Akr1c6

  • Official Full Name

    aldo-keto reductase family 1, member C6
Cat.# Product name Source (Host) Species Tag Protein Length Price
AKR1C6-1502M Recombinant Mouse AKR1C6 Protein Mammalian Cells Mouse His
AKR1C6-439M Recombinant Mouse AKR1C6 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
AKR1C6-439M-B Recombinant Mouse AKR1C6 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    Akr1c6 involved in several pathways and played different roles in them. We selected most pathways Akr1c6 participated on our site, such as Arachidonic acid metabolism,Bile acid and bile salt metabolism,Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with Akr1c6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Retinoid metabolism and transport LRP12,APOM,AKR1C4,RBP1,BCO2A,LRP10,APOA4B.2,APOA4B.1,CLPS,RBP2A
    Signal Transduction GRB10A,ACKR4,GREM2,PTH2,KTN1,ABI1B,CCNT2A,ABHD6B,KIF7,PLEKHG2
    RA biosynthesis pathway RDH14A,AKR1C21,SDR16C5,RDH10,CRABP1,ADH8A,RDH7,RDH14B,ADH8B,DHRS4
    Arachidonic acid metabolism PLA2G2D,CYP4T8,GPX1,ALOX5A,GPX2,ALOX5B.2,ALOX12B,GPX7,CYP1A1,PTGES2
    Metabolism HPSE,BSG,SACM1LB,AQP1A.2,NDUFAF7,MAPK1IP1L,SURF1,LYVE1,CYP46A1,SYT5
    Metabolism of lipids and lipoproteins ALOX5AP,GLTP,CYP2Y3,GGTLC1,ABHD4,AGPAT6,SLC25A1,CPNE1,YY2,CYP2R1
    Bile acid and bile salt metabolism Alb,CYP27A1,CYP46A1,SLC27A2,SLCO1B1,NCOA2,ACOT8,SLC27A5,CYP8B2,AKR1C21
    Signaling by Retinoic Acid PDK3B,RDH14,CRABP1A,DHRS3A,RARGA,PDK2B,FABP11A,ALDH8A1,FABP11B,RDH14A

    Protein Function

    Akr1c6 has several biochemical functions, for example, (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity,(R)-2-hydroxyglutarate dehydrogenase activity,(R)-2-hydroxyisocaproate dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Akr1c6 itself. We selected most functions Akr1c6 had, and list some proteins which have the same functions with Akr1c6. You can find most of the proteins on our site.

    Function Related Protein
    L-arabinose:NADP reductase activity HSD3B6,SDR42E1,AKR1C21,HSD11B1LA,SDR16C6,H2-KE6,HSD3B5
    L-xylulose reductase (NAD+) activity HSD3B6,AKR1C21,HSD11B1LA,SDR16C6,SDR42E1,HSD3B5,H2-KE6
    3-hydroxymenthone dehydrogenase activity HSD3B5,AKR1C21,HSD11B1LA,HSD3B6,H2-KE6,SDR16C6,SDR42E1
    steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor H2-KE6,HSD11B1LA,AKR1C21,SDR16C6,HSD3B5,SDR42E1,HSD3B6
    D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity SDR16C6,HSD3B6,SDR42E1,HSD11B1LA,AKR1C21,H2-KE6,HSD3B5
    oxidoreductase activity CYP2C39,RDH10B,RDH8A,KDM1B,DMGDH,AOX3,SCCPDH,HEPHL1,CYP2J5,F8
    dihydrotestosterone 17-beta-dehydrogenase activity HSD3B6,H2-KE6,SDR16C6,HSD11B1LA,AKR1C21,HSD3B5,AKR1C3,SDR42E1
    2-hydroxytetrahydrofuran dehydrogenase activity AKR1C21,H2-KE6,HSD3B6,SDR16C6,SDR42E1,HSD3B5,HSD11B1LA
    estradiol 17-beta-dehydrogenase activity RDH8,HSD17B6,HSD17B7,H2-KE6,HSD17B12B,HSD17B12A,HSD17B12,HSD17B14,RDH8B,AKR1B15

    Interacting Protein

    Akr1c6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Akr1c6 here. Most of them are supplied by our site. Hope this information will be useful for your research of Akr1c6.

    Ywhae;Pgls;Hsd3b7

    Resources

    References

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