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Official Full Name adaptor-related protein complex 3, sigma 1 subunit
Background AP-3 complex subunit sigma-1 is a protein that in humans is encoded by the AP3S1 gene.
Synonyms AP3S1; adaptor-related protein complex 3, sigma 1 subunit; CLAPS3; AP-3 complex subunit sigma-1; small 3; Adapter-related protein complex 3 sigma-1 subunit; Adaptor-related protein complex 3; AP-3 complex sigma-3A subunit; AP-3 complex subunit sigma-3A; AP3S1_HUMAN; Clathrin associated/assembly/adapter protein small 3; Clathrin-associated/assembly/adapter protein; Sigma-3A-adaptin; Sigma-adaptin 3a; Sigma3A; Sigma3A-adaptin; clathrin-associated/assembly/adapter protein, small 3; clathrin-associated/assembly/adaptor protein, small 3 (22kD)
    • Species :
    • Chicken
    • Human
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human AP3S1-364H Recombinant Human adaptor-related protein complex 3, sigma 1 subunit, His-tagged E.coli His
    Human AP3S1-659H Recombinant Human AP3S1 protein, GST-tagged Wheat Germ GST
    Human AP3S1-8808HCL Recombinant Human AP3S1 293 Cell Lysate HEK293 N/A
    Chicken AP3S1-1723C Recombinant Chicken AP3S1 Mammalian Cell His
    Zebrafish AP3S1-1494Z Recombinant Zebrafish AP3S1 Mammalian Cell His

    AP3S1 involved in several pathways and played different roles in them. We selected most pathways AP3S1 participated on our site, such as Clathrin derived vesicle budding, Golgi Associated Vesicle Biogenesis, Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with AP3S1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Clathrin derived vesicle budding TBC1D8B; TFR1B; NECAP1; AP3S1; FTH1A; CTSZ; HIP1RB; PICALMB; NAPAB; HIP1R
    Golgi Associated Vesicle Biogenesis PICALM; FTH1B; AP1S3A; AP1M2; AP3S1; FTH1A; BLOC1S6; NAPAA; TPD52; BLOC1S4
    Membrane Trafficking PPP6C; SEC16B; PICALM; NAPAB; GJA4; EXOC1; CLVS2; COPG; FTH1B; TRAPPC6A
    Vesicle-mediated transport STXBP3; HYOU1; HIP1RB; SNX9B; MYO6B; PICALMA; CX30.3; RAB10; PUM1; TERFA
    trans-Golgi Network Vesicle Budding HIP1RB; PICALMA; TCEAL4; AP3S1; AP4B1; TPD52L1; BLOC1S6; FTH1B; SH3D19; DTNBP1

    AP3S1 has several biochemical functions, for example, protein binding, protein transporter activity, transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AP3S1 itself. We selected most functions AP3S1 had, and list some proteins which have the same functions with AP3S1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding BUD13; FUT11; TUBB4A; HNF1B; ARL11; ICAM3; HIST1H2AL; PTCH1; CDC6; ADI1
    protein transporter activity IPO7; AP2A2; AP1B1; VPS35; COX18; ZFYVE16; L7RN6; AP1S3; XPO1; KPNA4
    transporter activity SLC2A15A; AP4B1; AQP12B; SLC37A4B; CRABP2B; SLCO1F3; APODA.2; SLC12A10.3; ABCA13; AP1S2

    AP3S1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AP3S1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AP3S1.

    pi3p; Mast3; ZWINT; CD14; Cdk1; Kif4; EMC2; Tmed10; KIAA1107; EPB41L3; PCDHB15

    Stratta, P; Merlotti, G; et al. Calcium-sensing-related gene mutations in hypercalcaemic hypocalciuric patients as differential diagnosis from primary hyperparathyroidism: detection of two novel inactivating mutations in an Italian population. NEPHROLOGY DIALYSIS TRANSPLANTATION 29:1902-1909(2014).
    Kim, YA; Choi, HJ; et al. Replication of Caucasian loci associated with bone mineral density in Koreans. OSTEOPOROSIS INTERNATIONAL 24:2603-2610(2013).

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