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Official Full Name aldo-keto reductase family 1, member C6
    • Species :
    • Mouse
    • Source :
    • Mammalian Cell
    • Tag :
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse AKR1C6-1502M Recombinant Mouse AKR1C6 Protein Mammalian Cell His

    akr1c6 involved in several pathways and played different roles in them. We selected most pathways akr1c6 participated on our site, such as Arachidonic acid metabolism, Bile acid and bile salt metabolism, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with akr1c6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Arachidonic acid metabolism CYP4A14; LTA4H; CYP4A10; CBR1L; PLA2G4F; PTGS2; CYP4A11; PLA2G2D; FAM213B; CBR1
    Bile acid and bile salt metabolism BRSK2; SCP2B; CYP8B2; SLC27A2; SLC27A2A; CYP27A1; AKR1C4; Alb; ACOT8; SLCO1B1
    Metabolism CHAT; CYP2K18; ESRRA; SPRB; KCNS3A; AMD2; GPHNA; SLC25A15B; B3GNT1; SCP2B
    Metabolism of lipids and lipoproteins PEMT; VAPB; COQ6; SACM1L; SPTLC1; GRHL1; MED16; NEU3; DHCR7; ACOT12
    RA biosynthesis pathway RDH14B; DHRS3A; DHRS9; RDH13; ALDH8A1; DHRS3; RDH10; CRABP1B; CRABP1A; ADH8A
    Retinoid metabolism and transport RBP1; AKR1C6; BCO2A; APOC2; APOA4B.2; CLPS; APOM; LRP12; APOA4A; AKR1C4
    Signal Transduction CDC42EP2; DRAP1; RAMP3; RHOT1A; TLE2; PRICKLE1; PNOCB; ARHGAP24; PRLRB; ABR
    Signaling by Retinoic Acid PDK2; ALDH8A1; PDK2B; AKR1C6; DHRS9; FABP11A; CRABP1; CRABP1B; DHRS4; SDR16C5

    akr1c6 has several biochemical functions, for example, (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity, (R)-2-hydroxyglutarate dehydrogenase activity, (R)-2-hydroxyisocaproate dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by akr1c6 itself. We selected most functions akr1c6 had, and list some proteins which have the same functions with akr1c6. You can find most of the proteins on our site.

    Function Related Protein
    (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity AKR1C21; HSD3B5; H2-KE6; AKR1C6; SDR16C6; SDR42E1; HSD3B6; HSD11B1LA
    (R)-2-hydroxyglutarate dehydrogenase activity H2-KE6; HSD3B5; AKR1C21; HSD11B1LA; SDR42E1; D2HGDH; SDR16C6; HSD3B6; AKR1C6
    (R)-2-hydroxyisocaproate dehydrogenase activity H2-KE6; AKR1C6; AKR1C21; SDR16C6; HSD3B5; SDR42E1; HSD11B1LA; HSD3B6
    17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity AKR1C6; HSD17B2
    2-hydroxytetrahydrofuran dehydrogenase activity SDR42E1; AKR1C6; HSD11B1LA; H2-KE6; SDR16C6; AKR1C21; HSD3B5; HSD3B6
    3-hydroxymenthone dehydrogenase activity SDR42E1; HSD3B5; H2-KE6; AKR1C6; AKR1C21; SDR16C6; HSD3B6; HSD11B1LA
    3-ketoglucose-reductase activity SDR16C6; SDR42E1; AKR1C6; HSD11B1LA; AKR1C21; H2-KE6; HSD3B6; HSD3B5
    5-exo-hydroxycamphor dehydrogenase activity SDR42E1; HSD3B5; HSD11B1LA; AKR1C6; SDR16C6; H2-KE6; AKR1C21; HSD3B6
    C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity HSD3B6; HSD3B5; H2-KE6; AKR1C21; SDR16C6; AKR1C6; SDR42E1; HSD11B1LA
    D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity SDR42E1; HSD11B1LA; HSD3B5; H2-KE6; HSD3B6; SDR16C6; AKR1C21; AKR1C6
    D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity AKR1C6; HSD3B5; HSD11B1LA; SDR16C6; H2-KE6; AKR1C21; SDR42E1; HSD3B6
    D-xylose:NADP reductase activity SDR42E1; HSD3B6; HSD3B5; SDR16C6; HSD11B1LA; AKR1C6; H2-KE6; AKR1C21
    L-arabinose 1-dehydrogenase (NADP+) activity H2-KE6; HSD11B1LA; SDR42E1; AKR1C21; AKR1C6; HSD3B5; SDR16C6; HSD3B6
    L-arabinose:NADP reductase activity SDR42E1; HSD3B6; AKR1C21; HSD11B1LA; H2-KE6; AKR1C6; HSD3B5; SDR16C6
    L-xylulose reductase (NAD+) activity AKR1C6; SDR42E1; H2-KE6; HSD11B1LA; AKR1C21; HSD3B5; SDR16C6; HSD3B6
    acetoin dehydrogenase activity SDR42E1; AKR1C6; HSD3B6; SDR16C6; AKR1C21; H2-KE6; HSD11B1LA; HSD3B5
    aldo-keto reductase (NADP) activity KCNAB2; HSD11B1LA; MIOX; H2-KE6; SPR; AKR1B10; SDR16C6; CYB5A; HSD3B5; SDR42E1
    androsterone dehydrogenase activity AKR1C6; AKR1C4; AKR1C3; AKR1C21
    dihydrotestosterone 17-beta-dehydrogenase activity HSD3B5; AKR1C21; HSD3B6; SDR16C6; AKR1C6; AKR1C3; SDR42E1; HSD11B1LA; H2-KE6
    epoxide dehydrogenase activity SDR16C6; AKR1C21; HSD3B5; SDR42E1; H2-KE6; HSD11B1LA; HSD3B6; AKR1C6
    estradiol 17-beta-dehydrogenase activity HSD17B12A; HSD17B10; HSD17B14; HSD17B12B; HSD17B7; HSD17B6; H2-KE6; RDH8; RDH8A; HSD17B12
    gluconate dehydrogenase activity SDR16C6; AKR1C21; HSD11B1LA; HSD3B6; SDR42E1; H2-KE6; AKR1C6; HSD3B5
    isocitrate dehydrogenase activity AKR1C21; AKR1C6; HSD3B6; HSD11B1LA; HSD3B5; SDR16C6; H2-KE6; SDR42E1
    mevaldate reductase activity HSD3B6; H2-KE6; AKR1C6; SDR42E1; HSD3B5; HSD11B1LA; AKR1C21; SDR16C6
    oxidoreductase activity JMJD1C; CMAH; CYP1A2; FAM84B; TXNDC17; SCD5; PRODH2; AKR1A1A; GPD1A; CYBASC3
    oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor AKR1C4; AKR1C6; CBR1; AKR1C21; AKR1C2; DHRS4; AKR1C3; DCXR; NDUFS7
    phenylcoumaran benzylic ether reductase activity AKR1C6; SDR16C6; SDR42E1; HSD3B6; HSD11B1LA; HSD3B5; H2-KE6; AKR1C21
    retinal dehydrogenase activity AKR1B8; ALDH8A1; Aldh1a7; ALDH1A1; AKR1C6; AKR1B10; AKR1C4; AKR1C3; ALDH1A3
    steroid dehydrogenase activity H2-KE6; AKR1C21; HSD3B6; SDR16C6; HSD17B11; AKR1C6; HSD11B1LA; HSD3B5; SDR42E1
    steroid dehydrogenase activity, acting on the CH-CH group of donors SDR42E1; HSD3B5; H2-KE6; AKR1C21; SDR16C6; HSD11B1LA; AKR1C6; HSD3B6
    steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor SDR42E1; HSD3B5; SDR16C6; H2-KE6; HSD11B1LA; AKR1C21; HSD3B6; AKR1C6
    testosterone 17-beta-dehydrogenase (NADP+) activity HSD17B3; HSD17B14; AKR1C6; AKR1C3
    very long-chain-3-hydroxyacyl-CoA dehydrogenase activity SDR16C6; AKR1C6; SDR42E1; H2-KE6; HSD11B1LA; AKR1C21; HSD3B5; HSD3B6

    akr1c6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with akr1c6 here. Most of them are supplied by our site. Hope this information will be useful for your research of akr1c6.

    Ywhae; Pgls; Hsd3b7

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