AP3S1
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Official Full Name
adaptor-related protein complex 3, sigma 1 subunit
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Overview
AP-3 complex subunit sigma-1 is a protein that in humans is encoded by the AP3S1 gene. -
Synonyms
AP3S1; adaptor-related protein complex 3, sigma 1 subunit; CLAPS3; AP-3 complex subunit sigma-1; small 3; Adapter-related protein complex 3 sigma-1 subunit; Adaptor-related protein complex 3; AP-3 complex sigma-3A subunit; AP-3 complex subunit sigma-3A; AP3S1_HUMAN; Clathrin associated/assembly/adapter protein small 3; Clathrin-associated/assembly/adapter protein; Sigma-3A-adaptin; Sigma-adaptin 3a; Sigma3A; Sigma3A-adaptin; clathrin-associated/assembly/adapter protein, small 3; clathrin-associated/assembly/adaptor protein, small 3 (22kD);
- Recombinant Proteins
- Cell & Tissue Lysates
- Chicken
- Human
- Rat
- Zebrafish
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- Non
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | AP3S1-364H | Recombinant Human adaptor-related protein complex 3, sigma 1 subunit, His-tagged | E.coli | His | 1-193 | |
Human | AP3S1-659H | Recombinant Human AP3S1 protein, GST-tagged | Wheat Germ | GST | ||
Human | AP3S1-8808HCL | Recombinant Human AP3S1 293 Cell Lysate | HEK293 | Non | ||
Human | AP3S1-191H | Recombinant Human AP3S1 Protein, His-tagged | E.coli | His | Met1-Lys193 | |
Human | AP3S1-1043HF | Recombinant Full Length Human AP3S1 Protein, GST-tagged | In Vitro Cell Free System | GST | 193 amino acids | |
Rat | Ap3s1-192R | Recombinant Rat Ap3s1 Protein, His-tagged | E.coli | His | Met1-Arg162 | |
Zebrafish | AP3S1-1494Z | Recombinant Zebrafish AP3S1 | Mammalian Cell | His | ||
Chicken | AP3S1-1723C | Recombinant Chicken AP3S1 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
AP3S1 involved in several pathways and played different roles in them. We selected most pathways AP3S1 participated on our site, such as Clathrin derived vesicle budding, Golgi Associated Vesicle Biogenesis, Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with AP3S1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Clathrin derived vesicle budding | HIP1RB;TGOLN2;APPA;SNX9A;AP1S3A;GAK;CLVS1;NAPAB;NAPAA |
Golgi Associated Vesicle Biogenesis | AP1S1;NAPAA;PPIAL4A;TPD52;TPD52L1;DTNBP1B;AP1M2;AP1G1;SNAPIN |
Lysosome | AP3B1;ATP6V0C;ATP6V0D2;HEXB;ARSB;LAMP3;SORT1A;HEXA;ACP5 |
Membrane Trafficking | TERFA;EXOC8;AP4B1;PICALMA;SCFD1;RAB10;SNX9;GJA4;BLOC1S4 |
Vesicle-mediated transport | CNO;GJB4;GJA5;SNAPIN;GAK;PPP6R3;TPD52L1;GJB7;HIP1R |
trans-Golgi Network Vesicle Budding | SNAPIN;SNX9;CLVS1;TGOLN2;CLINT1;TPD52L1;CPD;SH3D19;DTNBP1B |
AP3S1 has several biochemical functions, for example, protein binding, protein transporter activity, transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AP3S1 itself. We selected most functions AP3S1 had, and list some proteins which have the same functions with AP3S1. You can find most of the proteins on our site.
Function | Related Protein |
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protein binding | PARP2;ZNF434;NR2F1;SRPK3;MAGEH1;KRT17;WDR61;IL23;FIBCD1 |
protein transporter activity | MLC1;EIF4ENIF1;IPO7;VPS26B;ITGB1BP1;SEC61G;RUFY1;SEC62;AP1S3A |
transporter activity | AP3D1;SLC2A13B;SLCO1B2;TMEM184A;SLC5A6A;FABP7;ASNA1;STEAP2;AQP8A.1 |
AP3S1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AP3S1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AP3S1.
pi3p; Mast3; ZWINT; CD14; Cdk1; Kif4; EMC2; Tmed10; KIAA1107; EPB41L3; PCDHB15
Research Area
Related articles
- Reviews
- Q&As
Customer Reviews (4)
Write a reviewReproducibility of AP3S1 is very good, which greatly reduces experimental error and allows me to evaluate experimental results more accurately.
With short half-life and high clearance characteristics, it has higher potential in drug development and is expected to become a new generation of therapeutic drugs.
Stability of AP3S1 is very good, and a variety of experimental operations can be performed without worrying about changes and effects on its performance.
Resolution in Western blot is high, which can distinguish similar protein molecular weights.
Q&As (10)
Ask a questionBased on the results and therapeutic potential of existing studies, the AP3S1 is promising, but further experiments are needed to confirm its efficacy and safety.
There are currently no reports of indications restricting the use of AP3S1 , but specific treatment options need to be determined based on the characteristics of the disease.
The specific choice of dose and route of administration depends on the specific disease and treatment regimen, and further research is needed to determine the optimal dose and method of administration.
AP3S1 has been implicated in the repair of error damage, immune regulation and anti-tumor response.
There have been no definitive reports of side effects, but more clinical trials are needed to assess the potential risks.
There is a lack of large-scale clinical trial results compared to other treatments, so it is not possible to definitively assess their relative effectiveness.
A number of companies and research institutions are currently conducting research related to AP3S1 s, including pharmaceutical companies, university laboratories and scientific research institutions.
AP3S1 has potential applications in immunotherapy, DNA repair therapy and tumor targeting therapy.
Clinical trials, cell culture experiments, animal models, and molecular biological methods can be used to evaluate the therapeutic effect of AP3S1 .
Current studies have shown that the AP3S1 has a potentially important role in the treatment of many diseases, and further studies are currently being conducted to explore its mechanisms and applications.
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