BRD8

  • Official Full Name

    bromodomain containing 8

  • Overview

    The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator. Three alternatively spliced transcript variants that encode distinct isoforms have been identified.
  • Synonyms

    BRD8; bromodomain containing 8; bromodomain-containing protein 8; p120; SMAP; trCP120; skeletal muscle abundant protein 2; thyroid hormone receptor coactivating protein of 120 kDa; SMAP2;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human BRD8-97H Recombinant Human BRD8 protein, GST-tagged E.coli GST 701-819
Human BRD8-98H Recombinant Human BRD8 protein, His-tagged E.coli His 701-819
Human BRD8-332H Recombinant Human BRD8 Protein, GST-tagged Wheat Germ GST
Human BRD8-25H Recombinant Human BRD8 protein E.coli N/A 701-819 aa
Human BRD8-2782H Recombinant Human BRD8 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human BRD8-2396H Recombinant Human BRD8 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse BRD8-2487M Recombinant Mouse BRD8 Protein Mammalian Cell His
Mouse Brd8-456M Recombinant Mouse Brd8 Protein, His-tagged E.coli His Ala797~Lys951
Mouse BRD8-1087M Recombinant Mouse BRD8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Brd8-1891M Recombinant Mouse Brd8 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse BRD8-1087M-B Recombinant Mouse BRD8 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish BRD8-12045Z Recombinant Zebrafish BRD8 Mammalian Cell His
Chicken BRD8-1300C Recombinant Chicken BRD8 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • BRD8 Related Research Area

BRD8 involved in several pathways and played different roles in them. We selected most pathways BRD8 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, HATs acetylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with BRD8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chromatin modifying enzymesPHF8;PADI4;SAP30L;DNMT3A;KDM3A;ING3;MSL2B;KDM4C;SMARCD1
Chromatin organizationTADA2A;EPC1;PHF21A;BRMS1;PRDM16;KANSL2;EHMT2;KDM2B;ENY2
HATs acetylate histonesKAT7A;C20orf20;EP400;MSL2A;ELP3;VPS72;ACTL6A;YEATS4;RUVBL2

BRD8 has several biochemical functions, for example, protein binding, thyroid hormone receptor activity, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BRD8 itself. We selected most functions BRD8 had, and list some proteins which have the same functions with BRD8. You can find most of the proteins on our site.

Function Related Protein
protein bindingRANBP2;MRPL23;AP1B1;PTPN14;PAGE1;TNNC2;LIG3;ECE2;USP5
thyroid hormone receptor activityNR2F6;NR1D4B;THRAA;THRA;BRD8;NR1D2A;NR1I3;NR1H4;NR1D4A
transcription factor activity, sequence-specific DNA bindingARID4A;TBX18;AHR1A;PBX3B;STAT6;FOXC1A;E2F7;CREB1B;SALL1

BRD8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BRD8 here. Most of them are supplied by our site. Hope this information will be useful for your research of BRD8.

MRGBP; ACTL6A; MORF4L2; EP400; MORF4L1; TRRAP; deoB; SNW1; VPS72; ESR2; CDC5L; RUVBL2; RUVBL1

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