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Official Full Name ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
Background This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain E subunit isoforms. Pseudogenes for this gene have been found in the genome.
Synonyms ATP6V1E1; ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1; ATP6E, ATP6V1E, ATPase, H+ transporting, lysosomal (vacuolar proton pump) 31kD , ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E isoform 1; V-type proton ATPase subunit E 1; ATP6E2; P31; Vma4; ATP6E; ATP6V1E; V ATPase 31 kDa subunit; Vacuolar proton pump subunit E 1; OTTHUMP00000065606; OTTHUMP00000196213; OTTHUMP00000214152; OTTHUMP00000214153; V-ATPase, subunit E; V-ATPase subunit E 1; V-ATPase 31 kDa subunit; H+-transporting ATP synthase chain E, vacuolar; H(+)-transporting two-sector ATPase, 31kDa subunit
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Atp6v1e1-673M Recombinant Mouse Atp6v1e1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human ATP6V1E1-10046H Recombinant Human ATP6V1E1, GST-tagged E.coli GST
    Human ATP6V1E1-1006H Recombinant Human ATP6V1E1 protein, GST-tagged Wheat Germ GST
    Human ATP6V1E1-386H Recombinant Human ATP6V1E1, T7-tagged E.coli T7
    Human ATP6V1E1-8580HCL Recombinant Human ATP6V1E1 293 Cell Lysate HEK293 N/A
    Mouse ATP6V1E1-2164M Recombinant Mouse ATP6V1E1 Protein Mammalian Cell His
    Rat ATP6V1E1-893R Recombinant Rat ATP6V1E1 Protein Mammalian Cell His
    Cynomolgus Monkey ATP6V1E1-328C Recombinant Cynomolgus ATP6V1E1 Protein, His-tagged Mammalian Cell His
    Chicken ATP6V1E1-1393C Recombinant Chicken ATP6V1E1 Mammalian Cell His

    atp6v1e1 involved in several pathways and played different roles in them. We selected most pathways atp6v1e1 participated on our site, such as Oxidative phosphorylation, Metabolic pathways, Phagosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with atp6v1e1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Oxidative phosphorylation ATP5S; COX7B2; ATP6V1E1; NDUFB5; UQCR10; ATP5G3A; COX7A1; ATP6V0D2; NDUFC2-KCTD14; ATPV0E2
    Metabolic pathways ST3GAL4; ACSBG1; DPM3; PAFAH1B3; SPHK1; HYAL1; PRODH2; SGMS2; UPRT; SEPHS1
    Phagosome C3A.3; THBS2; TUBB5; HLA-A; MSR1; LAMP2; BLB2; ATP6V1C1B; TUBA3C; DYNC1I2A
    Synaptic vesicle cycle CPLX2; ATP6V0C; SLC17A8; NSF; ATP6V0D1; VAMP2; STX3; SYT1; ATP6V0E2; UNC13C
    Collecting duct acid secretion ATP6V1D; ATP6V0A4; ATP6V0C; ATP6V1G3; ATP6V0A1; ATP4B; ATP6V0D1; ATP6V1E2; ATP6V1G2; TCIRG1
    Vibrio cholerae infection PRKACG; PRKCA; ATP6V0D2; TJP2; ATP6V1C1; ATP6V0A2; PDIA4; ATP6V1H; ATP6V1A; ACTB
    Epithelial cell signaling in Helicobacter pylori infection ATP6V1G1; ATP6V0E1; ATP6V0A1; MAPK12; IKBKB; CXCL1; MAPK9; ATP6V0B; CDC42; ATP6V1C1
    Rheumatoid arthritis ATP6V1D; VEGFA; ATP6V1B1; ATP6V1E2; ATP6V0D2; HLA-DQA2; HLA-DRB5; FOS; ATP6AP1; CXCL1

    atp6v1e1 has several biochemical functions, for example, ATPase binding, hydrogen-exporting ATPase activity, phosphorylative mechanism, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by atp6v1e1 itself. We selected most functions atp6v1e1 had, and list some proteins which have the same functions with atp6v1e1. You can find most of the proteins on our site.

    Function Related Protein
    ATPase binding ATP6V0A2; SNX10; RAB4A; S100A1; NKAIN1; USP25; ATP6V1G3; FXYD7; DRD1; ZNHIT6
    hydrogen-exporting ATPase activity, phosphorylative mechanism ATP6V1G3; ATP6V0D1; ATP6V1E2; ATP6V1G1; ATP6V1C2; ATP6V1C1; ATP6V1E1
    protein binding SNAP29; UBE2W; ZMYND10; SCNN1D; WDR48; WBP11; SULT2B1; KDRL; SHD; PEX11A
    proton-transporting ATPase activity, rotational mechanism ATP6V0C; ATP6V1A; ATP6AP1B; ATP6V0A4; ATP6V1E2; ATP6V1E1B; ATP5A1; ATP6V1E1; ATP5E; ATP6V1B2

    atp6v1e1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with atp6v1e1 here. Most of them are supplied by our site. Hope this information will be useful for your research of atp6v1e1.

    DEDD; ATP6V1G1; ATP6V1G2; XRCC6; MESDC2; pyrH; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; pi3p; ATP6V1A; Rmdn3; Chmp4b; CHMP4B; GOLT1B

    Yang, LS; Xu, XE; et al. iTRAQ-based quantitative proteomic analysis for identification of oligodendroglioma biomarkers related with loss of heterozygosity on chromosomal arm 1p. JOURNAL OF PROTEOMICS 77:480-491(2012).
    Knijnenburg, J; van Bever, Y; et al. A 600 kb triplication in the cat eye syndrome critical region causes anorectal, renal and preauricular anomalies in a three-generation family. EUROPEAN JOURNAL OF HUMAN GENETICS 20:986-989(2012).

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