ISG20

  • Official Full Name

    interferon stimulated exonuclease gene 20kDa

  • Overview

    Interferon-stimulated gene 20 kDa protein is a protein that in humans is encoded by the ISG20 gene.
  • Synonyms

    ISG20; interferon stimulated exonuclease gene 20kDa; interferon stimulated gene (20kD); interferon-stimulated gene 20 kDa protein; CD25; HEM45; Estrogen regulated transcript 45 protein; Interferon stimulated gene 20 kDa protein; Promyelocytic leukemia nuclear body associated protein; OTTHUMP00000192918; estrogen-regulated transcript 45 protein; promyelocytic leukemia nuclear body-associated protein ISG20;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Human Cells
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ISG20-28642TH Recombinant Human ISG20, His-tagged His
Human ISG20-5151HCL Recombinant Human ISG20 293 Cell Lysate HEK293 N/A
Human ISG20-508H Recombinant Human ISG20 protein, GST-tagged E. coli GST
Human ISG20-5018H Recombinant Human ISG20 Protein, GST-tagged Wheat Germ GST
Human ISG20-1065H Recombinant Human ISG20 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human ISG20-2600H Recombinant Human ISG20 protein, His-tagged E.coli His
Human ISG20-151H Recombinant Human ISG20 Protein, His-tagged Human Cells His
Human ISG20-1682HFL Recombinant Full Length Human ISG20 Protein, C-Flag-tagged Mammalian cells Flag
Human ISG20-5753HF Recombinant Full Length Human ISG20 Protein, GST-tagged In Vitro Cell Free System GST
Human ISG20-1204H-B Recombinant Human ISG20 Protein Pre-coupled Magnetic Beads HEK293
Human ISG20-1204H Recombinant Human ISG20 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Isg20-3584M Recombinant Mouse Isg20 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque ISG20-2307R Recombinant Rhesus monkey ISG20 Protein, His-tagged Mammalian Cell His
Rhesus Macaque ISG20-2128R Recombinant Rhesus Macaque ISG20 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque ISG20-2128R-B Recombinant Rhesus Macaque ISG20 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ISG20 Related Gene Family

ISG20 involved in several pathways and played different roles in them. We selected most pathways ISG20 participated on our site, such as Cytokine Signaling in Immune system, Immune System, Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with ISG20 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine Signaling in Immune systemSPNA1;DUSP10;ARIH1L;DUSP6;SPRED1;LAMTOR2;SPRED2;IRAK3;RASGRP4
Immune SystemSIGIRR;TRIM3;KIF3B;FCN2;FCN1;NLRP4B;LTF;ASB4;BAIAP2
Interferon SignalingEIF4G2A;IFIT3;TRIM31;TRIM8;TRIM62;GBP5;IFIT8;SAMHD1;TRIM6
Interferon alpha/beta signalingIFIT2;BST2;IFI35;IRF9;MX2;IFI6;USP18;IFITM2;XAF1

ISG20 has several biochemical functions, for example, 3-5-exoribonuclease activity, U1 snRNA binding, U2 snRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ISG20 itself. We selected most functions ISG20 had, and list some proteins which have the same functions with ISG20. You can find most of the proteins on our site.

Function Related Protein
3-5-exoribonuclease activityEXOSC4;DIS3L;DIS3;REXO2;ISG20;C16orf57;TOE1;EXOSC7;DIS3L2
U1 snRNA bindingSNRPA;SNRNP70;PRPF8;ISG20
U2 snRNA bindingISG20;PRPF8;SNRPA1;TROVE2
U3 snoRNA bindingNHP2L1;DIEXF;ISG20
exonuclease activityAEN;WRN;EXO5;LOC81691;CNOT6L;REXO1;EXO1;ISG20L2;FEN1
exoribonuclease II activity
metal ion bindingTHAP2;AMPD3;PRIM2;CYBB;GPHN;ACSM5;AMPD2;USP19;ZBTB12.1
single-stranded DNA 3-5 exodeoxyribonuclease activityMEIOB;DEM1;ISG20

ISG20 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ISG20 here. Most of them are supplied by our site. Hope this information will be useful for your research of ISG20.

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