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Official Full Name aldehyde dehydrogenase 3 family, member B2
Background This gene encodes a member of the aldehyde dehydrogenase family, a group of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The gene of this particular family member is over 10 kb in length. The expression of these transcripts is restricted to the salivary gland among the human tissues examined. Alternate transcriptional splice variants have been characterized.
Synonyms ALDH3B2; aldehyde dehydrogenase 3 family, member B2; ALDH8; aldehyde dehydrogenase family 3 member B2; acetaldehyde dehydrogenase 8; aldehyde dehydrogenase 8; OTTHUMP00000235616
    • Species :
    • Human
    • Source :
    • E.coli
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ALDH3B2-448H Recombinant Human ALDH3B2 Protein, GST-tagged Wheat Germ GST
    Human ALDH3B2-497H Recombinant Human Aldehyde Dehydrogenase 3 Family, Member B2, GST-tagged E.coli GST
    Human ALDH3B2-498H Recombinant Human Aldehyde Dehydrogenase 3 Family, Member B2, His-tagged E.coli His
    Human ALDH3B2-59HCL Recombinant Human ALDH3B2 cell lysate N/A

    aldh3b2 involved in several pathways and played different roles in them. We selected most pathways aldh3b2 participated on our site, such as Glycolysis / Gluconeogenesis, Histidine metabolism, Tyrosine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with aldh3b2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycolysis / Gluconeogenesis PGAM1B; ALDH3B1; ACSS2; ALDOCA; PKM2; TPI1B; ALDH7A1; DLAT; FBP1B; ACSS1
    Histidine metabolism HNMT; UROC1; ALDH1A3; CNDP1; FTCD; ALDH7A1; ALDH2.2; HAL; ALDH9A1A.1; MAOA
    Tyrosine metabolism ALDH3B1; FAHD1; DCT; ADH2-1; MAOA; TH; AOX3; ADH1; AOC3; FAH
    Phenylalanine metabolism IL4I1; GM4952; MAOB; HPDB; PAH; GOT2A; MIF; HPDA; GOT1; ALDH3A1
    beta-Alanine metabolism GAD1B; HADHA; ALDH9A1; SMOX; HADHAA; GAD2; ALDH7A1; ACADM; ALDH9A1B; CARNS1
    Metabolism of xenobiotics by cytochrome P ALDH1A3; CBR1L; HSD11B1; GSTT1B; ADH1; MGST1; UGT1AB; UGT1A6A; GSTM3; UGT2A2
    Drug metabolism - cytochrome P UGT2A1; AOX4; UGT5G1; MGST1; FMO2; UGT1A1; GSTM7; GSTT1B; GSTT2B; GSTO1
    Metabolic pathways ATP6V0A2B; DAO.3; FUT6; NADK2; MTHFR; ATIC; ATP5I; AHCY; MAT2AA; CECR1
    Chemical carcinogenesis CYP2C38; CYP2C55; GSTT1; ADH2-1; CYP2C9; AHA-1; CYP2C37; ADH1; FAM84B; PTGS2

    aldh3b2 has several biochemical functions, for example, 3-chloroallyl aldehyde dehydrogenase activity, aldehyde dehydrogenase (NAD) activity, aldehyde dehydrogenase [NAD(P)+] activity. Some of the functions are cooperated with other proteins, some of the functions could acted by aldh3b2 itself. We selected most functions aldh3b2 had, and list some proteins which have the same functions with aldh3b2. You can find most of the proteins on our site.

    Function Related Protein
    3-chloroallyl aldehyde dehydrogenase activity Aldh1a7; ALDH3A2; ALDH9A1; ALDH3A1; ALDH3B1; ALDH2.1; ALDH3B2; ALDH1A1; ALDH3A2A; ALDH3A2B
    aldehyde dehydrogenase (NAD) activity ALDH9A1B; ALDH7A1; ALDH9A1A.1; ALDH8A1; Aldh1a7; ALDH5A1; ALDH1L2; ALDH9A1; ALDH16A1; ALDH2
    aldehyde dehydrogenase [NAD(P)+] activity ALDH3A2B; ALDH3A1; ALDH2; ALDH1A3; ALDH3A2A; ALDH3B2; ALDH3A2; ALDH3B1

    aldh3b2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with aldh3b2 here. Most of them are supplied by our site. Hope this information will be useful for your research of aldh3b2.

    Hartomo, TB; Pham, TVH; et al. Involvement of aldehyde dehydrogenase 1A2 in the regulation of cancer stem cell properties in neuroblastoma. INTERNATIONAL JOURNAL OF ONCOLOGY 46:1089-1098(2015).
    Zhang, RL; Miao, Q; et al. Genome-wide DNA methylation analysis in alcohol dependence. ADDICTION BIOLOGY 18:392-403(2013).
    Holmes, RS; Hempel, J; et al. Comparative studies of vertebrate aldehyde dehydrogenase 3: Sequences, structures, phylogeny and evolution. Evidence for a mammalian origin for the ALDH3A1 gene. CHEMICO-BIOLOGICAL INTERACTIONS 191:113-121(2011).
    Holmes, RS; et al. Biochemical Genetics of Opossum Aldehyde Dehydrogenase 3: Evidence for Three ALDH3A-Like Genes and an ALDH3B-Like Gene. BIOCHEMICAL GENETICS 48:287-303(2010).

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