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Official Full Name aldehyde dehydrogenase 9 family, member A1
Background This protein belongs to the aldehyde dehydrogenase family of proteins. It has a high activity for oxidation of gamma-aminobutyraldehyde and other amino aldehydes. The enzyme catalyzes the dehydrogenation of gamma-aminobutyraldehyde to gamma-aminobutyric acid (GABA). This isozyme is a tetramer of identical 54-kD subunits.
Synonyms ALDH9A1; aldehyde dehydrogenase 9 family, member A1; ALDH4, ALDH7, ALDH9; 4-trimethylaminobutyraldehyde dehydrogenase; E3; 4 trimethylaminobutyraldehyde dehydrogenase; AL9A1_HUMAN; aldehyde dehydrogenase (NAD+); Aldehyde dehydrogenase 9A1; Aldehyde dehydrogenase E3 isozyme; Aldehyde dehydrogenase family 9 member A1; ALDH4; ALDH7; ALDH9; Gamma aminobutyraldehyde dehydrogenase; Gamma-aminobutyraldehyde dehydrogenase; R aminobutyraldehyde dehydrogenase; R-aminobutyraldehyde dehydrogenase; TMABADH; OTTHUMP00000032604
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ALDH9A1-454H Recombinant Human ALDH9A1 Protein, GST-tagged Wheat Germ GST
    Human ALDH9A1-61HCL Recombinant Human ALDH9A1 cell lysate N/A
    Human ALDH9A1-6469H Recombinant Human ALDH9A1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Aldh9a1-1360M Recombinant Mouse Aldh9a1 protein, His & T7-tagged E.coli His/T7
    Mouse Aldh9a1-1595M Recombinant Mouse Aldh9a1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat ALDH9A1-624R Recombinant Rat ALDH9A1 Protein Mammalian Cell His

    aldh9a1 involved in several pathways and played different roles in them. We selected most pathways aldh9a1 participated on our site, such as Glycolysis / Gluconeogenesis, Ascorbate and aldarate metabolism, Fatty acid degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with aldh9a1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycolysis / Gluconeogenesis ENO1; TPI1B; DLDH; MINPP1A; ALDOCA; HK2; LDHAL6A; GPI1; ADH1; ALDOAA
    Ascorbate and aldarate metabolism UGT1A2; GULO; UGT1A7C; RGN; ALDH3A2A; UGT1A6; ALDH9A1A.1; ALDH2.2; UGT1A6B; UGT2B7
    Fatty acid degradation ADH6; HADH; ACADS; ADH1; ACSL4B; GCDH; CYP4A10; ACOX3; HADHA; CPT1C
    Valine, leucine and isoleucine degradation DLDH; BCKDHB; MCCC2; ACADSB; IL4I1; HADHA; ACAA1; HADH; OXCT1; HIBADH
    Lysine degradation MLL5; PLOD3; ALDH2.1; HADH; OGDHL; ALDH3A2; DOT1L; ALDH2.2; GLT25D1; ACAT1
    Arginine and proline metabolism ALDH2; PYCRL; ALDH3A2; SRM; P4HA1; NOS2B; CKM; SAT1; GOT1; PRODH2
    Histidine metabolism AOC1; ALDH9A1A.1; FTCD; ALDH9A1; ALDH2.1; HDC; ALDH1B1; ALDH3B2; MAOA; HAL
    Tryptophan metabolism HADHA; GCDHA; CYP2F1; INMT; AOX1; CCBL2; CYP1A; CYP4F12; TPH1B; IL4I1
    beta-Alanine metabolism ALDH3B1; ALDH3A2; ALDH3A2A; GAD2; ALDH2.2; GAD1B; MLYCD; ACADM; ALDH3A1; HIBCH
    Glycerolipid metabolism DGKQ; ALDH9A1A.1; LPL; DGAT1; CEL.1; LPIN3; AGK; PPAP2C; AGPAT1; PPAP2A
    Pyruvate metabolism LDHAL6B; ME3; ALDH3A2; PKMB; MPC1; ACAT2; ACYP1; ackA; ACACB; DLAT
    Metabolic pathways FOLH1; GALC; ATP6V0A2B; ATP5G3; NME2; NT5C2B; DPYS; MSMO1; PPAP2CB; PLCH2

    aldh9a1 has several biochemical functions, for example, 1-pyrroline dehydrogenase activity, 3-chloroallyl aldehyde dehydrogenase activity, 4-trimethylammoniobutyraldehyde dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by aldh9a1 itself. We selected most functions aldh9a1 had, and list some proteins which have the same functions with aldh9a1. You can find most of the proteins on our site.

    Function Related Protein
    1-pyrroline dehydrogenase activity ALDH9A1
    3-chloroallyl aldehyde dehydrogenase activity ALDH3A2; ALDH3B2; ALDH3A2A; ALDH3B1; ALDH9A1; ALDH1A1; ALDH2.1; Aldh1a7; ALDH3A1; ALDH3A2B
    4-trimethylammoniobutyraldehyde dehydrogenase activity ALDH9A1B; ALDH9A1; ALDH9A1A.1
    aldehyde dehydrogenase (NAD) activity ALDH1L2; ALDH3A2A; ALDH1L1; ALDH3B2; ALDH8A1; ALDH3A2; ALDH9A1B; ALDH1A1; ALDH3A2B; ALDH9A1
    aminobutyraldehyde dehydrogenase activity ALDH9A1B; ALDH9A1; ALDH9A1A.1

    aldh9a1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with aldh9a1 here. Most of them are supplied by our site. Hope this information will be useful for your research of aldh9a1.

    HLA-B; USP46; TNIP3; DDA1; flgH1; GABARAPL1

    Yang, Y; Zhou, W; et al. NEK2 mediates ALDH1A1-dependent drug resistance in multiple myeloma. ONCOTARGET 5:11986-11997(2014).
    Li, XS; Xu, Q; et al. ALDH1A1 overexpression is associated with the progression and prognosis in gastric cancer. BMC CANCER 14:-(2014).

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