AP4M1 Protein

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AP4M1

Official Full Name	adaptor-related protein complex 4, mu 1 subunit
Background	This gene encodes a subunit of the heterotetrameric AP-4 complex. The encoded protein belongs to the adaptor complexes medium subunits family. This AP-4 complex is involved in the recognition and sorting of cargo proteins with tyrosine-based motifs from the trans-golgi network to the endosomal-lysosomal system.
Synonyms	AP4M1; adaptor-related protein complex 4, mu 1 subunit; AP-4 complex subunit mu-1; adaptor related protein complex AP 4 mu4 subunit; AP 4 adapter complex mu subunit; mu subunit of AP 4; MU 4; mu adaptin related protein 2; MU ARP2; Adaptor related protein complex 4 mu 1 subunit; Adaptor related protein complex AP4 mu4 subunit; Adaptor-related protein complex AP-4, mu 1; AP 4 complex subunit mu 1; AP4 adapter complex mu subunit; AP4 complex subunit mu 1; Ap4m4; CPSQ3; MU4; Mu4-adaptin; MUARP 2; MUARP2; OTTHUMP00000206506; OTTHUMP00000206588; OTTHUMP00000206591; OTTHUMP00000206630; OTTHUMP00000206943; OTTHUMP00000206944; mu subunit of AP-4; mu-adaptin-related protein 2; mu-adaptin-related protein-2; adapter-related protei; MU-4; MU-ARP2

Species :
Chicken
Human
Mouse
Rat
Zebrafish

Source :
E.coli
E.Coli or Yeast
Mammalian Cell
Wheat Germ

Tag :
GST
His
N/A
N-His

Species	Cat.#	Product name	Source (Host)	Tag
Human	AP4M1-3544H	Recombinant Human AP4M1, His-tagged	E.Coli or Yeast	His
Human	AP4M1-663H	Recombinant Human AP4M1 protein, GST-tagged	Wheat Germ	GST
Mouse	AP4M1-1752M	Recombinant Mouse AP4M1 Protein	Mammalian Cell	His
Rat	AP4M1-704R	Recombinant Rat AP4M1 Protein	Mammalian Cell	His
Chicken	AP4M1-6698C	Recombinant Chicken AP4M1	Mammalian Cell	His
Zebrafish	AP4M1-779Z	Recombinant Zebrafish AP4M1	Mammalian Cell	His
Human	AP4M1-88HCL	Recombinant Human AP4M1 cell lysate		N/A
Mouse	Ap4m1-196M	Recombinant Mouse Ap4m1 Protein, His-tagged	E.coli	N-His

Involved Pathway Protein Function Interacting Protein AP4M1 Related Articles

AP4M1 involved in several pathways and played different roles in them. We selected most pathways AP4M1 participated on our site, such as Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with AP4M1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Lysosome	ATP6V0A1; ATP6V0A2; ASAH1B; Ctsl; CTSLA; FAM49BA; TCEAL4; NPC1; CLN5; ACP2

AP4M1 has several biochemical functions, for example, protein binding, transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AP4M1 itself. We selected most functions AP4M1 had, and list some proteins which have the same functions with AP4M1. You can find most of the proteins on our site.

Function	Related Protein
protein binding	BIN2; FOXP2; HSPA5; ECE2; SOX9A; ZNF350; EPN3; NRP1; SNX17; EGLN3
transporter activity	SLC23A1; SLC4A8; HIAT1; FABP5; SLC25A38A; LCN2; ABCA4A; AQP10B; SLCO1F2; SLC13A2

AP4M1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AP4M1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AP4M1.

USP47; tax; ZBTB22; CHTF8; DDX52; b4dnw0_human; SF3B2; H3F3B; CBX4; LCMT2; RALA; IMPDH2; HMGA1; CDK11B; AKT2; GALNT2; NPAT

Abdollahpour, H; Alawi, M; et al. An AP4B1 frameshift mutation in siblings with intellectual disability and spastic tetraplegia further delineates the AP-4 deficiency syndrome. EUROPEAN JOURNAL OF HUMAN GENETICS 23:256-259(2015).

Jameel, M; Klar, J; et al. A novel AP4M1 mutation in autosomal recessive cerebral palsy syndrome and clinical expansion of AP-4 deficiency. BMC MEDICAL GENETICS 15:-(2014).

AP4M1

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AP4M1

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