ATP1A1

  • Official Full Name

    ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • Overview

    This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
  • Synonyms

    ATP1A1;ATPase, Na+/K+ transporting, alpha 1 polypeptide;sodium/potassium-transporting ATPase subunit alpha-1;sodium pump 1;Na+/K+ ATPase 1;Na,K-ATPase alpha-1 subunit;sodium pump subunit alpha-1;Na+, K+ ATPase alpha subunit;Na(+)/K(+) ATPase alpha

Recombinant Proteins

  • Human
  • Rabbit
  • Mouse
  • Rhesus macaque
  • Chicken
  • Rat
  • E.coli
  • Mammalian Cells
  • HEK293
  • His
  • DDK
  • Myc
  • Non
  • Avi
  • Fc
  • GST
  • Flag
Cat.# Product name Source (Host) Species Tag Protein Length Price
ATP1A1-10004H Recombinant Human ATP1A1, His-tagged E.coli Human His 346-680a.a.
ATP1A1-460H Recombinant Human ATP1A1 Protein, His-tagged E.coli Human His His493~Ala660
ATP1A1-461R Recombinant Rabbit ATP1A1 Protein, His-tagged E.coli Rabbit His Thr339~Leu772
ATP1A1-2113M Recombinant Mouse ATP1A1 Protein Mammalian Cells Mouse His
ATP1A1-293H Recombinant Human ATP1A1 protein, MYC/DDK-tagged HEK293 Human DDK&Myc
ATP1A1-446R Recombinant Rhesus monkey ATP1A1 Protein, His-tagged Mammalian Cells Rhesus macaque His
ATP1A1-7070C Recombinant Chicken ATP1A1 Mammalian Cells Chicken His
ATP1A1-852R Recombinant Rat ATP1A1 Protein Mammalian Cells Rat His
ATP1A1-8613HCL Recombinant Human ATP1A1 293 Cell Lysate HEK293 Human Non
ATP1A1-0551H Recombinant Human ATP1A1 Protein (Thr347-Asp680), N-His-tagged E.coli Human His Thr347-Asp680
ATP1A1-275R Recombinant Rhesus Macaque ATP1A1 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
ATP1A1-275R-B Recombinant Rhesus Macaque ATP1A1 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
ATP1A1-301593H Recombinant Human ATP1A1 protein, GST-tagged E.coli Human GST Thr347-Asp680
ATP1A1-379HFL Recombinant Full Length Human ATP1A1 Protein, C-Flag-tagged Mammalian Cells Human Flag Full L.
ATP1A1-399H Recombinant Human ATP1A1 Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
ATP1A1-399H-B Recombinant Human ATP1A1 Protein Pre-coupled Magnetic Beads HEK293 Human
Atp1a1-4353M Recombinant Mouse Atp1a1 protein, His-tagged E.coli Mouse His 341-775aa
ATP1A1-4627H Recombinant Human ATP1A1 protein, His-Myc-tagged E.coli Human His&Myc
ATP1A1-508R Recombinant Rat ATP1A1 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
ATP1A1-508R-B Recombinant Rat ATP1A1 Protein Pre-coupled Magnetic Beads HEK293 Rat
ATP1A1-848M Recombinant Mouse ATP1A1 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
ATP1A1-848M-B Recombinant Mouse ATP1A1 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    ATP1A1 involved in several pathways and played different roles in them. We selected most pathways ATP1A1 participated on our site, such as cGMP-PKG signaling pathway,cAMP signaling pathway,Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP1A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Bile secretion SLC4A4,SLC22A7,SLC10A2,SCARB1,SLC5A1,ATP1A2,KCNN2,CA2,AQP1,ADCY9
    Pancreatic secretion CPB2,CPA1,CLCA2,RAB27B,SCTR,CLCA4,ATP2A2,PLA2G12A,CD38,RAB3D
    Endocrine and other factor-regulated calcium reabsorption ATP1A2,PTH1R,BDKRB2,TRPV5,GNAQ,KL,GNAS,FXYD2,PRKACA,PLCB1
    Gastric acid secretion MYLK4,ATP1A4,SLC9A4,CAMK2B,Slc4a2,ATP1B3,SLC9A1,PRKCG,PRKACA,GNAI1
    Carbohydrate digestion and absorption SI,AMY2A,AKT1,AMY2B,PIK3CA,PIK3R1,ATP1A3,PRKCB,AKT2,FXYD2
    Thyroid hormone signaling pathway PLCB2,ATP1A2,PLCZ1,RXRB,HDAC2,SLC16A2,PIK3R5,PFKFB2,PLCB4,PRKCG
    Aldosterone-regulated sodium reabsorption ATP1B4,PIK3CB,ATP1A2,SCNN1G,SLC9A3R2,PIK3CD,PIK3CA,PIK3R5,PIK3R1,NEDD4L
    Thyroid hormone synthesis ATP1B3,PRKACG,ITPR3,PLCB1,PRKACB,ITPR1,IYD,TSHR,TSHB,CREB3L3
    Proximal tubule bicarbonate reclamation ATP1B3,PCK2,ATP1B2,SLC38A3,MDH1,GLS,SLC9A3,SLC25A10,ATP1A2,CA2

    Protein Function

    ATP1A1 has several biochemical functions, for example, ADP binding,ATP binding,ankyrin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP1A1 itself. We selected most functions ATP1A1 had, and list some proteins which have the same functions with ATP1A1. You can find most of the proteins on our site.

    Function Related Protein
    protein kinase binding SV2A,CCNK,EMP2,GPRC5B,DPYSL2,MAP2K3,SLC12A4,ARHGEF7,ILK,APC
    phosphatase activity SACM1L,CTDSPLB,PTPRJA,DUSP13A,MTMR1B,DUSP27,CTDNEP1,CA3,CTDSPL2A,DUSP10
    sodium ion binding SLC24A2,SLC34A2,SCN9A,SLC24A4,CAPN3,SLC24A4A,PDXK,SLC24A1,SLC24A5
    protein domain specific binding GABRR3,YWHAH,MED12,HMGB2,DYNLL1,CALM2,ARFIP2B,IRS2,EHD2,RUNX2
    chaperone binding GRPEL1,DNAJA3A,ERP29,DLST,TBCC,PFDN6,HES1,BAG3,DNAJC3,BIRC5
    ATP binding OASL,DYNC1H1,KIF12,ATM,ADCY8,ORC4L,HSPA7,CLK4,ATP8B1,PIKFYVE
    ADP binding PRKAG1,VCP,MYO6,PRPS1,MYO18A,P2RY1,PRPS2,GLUD2,GCLC,MYH9
    steroid hormone binding ATP1A3,ESR2A,ATP1A2,ESR2B,NR3C1,GPR30
    potassium ion binding SLC24A4,PKMA,SLC24A1,SLC24A2,KCNJ11,SLC24A5,PKM2,KCNA4,PKMB,SLC24A4A

    Interacting Protein

    ATP1A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP1A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP1A1.

    TPT1;ERBB2;GTF2F2;TNFRSF1A;TNFRSF1B;Tpt1;TRADD;SMAD2;NDRG1;SNX6;SNAPIN;EZH2;15-deoxy-delta(12,14

    Resources

    References

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