Akr1c6

  • Official Full Name

    aldo-keto reductase family 1, member C6
Cat.# Product name Source (Host) Species Tag Protein Length Price
AKR1C6-1502M Recombinant Mouse AKR1C6 Protein Mammalian Cells Mouse His
AKR1C6-439M Recombinant Mouse AKR1C6 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
AKR1C6-439M-B Recombinant Mouse AKR1C6 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    Akr1c6 involved in several pathways and played different roles in them. We selected most pathways Akr1c6 participated on our site, such as Arachidonic acid metabolism,Bile acid and bile salt metabolism,Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with Akr1c6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism of lipids and lipoproteins MED23,FA2H,SLC27A5,ESRRA,AWAT1,CYP4F22,CYP4F11,SGMS2,PHOSPHO1,HSD17B11
    Arachidonic acid metabolism CYP1A2,CYP2J5,PTGDSA,PLA2G6,PTGESL,ALOX15,DPEP1,PLA2G5,PTGIS,CYP4F22
    Signal Transduction WIPF2,CHN1,OR10A5,PYGO2,RSPO3,EVC,RLBP1A,IGF2BP1,TLE3,PMEPA1
    Bile acid and bile salt metabolism Alb,AKR1C4,CYP7A1,SLC27A2,SLC27A5,BRSK2,AKR1C2,AKR1C21,SLCO1B1,NCOA2
    RA biosynthesis pathway ADH8A,RDH14A,RDH14,RDH13,CRABP1,CYP26A1,RDH14B,ADH8B,RDH7,DHRS3A
    Retinoid metabolism and transport BCO2L,AKR1C4,APOA4A,BCO2A,LRP12,RBP2A,CLPS,APOM,LRP10,APOC2
    Signaling by Retinoic Acid RDH10,DHRS4,RDH14B,PDK3,RDH7,FABP11B,CRABP2B,CRABP1A,PDK2B,CRABP1B
    Metabolism FMODA,COL4A3BP,PEMT,CYP3C1,CHP,CIAPIN1,UROC1,LYVE1,ATP5S,AADAC

    Protein Function

    Akr1c6 has several biochemical functions, for example, (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity,(R)-2-hydroxyglutarate dehydrogenase activity,(R)-2-hydroxyisocaproate dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Akr1c6 itself. We selected most functions Akr1c6 had, and list some proteins which have the same functions with Akr1c6. You can find most of the proteins on our site.

    Function Related Protein
    testosterone 17-beta-dehydrogenase (NADP+) activity HSD17B14,HSD17B3,AKR1C3
    L-xylulose reductase (NAD+) activity HSD11B1LA,SDR16C6,SDR42E1,HSD3B5,AKR1C21,H2-KE6,HSD3B6
    isocitrate dehydrogenase activity H2-KE6,SDR42E1,SDR16C6,AKR1C21,HSD3B5,HSD11B1LA,HSD3B6
    epoxide dehydrogenase activity H2-KE6,HSD3B6,AKR1C21,SDR16C6,HSD11B1LA,HSD3B5,SDR42E1
    (R)-2-hydroxyisocaproate dehydrogenase activity HSD3B5,AKR1C21,SDR42E1,H2-KE6,HSD3B6,SDR16C6,HSD11B1LA
    2-hydroxytetrahydrofuran dehydrogenase activity AKR1C21,HSD3B6,H2-KE6,SDR42E1,HSD11B1LA,SDR16C6,HSD3B5
    oxidoreductase activity DAO.2,CYP46A1.3,WWOX,CREG1,HTATIP2,CYP11C1,ADH1,RDH13,RDH8A,CYP2C8
    17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity HSD17B2
    D-xylose:NADP reductase activity H2-KE6,SDR42E1,AKR1C21,SDR16C6,HSD3B5,HSD3B6,HSD11B1LA

    Interacting Protein

    Akr1c6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Akr1c6 here. Most of them are supplied by our site. Hope this information will be useful for your research of Akr1c6.

    Ywhae;Pgls;Hsd3b7

    Resources

    References

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