AP3S1
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Official Full Name
adaptor-related protein complex 3, sigma 1 subunit -
Overview
AP-3 complex subunit sigma-1 is a protein that in humans is encoded by the AP3S1 gene. -
Synonyms
AP3S1;adaptor-related protein complex 3, sigma 1 subunit;CLAPS3;AP-3 complex subunit sigma-1;small 3;Adapter-related protein complex 3 sigma-1 subunit;Adaptor-related protein complex 3;AP-3 complex sigma-3A subunit;AP-3 complex subunit sigma-3A;AP3S1_HUMAN;Clathrin associated/assembly/adapter protein small 3;Clathrin-associated/assembly/adapter protein;Sigma-3A-adaptin;Sigma-adaptin 3a;Sigma3A;Sigma3A-adaptin;clathrin-associated/assembly/adapter protein, small 3;clathrin-associated/assembly/adaptor protein, small 3 (22kD)
Recombinant Proteins
- Zebrafish
- Chicken
- Human
- Rat
- Mammalian Cells
- E.coli
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| AP3S1-1494Z | Recombinant Zebrafish AP3S1 | Mammalian Cells | Zebrafish | His |
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| AP3S1-1723C | Recombinant Chicken AP3S1 | Mammalian Cells | Chicken | His |
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| AP3S1-364H | Recombinant Human adaptor-related protein complex 3, sigma 1 subunit, His-tagged | E.coli | Human | His | 1-193 a.a. |
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| AP3S1-659H | Recombinant Human AP3S1 protein, GST-tagged | Wheat Germ | Human | GST |
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| AP3S1-8808HCL | Recombinant Human AP3S1 293 Cell Lysate | HEK293 | Human | Non |
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| AP3S1-1043HF | Recombinant Full Length Human AP3S1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 193 amino acids |
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| AP3S1-191H | Recombinant Human AP3S1 Protein, His-tagged | E.coli | Human | His | Met1-Lys193 |
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| Ap3s1-192R | Recombinant Rat Ap3s1 Protein, His-tagged | E.coli | Rat | His | Met1-Arg162 |
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Involved Pathway
AP3S1 involved in several pathways and played different roles in them. We selected most pathways AP3S1 participated on our site, such as Clathrin derived vesicle budding,Golgi Associated Vesicle Biogenesis,Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with AP3S1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Golgi Associated Vesicle Biogenesis | NECAP1,NAPAA,AP1S1,SH3D19,HIP1R,FTH1A,NAPAB,CNO,PUM1,CLINT1 |
| Vesicle-mediated transport | CX27.5,DNASE2,TRAPPC2,ANKRD28,SH3D19,PPP6R3,HYOU1,PLDN,PICALMB,TFR1B |
| Membrane Trafficking | SNX9B,RALAB,PUM1,TGOLN2,TFR1B,TRAPPC2L,TRAPPC2,PICALMB,TRAPPC5,GJA4 |
| Clathrin derived vesicle budding | NAPAB,TPD52L1,SNAPIN,BLOC1S4,AP1B1,AP1G1,PLDN,TPD52,CLVS1,FTH1B |
| trans-Golgi Network Vesicle Budding | SNAPIN,TPD52,CLINT1,DTNBP1B,SNX9A,TCEAL4,BLOC1S1,SNX9B,BLOC1S3,PLDN |
| Lysosome | CTSE,HYAL1,AP4S1,CTSZ,GALCB,ACP5B,CTSBB,SUMF1,CD164,PLA2G15 |
Protein Function
AP3S1 has several biochemical functions, for example, protein binding,protein transporter activity,transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AP3S1 itself. We selected most functions AP3S1 had, and list some proteins which have the same functions with AP3S1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | BMPR1B,IGF2BP2,ZNF187,PCDH18,MS4A12,DDX6,CHMP2A,COL10A1,L3MBTL1,FAM96B |
| protein transporter activity | TNPO1,TNPO3,TIMM10,KPNA4,AP4S1,RANGRF,AP4B1,AP2S1,KPNB1,TMCO6 |
| transporter activity | FABP11A,SLC2A15A,IGF2R,SYPL2B,FABP2,SLC15A4,SLC6A18,FABP4,SLC2A8,ABCB8 |
Interacting Protein
AP3S1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AP3S1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AP3S1.
pi3p;Mast3;ZWINT;CD14;Cdk1;Kif4;EMC2;Tmed10;KIAA1107;EPB41L3;PCDHB15
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References
- Kim, YA; Choi, HJ; et al. Replication of Caucasian loci associated with bone mineral density in Koreans. OSTEOPOROSIS INTERNATIONAL 24:2603-2610(2013).
- Stratta, P; Merlotti, G; et al. Calcium-sensing-related gene mutations in hypercalcaemic hypocalciuric patients as differential diagnosis from primary hyperparathyroidism: detection of two novel inactivating mutations in an Italian population. NEPHROLOGY DIALYSIS TRANSPLANTATION 29:1902-1909(2014).
