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Official Full Name ATPase, Na+/K+ transporting, alpha 1 polypeptide
Background This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
Synonyms ATP1A1; ATPase, Na+/K+ transporting, alpha 1 polypeptide; sodium/potassium-transporting ATPase subunit alpha-1; sodium pump 1; Na+/K+ ATPase 1; Na,K-ATPase alpha-1 subunit; sodium pump subunit alpha-1; Na+, K+ ATPase alpha subunit; Na(+)/K(+) ATPase alpha
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rabbit
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ATP1A1-10004H Recombinant Human ATP1A1, His-tagged E.coli His
    Human ATP1A1-293H Recombinant Human ATP1A1 protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human ATP1A1-460H Recombinant Human ATP1A1 Protein, His-tagged E.coli His
    Human ATP1A1-8613HCL Recombinant Human ATP1A1 293 Cell Lysate HEK293 N/A
    Mouse ATP1A1-2113M Recombinant Mouse ATP1A1 Protein Mammalian Cell His
    Rat ATP1A1-852R Recombinant Rat ATP1A1 Protein Mammalian Cell His
    Rhesus Macaque ATP1A1-446R Recombinant Rhesus monkey ATP1A1 Protein, His-tagged Mammalian Cell His
    Rabbit ATP1A1-461R Recombinant Rabbit ATP1A1 Protein, His-tagged E.coli His
    Chicken ATP1A1-7070C Recombinant Chicken ATP1A1 Mammalian Cell His

    atp1a1 involved in several pathways and played different roles in them. We selected most pathways atp1a1 participated on our site, such as cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with atp1a1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    cGMP-PKG signaling pathway FXYD2; GUCY1B3; SLC25A6; ATP2B4; GTF2I; VDAC3; PIK3R2; MEF2A; ITPR3; BAD
    cAMP signaling pathway FSHR; GRIN3A; HHIP; ACOX3; PDE3A; AMH; GRIA3; ATP1A1; FOS; GLI3
    Cardiac muscle contraction CACNB4; TNNT2; COX7A2A; ATP1A2; ATP2A2; TNNI3; TNNC1A; COX7A3; TNNC1; CACNG4
    Adrenergic signaling in cardiomyocytes ADRB2B; CALM1A; PPP1R1A; CACNB2; MAPK12B; GNAI2; AKT2; ATP1B1B; ADRA1D; CALML3
    Insulin secretion KCNMA1; ATP1B2; ATP1B4; KCNN4; PDX1; CREB5; GCG; KCNMB3; PLCB1; INS2
    Thyroid hormone synthesis CREB5; GPX1; TG; GPX8; ATP1A2; LRP2; PRKCB; GPX5; GPX2; CREB3L3
    Thyroid hormone signaling pathway PLN; ATP1A4; PIK3CD; PRKCG; SLC9A1; PRKACA; SIN3A; MDM2; HDAC2; NOTCH4
    Aldosterone-regulated sodium reabsorption SLC9A3R2; SFN; PIK3CA; FXYD2; MAPK1; PIK3R5; INS; NR3C2; PIK3CB; ATP1B1
    Endocrine and other factor-regulated calcium reabsorption BDKRB2; KLK1B1; PRKACB; ATP1B3; KLK1B3; DNM3; KL; KLK1B5; PRKCG; ATP1A3
    Proximal tubule bicarbonate reclamation SLC25A10; SLC9A3; ATP1A3; ATP1A2; GLUD2; ATP1A1; ATP1B4; GLS; SLC4A4; GLUD1
    Salivary secretion ITPR3; VAMP2; ATP1B4; MUC5B; ATP1B2; ATP1A4; CD38; AMY1A; CALM3; Slc4a2
    Gastric acid secretion CAMK2G; CALML3; ATP4A; PRKACB; CCKBR; KCNJ15; KCNK10; KCNJ10; ATP1B3; CALM2
    Pancreatic secretion RYR2; PLA2G2F; CLCA3; PRKCG; CPB2; Car2; PRSS3; AMY2A4; RAP1B; RAP1A
    Carbohydrate digestion and absorption G6PC; PLCB2; SLC5A1; PIK3R1; ATP1B3; PIK3R2; HK1; GNAT3; SLC2A2; HKDC1
    Protein digestion and absorption SLC16A10; KCNQ1; CPB2; CPA1; COL18A1; ATP1B3; MEP1B; KCNJ13; CELA3B; COL15A1
    Bile secretion ATP1A3; ATP1B2; SLCO1A4; OSTA; ATP1A4; ABCB11; SLC51B; NCEH1; SULT2A1; AQP4
    Mineral absorption MT2A; SLC9A3; S100G; SLC11A1; MT1M; CYBRD1; ATOX1; SLC8A1; Trf; HEPH

    atp1a1 has several biochemical functions, for example, ADP binding, ATP binding, ankyrin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by atp1a1 itself. We selected most functions atp1a1 had, and list some proteins which have the same functions with atp1a1. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding STK4; EHD4; NLK1; DGKAA; RAD54B; TAP2; PKM; P2RX4B; SMG1; FARSA
    ankyrin binding SCN5A; SLC4A1; RHBG; SPTBN1; KCNJ11; OBSCN; KCNQ2; PTBP3; RHCG; NRCAM
    chaperone binding HSPD1; TSC1; VWF; BAG1; FGB; DNAJA3A; PFDN6; DNAJB2; UBL4A; DNAJA2
    phosphatase activity CTDSPLA; ALPI.2; DUSP28; PTPN23A; C12orf5; DUSP19A; PHOSPHO2; MINPP1B; PTPRDB; DUSP11
    phosphatidylinositol 3-kinase binding CORO1A; FYN; TYRO3; CALM1; IGF1R; CALM3; IRS4; IGF1RB; INSRB; HCST
    potassium ion binding PKM; ATP1A1; SLC24A4; SLC24A2; KCNA4; SLC24A1; SLC24A4A; KCNJ11; PKM2; PDXK
    protein binding TLR3; CST2; JUP; ACTA1; SF3A1; STEAP3; FTH1; NHLRC2; APOO; IFT122
    protein domain specific binding ICAL1; CHMP2B; GABRR2; SKI; MRPS31; CNTLN; CASP2; RAB27A; HNRNPM; DIXDC1
    protein kinase binding PXN; JTB; SPRED2; FZD5; CHRNA7; LLGL1; POLA1; KCNH1; TSKS; FBXO5
    sodium ion binding SCN9A; ATP1A1; SLC24A2; SLC34A2; SLC24A4A; SLC24A4; PDXK; SLC24A5; SLC24A1; CAPN3
    sodium:potassium-exchanging ATPase activity ATP12A; ATP1A1A.5; ATP1A1; ATP1A2; ATP1A1B; ATP1B3; ATP1A1A.3; ATP1A1A.1; ATP1A3; ATP1A4
    contributes_to sodium:potassium-exchanging ATPase activity ATP1A2; ATP1A1; ATP1B2; ATP1B1; ATP1B3
    steroid hormone binding ATP1A3; NR3C1; GPR30; ATP1A2; ATP1A1; ESR2A; ESR2B

    atp1a1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with atp1a1 here. Most of them are supplied by our site. Hope this information will be useful for your research of atp1a1.

    TPT1; ERBB2; GTF2F2; TNFRSF1A; TNFRSF1B; Tpt1; TRADD; SMAD2; NDRG1; SNX6; SNAPIN; EZH2; 15-deoxy-delta(12,14

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