Akr1c6
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Official Full Name
aldo-keto reductase family 1, member C6
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| AKR1C6-1502M | Recombinant Mouse AKR1C6 Protein | Mammalian Cells | Mouse | His |
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| AKR1C6-439M | Recombinant Mouse AKR1C6 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| AKR1C6-439M-B | Recombinant Mouse AKR1C6 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
Akr1c6 involved in several pathways and played different roles in them. We selected most pathways Akr1c6 participated on our site, such as Arachidonic acid metabolism,Bile acid and bile salt metabolism,Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with Akr1c6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RA biosynthesis pathway | RDH14,CYP26A1,AKR1C21,RDH10,RDH13,RDH7,DHRS3,ADH8B,ALDH8A1,DHRS9 |
| Metabolism of lipids and lipoproteins | ALOX5B.3,MED7,FAM213B,ARSD,CTGF,DHCR7,CYP27B1,AGPAT6,CRAT,NFYBA |
| Signal Transduction | OXGR1A.3,SOX9A,USP9X,OXGR1,ARHGAP29B,TAS2R3,RGS18,RGS4,ARHGEF17,FGFBP1 |
| Signaling by Retinoic Acid | RDH14A,PDK2B,DHRS3,CRABP2B,CRABP1,PDK3,SDR16C5,FABP11A,RDH14B,DHRS3A |
| Retinoid metabolism and transport | BCO2,APOA4A,LRP10,CLPS,AKR1C21,APOM,APOC2,APOA4B.1,RBP1,AKR1C4 |
| Metabolism | CDO1,ATP5H,APOA5,SLC25A21,CYP2B6,PDK2B,PIK3R6,COX11,PPM1K,CEPT1A |
| Bile acid and bile salt metabolism | NCOA2,SLC27A5,AKR1C21,BRSK2,CYP7A1,CYP46A1,SLC27A2,AKR1C2,SLCO1B1,ACOT8 |
| Arachidonic acid metabolism | GPX3,CBR2,CYP1A2,CYP2AD6,CYP2C45,CYP2J5,CYP2P8,PLA2G4C,CYP2C54,CYP2C39 |
Protein Function
Akr1c6 has several biochemical functions, for example, (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity,(R)-2-hydroxyglutarate dehydrogenase activity,(R)-2-hydroxyisocaproate dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Akr1c6 itself. We selected most functions Akr1c6 had, and list some proteins which have the same functions with Akr1c6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| oxidoreductase activity | CYP4T8,ACOXL,CYP4F18,TRR1,CYP17A2,GPD1B,CHML,DHRS12,CYP4A14,HSD17B12B |
| steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | HSD3B5,AKR1C21,SDR16C6,HSD11B1LA,H2-KE6,HSD3B6,SDR42E1 |
| steroid dehydrogenase activity | HSD3B6,HSD3B5,HSD11B1LA,HSD17B11,SDR16C6,H2-KE6,AKR1C21,SDR42E1 |
| (R)-2-hydroxyisocaproate dehydrogenase activity | HSD11B1LA,HSD3B5,AKR1C21,SDR16C6,HSD3B6,SDR42E1,H2-KE6 |
| L-arabinose 1-dehydrogenase (NADP+) activity | AKR1C21,SDR16C6,H2-KE6,HSD11B1LA,HSD3B5,SDR42E1,HSD3B6 |
| 2-hydroxytetrahydrofuran dehydrogenase activity | H2-KE6,HSD3B5,SDR42E1,HSD3B6,AKR1C21,SDR16C6,HSD11B1LA |
| (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity | SDR42E1,HSD3B6,HSD11B1LA,HSD3B5,AKR1C21,H2-KE6,SDR16C6 |
| mevaldate reductase activity | HSD11B1LA,HSD3B5,SDR42E1,SDR16C6,HSD3B6,H2-KE6,AKR1C21 |
| 3-hydroxymenthone dehydrogenase activity | SDR42E1,HSD3B6,SDR16C6,H2-KE6,HSD3B5,AKR1C21,HSD11B1LA |
Interacting Protein
Akr1c6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Akr1c6 here. Most of them are supplied by our site. Hope this information will be useful for your research of Akr1c6.
Ywhae;Pgls;Hsd3b7
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