• Official Full Name
  • IKBKB interacting protein
  • Background
  • IKK-β is an enzyme that serves as a protein subunit of IκB kinase, which is a component of the cytokine-activated intracellular signaling pathway involved in triggering immune responses. Its activity causes activation of a transcription factor known as Nuclear Transcription factor kappa-B or NF-κB. Activated IKK-β phosphorylates a protein called the inhibitor of NF-κB, IκB (IκBα), which binds NF-κB to inhibit its function. Phosphorylated IκB is degraded via the ubiquitination pathway, freeing NF-κB, and allowing its entry into the nucleus of the cell where it activates various genes involved in inflammation and other immune responses.
  • Synonyms
  • IKBIP; IKBKB interacting protein; inhibitor of nuclear factor kappa-B kinase-interacting protein; FLJ31051; I kappa B kinase interacting protein; IKIP; IKK interacting protein; IKK-interacting protein; IKBKB-interacting protein; i kappa-B kinase-interacti
Source (Host):HEK293Species:Human
Product nameRecombinant Human IKBIP Protein, MYC/DDK-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IKBIP protein, His & T7-tagged
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ikbip protein, His & T7-tagged
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Ikbip protein, His & T7-tagged
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat IKBIP Protein
Source (Host):Species:Human
Product nameRecombinant Human IKBIP 293 Cell Lysate

IKBIP Related Articles

Hennig, EE; Mikula, M; et al. Extracellular matrix and cytochrome P450 gene expression can distinguish steatohepatitis from steatosis in mice. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 18:1762-1772(2014).
Khattak, NA; Mir, A; et al. Computational Analysis of TRAPPC9: Candidate Gene for Autosomal Recessive Non-Syndromic Mental Retardation. CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS 13:699-711(2014).
Cen, H; Zhou, M; et al. Genetic interaction between genes involved in NF-kappa B signaling pathway in systemic lupus erythematosus. MOLECULAR IMMUNOLOGY 56:643-648(2013).