AP4M1
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Official Full Name
adaptor-related protein complex 4, mu 1 subunit -
Overview
This gene encodes a subunit of the heterotetrameric AP-4 complex. The encoded protein belongs to the adaptor complexes medium subunits family. This AP-4 complex is involved in the recognition and sorting of cargo proteins with tyrosine-based motifs from the trans-golgi network to the endosomal-lysosomal system. -
Synonyms
AP4M1;adaptor-related protein complex 4, mu 1 subunit;AP-4 complex subunit mu-1;adaptor related protein complex AP 4 mu4 subunit;AP 4 adapter complex mu subunit;mu subunit of AP 4;MU 4;mu adaptin related protein 2;MU ARP2;Adaptor related protein complex 4 mu 1 subunit;Adaptor related protein complex AP4 mu4 subunit;Adaptor-related protein complex AP-4, mu 1;AP 4 complex subunit mu 1;AP4 adapter complex mu subunit;AP4 complex subunit mu 1;Ap4m4;CPSQ3;MU4;Mu4-adaptin;MUARP 2;MUARP2;OTTHUMP00000206506;OTTHUMP00000206588;OTTHUMP00000206591;OTTHUMP00000206630;OTTHUMP00000206943;OTTHUMP00000206944;mu subunit of AP-4;mu-adaptin-related protein 2;mu-adaptin-related protein-2;adapter-related protei;MU-4;MU-ARP2
Recombinant Proteins
- Mouse
- Human
- Chicken
- Rat
- Zebrafish
- Mammalian Cells
- E.Coli/Yeast
- Wheat Germ
- In Vitro Cell Free System
- E.coli
- HEK293
- His
- GST
- Non
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| AP4M1-1752M | Recombinant Mouse AP4M1 Protein | Mammalian Cells | Mouse | His |
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| AP4M1-3544H | Recombinant Human AP4M1, His-tagged | E.Coli/Yeast | Human | His | 453 |
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| AP4M1-663H | Recombinant Human AP4M1 protein, GST-tagged | Wheat Germ | Human | GST |
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| AP4M1-6698C | Recombinant Chicken AP4M1 | Mammalian Cells | Chicken | His |
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| AP4M1-704R | Recombinant Rat AP4M1 Protein | Mammalian Cells | Rat | His |
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| AP4M1-779Z | Recombinant Zebrafish AP4M1 | Mammalian Cells | Zebrafish | His |
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| AP4M1-88HCL | Recombinant Human AP4M1 cell lysate | Human | Non |
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| AP4M1-1095HF | Recombinant Full Length Human AP4M1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 453 amino acids |
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| Ap4m1-196M | Recombinant Mouse Ap4m1 Protein, His-tagged | E.coli | Mouse | His | Met1-Val208 |
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| AP4M1-360R | Recombinant Rat AP4M1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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| AP4M1-360R-B | Recombinant Rat AP4M1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| AP4M1-609M | Recombinant Mouse AP4M1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| AP4M1-609M-B | Recombinant Mouse AP4M1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
AP4M1 involved in several pathways and played different roles in them. We selected most pathways AP4M1 participated on our site, such as Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with AP4M1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Lysosome | CTSZ,FAM49BA,AP3M1,PSAPL1,GNPTAB,ATP6AP1B,AP4E1,CTSM,AP3S1,GLA |
Protein Function
AP4M1 has several biochemical functions, for example, protein binding,transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AP4M1 itself. We selected most functions AP4M1 had, and list some proteins which have the same functions with AP4M1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transporter activity | LCN5,SLCO2B1,SEC22A,SCARB1,SYPB,SLC4A4A,TMEM184B,RLBP1B,ABCC1,SYPL2 |
| protein binding | MYLIP,PPAP2B,GHRHR,FHL2,IL2RG,IL2RB,KIAA1530,FAM32A,TOM1,GPRC5A |
Interacting Protein
AP4M1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AP4M1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AP4M1.
USP47;tax;ZBTB22;CHTF8;DDX52;b4dnw0_human;SF3B2;H3F3B;CBX4;LCMT2;RALA;IMPDH2;HMGA1;CDK11B;AKT2;GALNT2;NPAT
Resources
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References
- Jameel, M; Klar, J; et al. A novel AP4M1 mutation in autosomal recessive cerebral palsy syndrome and clinical expansion of AP-4 deficiency. BMC MEDICAL GENETICS 15:-(2014).
- Abdollahpour, H; Alawi, M; et al. An AP4B1 frameshift mutation in siblings with intellectual disability and spastic tetraplegia further delineates the AP-4 deficiency syndrome. EUROPEAN JOURNAL OF HUMAN GENETICS 23:256-259(2015).
