MAP3K9

  • Official Full Name

    mitogen-activated protein kinase kinase kinase 9

  • Overview

    Mixed-lineage kinases (MLKs) belong to the mitogen activated kinase kinase kinase (MAPKKK) family of dual-specificity protein kinases. While not particularly well conserved at the sequence level, MLK1, 2 and 3 share a conserved domain structure consisting
  • Synonyms

    MAP3K9; mitogen-activated protein kinase kinase kinase 9; MLK1; MEKK9; PRKE1; mixed lineage kinase 1 (tyr and ser/thr specificity);

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Human
  • Mouse
  • E.coli
  • HEK293
  • Insect Cell
  • Mammalian Cell
  • Sf21
  • Sf9 Insect Cell
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MAP3K9-152H Active Recombinant Human MAP3K9(134-414) Protein, N-His-tagged Sf21 His 134-414 aa
Human MAP3K9-1040H Recombinant Human Mitogen-Activated Protein Kinase Kinase Kinase 9, GST-Tagged Sf9 Insect Cell GST
Human MAP3K9-1262H Recombinant Human Mitogen-Activated Protein Kinase Kinase Kinase 9, GST-tagged Insect Cell GST
Human MAP3K9-3052H Recombinant Human MAP3K9 protein, His-tagged E.coli His 575-821 aa
Mouse MAP3K9-9519M Recombinant Mouse MAP3K9 Protein Mammalian Cell His
Mouse MAP3K9-5336M-B Recombinant Mouse MAP3K9 Protein Pre-coupled Magnetic Beads HEK293
Mouse MAP3K9-5336M Recombinant Mouse MAP3K9 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

MAP3K9 involved in several pathways and played different roles in them. We selected most pathways MAP3K9 participated on our site, such as Insulin Signaling, p38 MAPK Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAP3K9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Insulin SignalingSNAP25A;FLOT1;MAPK4;KIF5B;MYO1C;MAPK6;STXBP3;CAP1;MAP4K1
p38 MAPK Signaling PathwayMAP3K9;MAP3K10;GADD45G

MAP3K9 has several biochemical functions, for example, ATP binding, JUN kinase kinase kinase activity, MAP kinase kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MAP3K9 itself. We selected most functions MAP3K9 had, and list some proteins which have the same functions with MAP3K9. You can find most of the proteins on our site.

Function Related Protein
ATP bindingKSR1;FICD;ABCG5;XRCC6;MLH1;BMPR1BB;NSFB;BLK;CCT6B
JUN kinase kinase kinase activityMAP3K1;MAP3K9;MAP3K10;MAP3K11;ALPK2
MAP kinase kinase activityMAPK10;MAP2K3;MAP2K2B;MAPKAPK5;MAP2K1;MAP2K7;MAP2K6;MAP2K2;MAP3K9
protein bindingDUSP12;SP4;PER2;TXNDC16;KLRD1;RAB35;KCTD9;NRG1;CNO
protein homodimerization activityTHRA;CARS;RAP1GAP;HLCS;APOBEC3G;LHPP;GREM2;LDB1;NR4A2
protein serine/threonine kinase activityMAPK13;SLK;WNK2;PSKH2;PRKCA;CAMK2D;STK39;SRPK3;PRKCHB
protein tyrosine kinase activityBCR;PTK2AB;INSRA;CLK2;AXL;TTN;MUSK;ERBB3A;MET

MAP3K9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAP3K9 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAP3K9.

HSP90AB1; abl-tide

Research Area

Related articles

Sharaf, H; Matou-Nasri, S; et al. Advanced glycation endproducts increase proliferation, migration and invasion of the breast cancer cell line MDA-MB-231. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1852:429-441(2015).
Jeon, JH; Kim, YH; et al. Bacillus anthracis genomic DNA enhances lethal toxin-induced cytotoxicity through TNF-alpha production. BMC MICROBIOLOGY 14:-(2014).
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