• Official Full Name
  • dishevelled-binding antagonist of beta-catenin 1
  • Background
  • The protein encoded by this gene belongs to the dapper family, characterized by the presence of PDZ-binding motif at the C-terminus. It interacts with, and positively regulates dishevelled-mediated signaling pathways during development. Depletion of this mRNA from xenopus embryos resulted in loss of notochord and head structures, and mice lacking this gene died shortly after birth from severe posterior malformations. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
  • Synonyms
  • DACT1; dishevelled-binding antagonist of beta-catenin 1; DPR1; FRODO; HDPR1; DAPPER; THYEX3; DAPPER1; dapper homolog 1; dapper antagonist of catenin 1; heptacellular carcinoma novel gene 3; dapper, antagonist of beta-catenin, homolog 1; hepatocellular carcinoma novel gene 3 protein;
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DACT1 Protein, GST-tagged
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken DACT1
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish DACT1
Source (Host):Species:Human
Product nameRecombinant Human DACT1 293 Cell Lysate

Dact1 Related Articles

Gan, TQ; Tang, RX; et al. Upregulated MiR-1269 in hepatocellular carcinoma and its clinical significance. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE 8:714-721(2015).
Schussel, JL; Kalinke, LP; et al. Expression and epigenetic regulation of DACT1 and DACT2 in oral squamous cell carcinoma. CANCER BIOMARKERS 15:11-17(2015).