• Official Full Name
  • leukocyte cell derived chemotaxin 1
  • Background
  • This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.
  • Synonyms
  • LECT1; leukocyte cell derived chemotaxin 1; multiple myeloma tumor suppressor 1 , MYETS1; leukocyte cell-derived chemotaxin 1; CHM I; CHM1; chondromodulin; Chondromodulin I; BRICD3; BRICHOS domain containing 3; Chondrosurfactant protein; LECT 1; chondromodulin-1; chondromodulin-I; OTTHUMP00000018466; OTTHUMP00000235443; multiple myeloma tumor suppressor 1; CHM-I; MYETS1
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human LECT1
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human leukocyte cell derived chemotaxin 1, His-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human LECT1, His-tagged
Source (Host):HEK293Species:Human
Product nameRecombinant Human LECT1 Protein, Fc-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse LECT1 Protein
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat LECT1 Protein
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken LECT1
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish LECT1
Source (Host):Species:Human
Product nameRecombinant Human LECT1 293 Cell Lysate

Interacting Protein

LECT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LECT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LECT1.

LECT1 Related Articles

Li, CH; Lu, XJ; et al. Passive protective effect of chicken egg yolk immunoglobulins against experimental Vibrio anguillarum infection in ayu (Plecoglossus altivelis). FISH & SHELLFISH IMMUNOLOGY 37:108-114(2014).
Okumura, A; Saito, T; et al. Suppressive role of leukocyte cell-derived chernotaxin 2 in mouse anti-type II collagen antibody-induced arthritis. ARTHRITIS AND RHEUMATISM 58:413-421(2008).