Official Full Name | aldo-keto reductase family 1, member C6 |
Synonyms | ; |
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Akr1c6 involved in several pathways and played different roles in them. We selected most pathways Akr1c6 participated on our site, such as Arachidonic acid metabolism, Bile acid and bile salt metabolism, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with Akr1c6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Arachidonic acid metabolism | CYP2J5; ALOX5B.3; CYP4F2; GGT5A; CYP2P8; LTA4H; ALOX8; GPX8; CYP1A2; FAAH2 |
Bile acid and bile salt metabolism | CYP46A1; SLC27A2; NCOA2; Alb; AKR1C6; BRSK2; CYP7A1; CYP8B2; SLCO1B1; AKR1C2 |
Metabolism | SLC25A15A; SACM1LA; BCKDK; SLC25A21; SLC35D2; TPMT.2; PLB1; NDUFAF2; ACOT11; DIO2 |
Metabolism of lipids and lipoproteins | SIN3B; CLPS; APOF; SLC25A1A; ESRRA; CPTP; MTF1; YY2; CYP11B1; SREBF2 |
RA biosynthesis pathway | RDH10; AKR1C6; AKR1C21; DHRS4; CRABP1; ADH8B; DHRS9; RDH14B; ALDH8A1; SDR16C5 |
Retinoid metabolism and transport | BCO2; BCO2L; LRP10; AKR1C4; APOA4A; LRP12; RBP2A; AKR1C21; RBP1; CLPS |
Signal Transduction | PTHLH; RTKN; WWOX; CDC42EP3; USP34; ARHGEF3; DHRS9; PTPRUB; ADM2; PTPRK |
Signaling by Retinoic Acid | PDK2B; ALDH8A1; RDH14A; RDH14B; DHRS4; FABP11B; CRABP1; PDK2; PDK4; FABP11A |
Akr1c6 has several biochemical functions, for example, (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity, (R)-2-hydroxyglutarate dehydrogenase activity, (R)-2-hydroxyisocaproate dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Akr1c6 itself. We selected most functions Akr1c6 had, and list some proteins which have the same functions with Akr1c6. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity | AKR1C6; HSD3B5; SDR42E1; H2-KE6; SDR16C6; AKR1C21; HSD3B6; HSD11B1LA |
(R)-2-hydroxyglutarate dehydrogenase activity | AKR1C21; HSD11B1LA; SDR16C6; D2HGDH; SDR42E1; HSD3B6; AKR1C6; H2-KE6; HSD3B5 |
(R)-2-hydroxyisocaproate dehydrogenase activity | H2-KE6; AKR1C6; SDR16C6; SDR42E1; HSD3B6; HSD3B5; HSD11B1LA; AKR1C21 |
17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity | HSD17B2; AKR1C6 |
2-hydroxytetrahydrofuran dehydrogenase activity | SDR16C6; H2-KE6; HSD3B6; AKR1C21; AKR1C6; HSD11B1LA; HSD3B5; SDR42E1 |
3-hydroxymenthone dehydrogenase activity | SDR16C6; AKR1C21; H2-KE6; HSD3B6; SDR42E1; AKR1C6; HSD11B1LA; HSD3B5 |
3-ketoglucose-reductase activity | AKR1C21; H2-KE6; AKR1C6; SDR42E1; HSD3B5; HSD3B6; SDR16C6; HSD11B1LA |
5-exo-hydroxycamphor dehydrogenase activity | AKR1C21; HSD3B5; HSD11B1LA; SDR16C6; SDR42E1; H2-KE6; AKR1C6; HSD3B6 |
C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity | HSD3B5; AKR1C21; SDR42E1; HSD11B1LA; SDR16C6; HSD3B6; AKR1C6; H2-KE6 |
D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity | HSD3B5; HSD3B6; H2-KE6; AKR1C21; AKR1C6; HSD11B1LA; SDR16C6; SDR42E1 |
D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity | AKR1C21; HSD11B1LA; SDR42E1; H2-KE6; SDR16C6; AKR1C6; HSD3B6; HSD3B5 |
D-xylose:NADP reductase activity | HSD11B1LA; AKR1C6; HSD3B6; H2-KE6; SDR42E1; AKR1C21; SDR16C6; HSD3B5 |
L-arabinose 1-dehydrogenase (NADP+) activity | AKR1C21; SDR42E1; HSD3B5; HSD11B1LA; AKR1C6; HSD3B6; H2-KE6; SDR16C6 |
L-arabinose:NADP reductase activity | SDR16C6; HSD3B5; H2-KE6; AKR1C6; AKR1C21; HSD11B1LA; SDR42E1; HSD3B6 |
L-xylulose reductase (NAD+) activity | AKR1C6; SDR16C6; HSD3B5; SDR42E1; AKR1C21; H2-KE6; HSD11B1LA; HSD3B6 |
acetoin dehydrogenase activity | HSD3B6; HSD3B5; AKR1C21; HSD11B1LA; AKR1C6; SDR42E1; SDR16C6; H2-KE6 |
aldo-keto reductase (NADP) activity | H2-KE6; SDR16C6; AKR1C3; HSD3B5; AKR1B10; CYB5A; SDR42E1; KCNAB2; AKR1B1; AKR7A3 |
androsterone dehydrogenase activity | AKR1C21; AKR1C4; AKR1C6; AKR1C3 |
dihydrotestosterone 17-beta-dehydrogenase activity | SDR42E1; SDR16C6; HSD3B5; HSD3B6; AKR1C21; AKR1C6; HSD11B1LA; AKR1C3; H2-KE6 |
epoxide dehydrogenase activity | H2-KE6; AKR1C6; HSD3B6; HSD11B1LA; AKR1C21; SDR42E1; HSD3B5; SDR16C6 |
estradiol 17-beta-dehydrogenase activity | AKR1C6; RDH8B; RDH8A; HSD17B12A; HSD17B1; HSD17B7; HSD17B10; HSD17B12B; AKR1B15; HSD17B11 |
gluconate dehydrogenase activity | HSD3B6; SDR42E1; AKR1C6; AKR1C21; HSD11B1LA; H2-KE6; HSD3B5; SDR16C6 |
isocitrate dehydrogenase activity | H2-KE6; AKR1C21; SDR16C6; HSD3B5; HSD11B1LA; SDR42E1; HSD3B6; AKR1C6 |
mevaldate reductase activity | HSD3B5; HSD3B6; HSD11B1LA; SDR42E1; AKR1C6; H2-KE6; SDR16C6; AKR1C21 |
oxidoreductase activity | UOX; FADS3; SRD5A3; SC4MOL; DHRS11B; CYP24A1; HSD3B5; DHRS7; KDM5BB; HSD17B13 |
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | DCXR; AKR1C6; AKR1C21; DHRS4; CBR1; NDUFS7; AKR1C3; AKR1C2; AKR1C4 |
phenylcoumaran benzylic ether reductase activity | H2-KE6; HSD3B6; AKR1C6; AKR1C21; HSD11B1LA; SDR42E1; SDR16C6; HSD3B5 |
retinal dehydrogenase activity | AKR1C6; AKR1B8; AKR1C3; AKR1B10; ALDH1A1; Aldh1a7; AKR1C4; ALDH1A3; ALDH8A1 |
steroid dehydrogenase activity | H2-KE6; HSD11B1LA; AKR1C6; HSD3B6; SDR42E1; AKR1C21; HSD3B5; HSD17B11; SDR16C6 |
steroid dehydrogenase activity, acting on the CH-CH group of donors | H2-KE6; AKR1C6; HSD11B1LA; SDR16C6; HSD3B6; HSD3B5; SDR42E1; AKR1C21 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | HSD3B5; AKR1C6; SDR16C6; SDR42E1; AKR1C21; HSD3B6; H2-KE6; HSD11B1LA |
testosterone 17-beta-dehydrogenase (NADP+) activity | AKR1C3; HSD17B14; HSD17B3; AKR1C6 |
very long-chain-3-hydroxyacyl-CoA dehydrogenase activity | H2-KE6; HSD3B5; AKR1C6; SDR16C6; HSD3B6; SDR42E1; AKR1C21; HSD11B1LA |
Akr1c6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Akr1c6 here. Most of them are supplied by our site. Hope this information will be useful for your research of Akr1c6.
Ywhae; Pgls; Hsd3b7
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