Akr1c6

  • Official Full Name

    aldo-keto reductase family 1, member C6
Cat.# Product name Source (Host) Species Tag Protein Length Price
AKR1C6-1502M Recombinant Mouse AKR1C6 Protein Mammalian Cells Mouse His
AKR1C6-439M Recombinant Mouse AKR1C6 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
AKR1C6-439M-B Recombinant Mouse AKR1C6 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    Akr1c6 involved in several pathways and played different roles in them. We selected most pathways Akr1c6 participated on our site, such as Arachidonic acid metabolism,Bile acid and bile salt metabolism,Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with Akr1c6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Arachidonic acid metabolism ALOX8,CYP4A11,GPX6,PTGR1,GGT1A,GGT1,DPEP1,CYP2AD6,GPX3,CYP2C9
    Bile acid and bile salt metabolism AKR1C2,AKR1C4,SLC27A2,SLC27A2A,SCP2B,SLC27A5,BRSK2,Alb,CYP8B2,NCOA2
    Retinoid metabolism and transport APOA4B.2,BCO2L,AKR1C21,LRP12,RBP4,AKR1C4,APOM,BCO2A,APOC2,LRP10
    Signaling by Retinoic Acid CRABP1A,CRABP1,RARGA,PDK3B,FABP11A,DHRS4,DHRS3A,RDH13,CRABP2B,PDK2B
    RA biosynthesis pathway RDH14B,RDH14A,RDH10,CRABP1A,ADH8A,CRABP1,RDH14,CYP26A1,CRABP1B,DHRS3
    Metabolism of lipids and lipoproteins OSBP,MED16,ARF3,PPM1LB,DPEP2,SLC25A1,TIAM2,LPA,HSD17B11,MED20
    Metabolism GLRX,NDOR1,AFMID,ACY3.2,LMF2,PDPR,CHP,NUBP2,UGT1B2,MED22
    Signal Transduction CSNK1G2,DSCAMA,GPR31B,ADM2A,CHN1,PTGDR2,PNOC,CDH5,AMOTL2,PTHLHA

    Protein Function

    Akr1c6 has several biochemical functions, for example, (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity,(R)-2-hydroxyglutarate dehydrogenase activity,(R)-2-hydroxyisocaproate dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Akr1c6 itself. We selected most functions Akr1c6 had, and list some proteins which have the same functions with Akr1c6. You can find most of the proteins on our site.

    Function Related Protein
    epoxide dehydrogenase activity AKR1C21,HSD11B1LA,SDR16C6,H2-KE6,SDR42E1,HSD3B5,HSD3B6
    L-xylulose reductase (NAD+) activity HSD11B1LA,AKR1C21,SDR16C6,H2-KE6,HSD3B6,SDR42E1,HSD3B5
    testosterone 17-beta-dehydrogenase (NADP+) activity HSD17B14,HSD17B3,AKR1C3
    dihydrotestosterone 17-beta-dehydrogenase activity AKR1C3,AKR1C21,HSD3B6,SDR16C6,HSD11B1LA,HSD3B5,H2-KE6,SDR42E1
    2-hydroxytetrahydrofuran dehydrogenase activity HSD3B6,HSD3B5,HSD11B1LA,SDR42E1,AKR1C21,H2-KE6,SDR16C6
    very long-chain-3-hydroxyacyl-CoA dehydrogenase activity SDR16C6,HSD3B5,HSD3B6,H2-KE6,HSD11B1LA,AKR1C21,SDR42E1
    steroid dehydrogenase activity, acting on the CH-CH group of donors SDR16C6,AKR1C21,SDR42E1,HSD3B5,HSD11B1LA,H2-KE6,HSD3B6
    17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity HSD17B2
    (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity HSD3B5,SDR16C6,HSD11B1LA,HSD3B6,H2-KE6,AKR1C21,SDR42E1

    Interacting Protein

    Akr1c6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Akr1c6 here. Most of them are supplied by our site. Hope this information will be useful for your research of Akr1c6.

    Ywhae;Pgls;Hsd3b7

    Resources

    References

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