Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

LYN

  • Official Full Name

    v-yes-1 Yamaguchi sarcoma viral related oncogene homolog

  • Overview

    Lyn, one of the Src family members, is predominantly expressed in hematopoietic cells. Two tyrosine residues have been reported to play a crucial role in the regulation of protein tyrosine kinases of the Src family. Autophosphorylation of Tyr396 (equivale
  • Synonyms

    LYN; v-yes-1 Yamaguchi sarcoma viral related oncogene homolog; tyrosine-protein kinase Lyn; JTK8; lck/Yes-related novel protein tyrosine kinase; p53Lyn; p56Lyn; FLJ26625;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect (sf21)
  • Insect cell
  • Insect Cell
  • Mammalian Cell
  • Sf21
  • Sf9 Insect Cell
  • Wheat Germ
  • DDK
  • Flag
  • GST
  • GST|His
  • His
  • His (Fc)
  • Avi
  • Myc
  • Myc|DDK
  • N/A
  • N
  • FLAG
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LYN-252H Active Recombinant Human LYN Protein, GST-tagged Insect Cell GST
Human LYN-95HFL Active Recombinant Full Length Human LYN Protein, N-His-tagged Sf21 His Full Length
Human LYN-27984TH Recombinant Human LYN N/A
Human LYN-28760TH Recombinant Human LYN E.coli N/A
Human LYN-1254H Recombinant Human V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog, His-tagged Insect Cell N/A
Human LYN-7218H Recombinant Human LYN, His-tagged E.coli His 1-512aa
Human LYN-643H Recombinant Human LYN, GST-tagged E.coli GST
Human LYN-1127H Recombinant Human V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog, GST-tagged Sf9 Insect Cell GST
Human LYN-61H Recombinant Human LYN protein, Flag-tagged, Biotinylated Insect Cell Flag
Human LYN-656HCL Recombinant Human LYN cell lysate Insect Cell N/A
Human LYN-4556H Recombinant Human LYN Protein, GST-tagged Wheat Germ GST
Human LYN-4557H Active Recombinant Human LYN Protein, GST/His-tagged Insect Cell GST/His
Human LYNA-760H Active Recombinant Human LYNA Protein, His/GST-tagged Insect cell His&GST
Human LYN-9787HF Active Recombinant Full Length Human LYN Protein, DDK-tagged, Biotinylated Insect (sf21) DDK 1-512(end)
Human LYN-1343H Recombinant Human LYN Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human LYN-6237HF Recombinant Full Length Human LYN Protein, GST-tagged In Vitro Cell Free System GST 512 amino acids
Human LYN-3071HF Active Recombinant Full Length Human LYN Protein, GST-tagged Insect (sf21) GST 1-491(end)
Human LYN-4696HF Active Recombinant Full Length Human LYN Protein, GST-tagged Insect (sf21) GST 1-512(end)
Human LYN-514H Recombinant Human LYN Protein, His-tagged E.coli His Val263~Pro491
Human LYN-0766H Recombinant Human LYN Protein (K233-P512), Tag Free Insect Cell No tag K233-P512
Human LYN-2705H Recombinant Human LYN Protein (Met263-Asp491), His tagged E.coli His Met263-Asp491
Human LYN-0767H Recombinant Human LYN Protein (K233-P512), His tagged Insect Cell His K233-P512
Human LYN-4990H Recombinant Human LYN Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human LYN-12H Recombinant Human LYN Protein (Full Length), N-FLAG tagged Insect Cell N-FLAG Full Length
Mouse LYN-96MFL Active Recombinant Full Length Mouse LYN Protein, N-His-tagged Sf21 His Full Length
Mouse LYN-9386M Recombinant Mouse LYN Protein Mammalian Cell His
Mouse LYN-5263M-B Recombinant Mouse LYN Protein Pre-coupled Magnetic Beads HEK293
Mouse Lyn-3877M Recombinant Mouse Lyn Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Lyn-3194M Recombinant Mouse Lyn protein, His&Myc-tagged E.coli His&Myc 2-512aa
Mouse LYN-5263M Recombinant Mouse LYN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat LYN-3514R Recombinant Rat LYN Protein Mammalian Cell His
Rat LYN-3170R Recombinant Rat LYN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat LYN-3170R-B Recombinant Rat LYN Protein Pre-coupled Magnetic Beads HEK293
Zebrafish LYN-1267Z Recombinant Zebrafish LYN Mammalian Cell His
Chicken LYN-1532C Recombinant Chicken LYN Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • LYN Related Articles
  • LYN Related Research Area

LYN involved in several pathways and played different roles in them. We selected most pathways LYN participated on our site, such as Chemokine signaling pathway, NF-kappa B signaling pathway, Platelet activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with LYN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chemokine signaling pathwayPRKCB;GSK3B;CXCR1;PXN;CXCL16;AMCF-II;GSK3A;GM13306;PIK3CA
NF-kappa B signaling pathwayZAP70;GADD45B;LCK;TRAF1;RELA;GM13304;ERC1;TRAF6;MAP3K14
Platelet activationROCK1;NOS3;ITPR1;GNAS;ROCK2;ARHGAP35;PTGIR;TBXAS1;PPP1CA
B cell receptor signaling pathwayPPP3R2;SOS1;RAF1;DAPP1;IKBKG;PIK3R5;ITPR2;IGHM;DOK3
Fc epsilon RI signaling pathwayMAPK13;MAP2K1;GM-CSF;VAV3;HRAS;FYN;PIK3CB;GRB2;MAPK12
Fc gamma R-mediated phagocytosisASAP3;cgr2b;MARCKS;HCK;INPPL1;FCGR2B;DOCK2;VAV3;NCF1
Long-term depressionRAF1;PRKCG;NOS1;PPP1R17;PRKCB;PRKG2;GNAI2;PLA2G4C;GRM1
Epithelial cell signaling in Helicobacter pylori infectionIKBKB;GIT1;JAM3;ATP6V1D;F11R;CCL5;MAPK12;ATP6V1G3;MAP2K4
Epstein-Barr virus infectionYWHAE;MAP3K14;HSPA1L;SND1;HLA-DRB4;YWHAH;H2-Q10;SPN;HLA-B
Viral carcinogenesisIRF7;HDAC9;ATP6V0D1;HIST1H2BE;HDAC8;DLG1;IL6ST;RBL2;HIST1H2BF

LYN has several biochemical functions, for example, ATP binding, SH3 domain binding, enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LYN itself. We selected most functions LYN had, and list some proteins which have the same functions with LYN. You can find most of the proteins on our site.

Function Related Protein
ATP bindingABCC5;DAPK2;SYN2;CCT7;ATP2A1L;EEF2K;EPHB3;PSMC6;YARS2
SH3 domain bindingMYPN;REPS1;CABYR;EPS15;PLSCR1;ARHGAP31;FAM125A;CD2AP;OSTF1
enzyme bindingERN1;BLZF1;SCNM1-PS;HLCS;CCDC99;C6orf211;CREB1;APOA1;PPARG
gamma-tubulin bindingMARK4;LYN;SPATC1;NDRG1;RAB11FIP5;TUBGCP3;CEP57;DIXDC1;BLOC1S2A
glycosphingolipid bindingCel;LAMA1;Il2;LYN;SELP;SELL;LAMB1;LAMC1
integrin bindingS1PR2;ITGB1BP2;FBLN1;ANXA7;ILK;TSPAN8;COL16A1;ICAM1;COL3A1
ion channel bindingDLG1;CALM1;KCNQ3;TCAP;CALM3;KCNH1;KCNJ11;LYN;CIB1
non-membrane spanning protein tyrosine kinase activityLCK;PTK6B;BAZ1B;WEE2;JAK1;FER;STK16;JAK3;YRK
phosphoprotein bindingYWHAE;LRP11;FKBP4;RB1;PAFAH1B1;RRAGA;SFN;YWHAB;SAG
platelet-derived growth factor receptor bindingPDGFC;PDGFAA;PTPRJ;PDGFAB;TYMP;PDGFB;FIGF;PDGFA;PDGFRA
protein bindingGSTA4;NCOA2;BANF1;RALB;RAB22A;FRMD6;FCNA;CHGB;EHMT2
protein tyrosine kinase activityEPHA7;BAZ1B;EPHB2;TESK1;CSK;FGFR1B;IGF1R;TYRO3;PTK2
receptor bindingASIP;FGF12A;GNB2L1;TNFSF8;CADM1;HILPDA;GBA;PTK2;UCN2
receptor signaling protein tyrosine kinase activityKITA;KIT;LYN;ERBB4A;INSR;KITB;ERBB4;TYRO3;EGFR
ubiquitin protein ligase bindingIKBKE;RALB;MAGEA2;CUL4A;DNM1L;FAF2;SMAD7;Fzd4;UBE2G1B

LYN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LYN here. Most of them are supplied by our site. Hope this information will be useful for your research of LYN.

EGFR; polg_hcvh; polg_hcvco; KHDRBS1; polg_hcvj4; PTK2; tip_shv2c

Chang, CH; Wang, Y; et al. Extensive crosslinking of CD22 by epratuzumab triggers BCR signaling and caspase-dependent apoptosis in human lymphoma cells. MABS 7:199-211(2015).
Xiao, ZG; Sperl, B; et al. Metformin and salinomycin as the best combination for the eradication of NSCLC monolayer cells and their alveospheres (cancer stem cells) irrespective of EGFR, KRAS, EML4/ALK and LKB1 status. ONCOTARGET 5:12877-12890(2014).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All LYN Products

Required fields are marked with *

My Review for All LYN Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends