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ALDH9A1

  • Official Full Name

    aldehyde dehydrogenase 9 family, member A1

  • Overview

    This protein belongs to the aldehyde dehydrogenase family of proteins. It has a high activity for oxidation of gamma-aminobutyraldehyde and other amino aldehydes. The enzyme catalyzes the dehydrogenation of gamma-aminobutyraldehyde to gamma-aminobutyric acid (GABA). This isozyme is a tetramer of identical 54-kD subunits.
  • Synonyms

    ALDH9A1; aldehyde dehydrogenase 9 family, member A1; ALDH4, ALDH7, ALDH9; 4-trimethylaminobutyraldehyde dehydrogenase; E3; 4 trimethylaminobutyraldehyde dehydrogenase; AL9A1_HUMAN; aldehyde dehydrogenase (NAD+); Aldehyde dehydrogenase 9A1; Aldehyde dehydrogenase E3 isozyme; Aldehyde dehydrogenase family 9 member A1; ALDH4; ALDH7; ALDH9; Gamma aminobutyraldehyde dehydrogenase; Gamma-aminobutyraldehyde dehydrogenase; R aminobutyraldehyde dehydrogenase; R-aminobutyraldehyde dehydrogenase; TMABADH; OTTHUMP00000032604;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ALDH9A1-454H Recombinant Human ALDH9A1 Protein, GST-tagged Wheat Germ GST
Human ALDH9A1-61HCL Recombinant Human ALDH9A1 cell lysate N/A
Human ALDH9A1-6469H Recombinant Human ALDH9A1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human ALDH9A1-1418HF Recombinant Full Length Human ALDH9A1 Protein, GST-tagged In Vitro Cell Free System GST 494 amino acids
Human ALDH9A1-3945H Recombinant Human ALDH9A1 protein, His-tagged E.coli His 285-412 aa
Mouse Aldh9a1-1360M Recombinant Mouse Aldh9a1 protein, His & T7-tagged E.coli His/T7 Leu322~Phe494 (Accession # Q9JLJ2)
Mouse Aldh9a1-1595M Recombinant Mouse Aldh9a1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat ALDH9A1-624R Recombinant Rat ALDH9A1 Protein Mammalian Cell His
Rat ALDH9A1-280R Recombinant Rat ALDH9A1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ALDH9A1-280R-B Recombinant Rat ALDH9A1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ALDH9A1 Related Articles

ALDH9A1 involved in several pathways and played different roles in them. We selected most pathways ALDH9A1 participated on our site, such as Glycolysis / Gluconeogenesis, Ascorbate and aldarate metabolism, Fatty acid degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALDH9A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycolysis / GluconeogenesisFBP1B;AKR1A1B;PKMA;PFKP;MINPP1B;PGAM2;PFKMA;PCK2;MINPP1A
Ascorbate and aldarate metabolismUGT2A2;UGT5G1;MIOX;ALDH3A2A;UGT2B15;UGT1A7C;UGT1A2;ALDH9A1;UGT1A6
Fatty acid degradationACSL1;ACSBG1;ADH7;ACSL4B;CPT1C;ACSBG2;CYP4A14;HADHA;ALDH2.2
Valine, leucine and isoleucine degradationHMGCS2;ACAA1;ACAA1A;ACAA2;OXCT1;ALDH3A2;ACSF3;MCCC2;HADHAA
Lysine degradationALDH2.2;PLOD2;ALDH2;HADH;GCDHA;C2orf34;EHMT1;SUV39H1A;ALDH9A1
Arginine and proline metabolismSAT1A.2;SAT1A.1;P4HA1A;GOT1;HOGA1;ALDH3A2;P4HA2;P4HA3;GAMT
Histidine metabolismASPA;AMDHD1;ALDH1A3;ALDH2;ALDH7A1;ALDH2.2;HDC;CNDP2;ABP1
Tryptophan metabolismAOX4;AOX3L1;GCDH;CYP4F12;CYP1A;AOC1;TPH1B;KYNU;ALDH1B1
beta-Alanine metabolismALDH3B1;UPB1;SMOX;ALDH1A3;GAD2;GAD1;ALDH6A1;ALDH2.1;ALDH2
Glycerolipid metabolismDGAT1A;AGPAT9L;DGKG;STIL;AKR1B10;LCLAT1;ALDH2;DGKD;PNLIPRP3
Pyruvate metabolismLDHA;ALDH1B1;ACAT1;DLDH;ME2;PCK1;PDPR;ACSS1;ACYP2
Metabolic pathwaysCYP2S1;HYAL4;PIP5K1C;ETNK1;NDUFV3;TKTL2;HAO2;GFPT2;BCKDHA

ALDH9A1 has several biochemical functions, for example, 1-pyrroline dehydrogenase activity, 3-chloroallyl aldehyde dehydrogenase activity, 4-trimethylammoniobutyraldehyde dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ALDH9A1 itself. We selected most functions ALDH9A1 had, and list some proteins which have the same functions with ALDH9A1. You can find most of the proteins on our site.

Function Related Protein
1-pyrroline dehydrogenase activity
3-chloroallyl aldehyde dehydrogenase activityALDH2.1;ALDH3B2;ALDH3A1;ALDH1A1;ALDH9A1;ALDH3B1;ALDH3A2;Aldh1a7;ALDH3A2B
4-trimethylammoniobutyraldehyde dehydrogenase activityALDH9A1;ALDH9A1A.1;ALDH9A1B
aldehyde dehydrogenase (NAD) activityALDH1B1;ALDH8A1;ALDH3A2B;Aldh1a7;ALDH9A1B;ALDH4A1;ALDH16A1;ALDH1L2;ALDH9A1A.1
aminobutyraldehyde dehydrogenase activityALDH9A1A.1;ALDH9A1;ALDH9A1B

ALDH9A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALDH9A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALDH9A1.

HLA-B; USP46; TNIP3; DDA1; flgH1; GABARAPL1

Yang, Y; Zhou, W; et al. NEK2 mediates ALDH1A1-dependent drug resistance in multiple myeloma. ONCOTARGET 5:11986-11997(2014).
Li, XS; Xu, Q; et al. ALDH1A1 overexpression is associated with the progression and prognosis in gastric cancer. BMC CANCER 14:-(2014).
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