BRD8 Protein


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Official Full Name bromodomain containing 8
Background The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator. Three alternatively spliced transcript variants that encode distinct isoforms have been identified.
Synonyms BRD8; bromodomain containing 8; bromodomain-containing protein 8; p120; SMAP; trCP120; skeletal muscle abundant protein 2; thyroid hormone receptor coactivating protein of 120 kDa; SMAP2
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human BRD8-25H Recombinant Human BRD8 protein E.coli N/A
    Human BRD8-332H Recombinant Human BRD8 Protein, GST-tagged Wheat Germ GST
    Human BRD8-97H Recombinant Human BRD8 protein, GST-tagged E.coli GST
    Human BRD8-98H Recombinant Human BRD8 protein, His-tagged E.coli His
    Mouse BRD8-2487M Recombinant Mouse BRD8 Protein Mammalian Cell His
    Chicken BRD8-1300C Recombinant Chicken BRD8 Mammalian Cell His
    Zebrafish BRD8-12045Z Recombinant Zebrafish BRD8 Mammalian Cell His
    Human BRD8-2396H Recombinant Human BRD8 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human BRD8-2782H Recombinant Human BRD8 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse Brd8-1891M Recombinant Mouse Brd8 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse Brd8-456M Recombinant Mouse Brd8 Protein, His-tagged E.coli His

    BRD8 involved in several pathways and played different roles in them. We selected most pathways BRD8 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, HATs acetylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with BRD8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chromatin modifying enzymes SAP130; JADE1; KIAA1267; KDM4C; SMARCA4; ATF7IP; AEBP2; ELP2; PADI4; SMARCB1
    Chromatin organization ARID4A; SMYD2; SAP130; KIAA1267; SMARCA2; ZZZ3; EP400; KDM2AA; PRMT7; PRMT5
    HATs acetylate histones JADE1; MORF4L2; MORF4L1; TADA2A; MSL3; YEATS4; KAT6A; DMAP1; C17orf81; EPC1

    BRD8 has several biochemical functions, for example, protein binding, thyroid hormone receptor activity, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BRD8 itself. We selected most functions BRD8 had, and list some proteins which have the same functions with BRD8. You can find most of the proteins on our site.

    Function Related Protein
    protein binding DCUN1D5; RABIF; ATL1; BMP2; SLC26A3; NUMA1; VIM; USP28; RNF5; B2M
    thyroid hormone receptor activity NR1H4; THRA; THRAA; NR1D4A; NR4A3; THRB; NR1I3; NR1D2A; NR1D4B; NR2F6
    transcription factor activity, sequence-specific DNA binding HOXB6B; HMGA1B; HOXD10; CITED1; ZNF649; PBX2; ZSCAN20; L3MBTL4; RXRAA; FOXB1A

    BRD8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BRD8 here. Most of them are supplied by our site. Hope this information will be useful for your research of BRD8.


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