proximity ligation assays can be employed to study AHSA1 expression and its colocalization with HSP90 in stressed cells.

How is the interaction between AHSA1 and HSP90 characterized at the molecular level? 08/31/2020

Techniques like co-immunoprecipitation, surface plasmon resonance, and X-ray crystallography provide insights into the AHSA1-HSP90 interaction.

What biochemical assays are used to measure the ATPase-stimulating activity of AHSA1 on HSP90? 02/23/2020

Assays like malachite green or colorimetric methods can be used to quantify the release of inorganic phosphate, indicative of ATP hydrolysis, in the presence of AHSA1 and HSP90.

How can the AHSA1-HSP90 complex be targeted for therapeutic interventions? 06/04/2019

Small molecules that disrupt the AHSA1-HSP90 interaction could be designed to interfere with client protein folding and impact disease-associated pathways.

What are some examples of client proteins that depend on the AHSA1-HSP90 complex for proper folding and function? 03/15/2019

Client proteins include various kinases, steroid hormone receptors, and transcription factors involved in cell signaling and gene regulation.

How does AHSA1 influence the assembly of multi-protein complexes involved in cellular signaling pathways? 10/12/2018

AHSA1 can stabilize and facilitate the correct assembly of multi-protein complexes, thereby modulating cellular signaling cascades.

Customer Reviews (5)

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Reviews
01/17/2022

    Top-quality item well worth the price. Supportive customer service.

    12/23/2021

      Affordable yet exceptional quality. Customer service made the process easy.

      04/05/2020

        Quality met the price point, and the customer service was exceptional.

        06/09/2019

          Received superb customer service and a premium product at a fair price.

          09/28/2018

            Product quality justified the cost, and the customer service was excellent.

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