MRPL23

  • Official Full Name

    mitochondrial ribosomal protein L23

  • Overview

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. The gene is biallelically expressed, despite its location within a region of imprinted genes on chromosome 11.
  • Synonyms

    MRPL23; mitochondrial ribosomal protein L23; RPL23L; 39S ribosomal protein L23, mitochondrial; L23MRP; L23 mitochondrial-related protein; L23mt; MRP-L23; Ribosomal protein L23-like; ribosomal protein related to L23 (mitochondrial); RPL23;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MRPL23-488H Recombinant Human MRPL23 Mammalian Cell His
Human MRPL23-991H Recombinant Human MRPL23, His-tagged E.coli His 1-153aa
Human MRPL23-4186HCL Recombinant Human MRPL23 293 Cell Lysate HEK293 N/A
Human MRPL23-5568H Recombinant Human MRPL23 Protein, GST-tagged Wheat Germ GST
Human MRPL23-6415HF Recombinant Full Length Human MRPL23 Protein, GST-tagged In Vitro Cell Free System GST 153 amino acids
Human MRPL23-3510H Recombinant Human MRPL23 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human MRPL23-3510H-B Recombinant Human MRPL23 Protein Pre-coupled Magnetic Beads HEK293
Rat MRPL23-3768R Recombinant Rat MRPL23 Protein Mammalian Cell His
Rat MRPL23-3427R Recombinant Rat MRPL23 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat MRPL23-3427R-B Recombinant Rat MRPL23 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque MRPL23-2840R Recombinant Rhesus monkey MRPL23 Protein, His-tagged Mammalian Cell His
Rhesus Macaque MRPL23-2660R Recombinant Rhesus Macaque MRPL23 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque MRPL23-2660R-B Recombinant Rhesus Macaque MRPL23 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish MRPL23-287Z Recombinant Zebrafish MRPL23 Mammalian Cell His
Chicken MRPL23-4265C Recombinant Chicken MRPL23 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

MRPL23 involved in several pathways and played different roles in them. We selected most pathways MRPL23 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL23 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RibosomeMRPL27;RPL35A;RPS27.1;RPL31;RPS14;MRPS2;RPL26L1;RPS26;MRPS21

MRPL23 has several biochemical functions, for example, RNA binding, nucleotide binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL23 itself. We selected most functions MRPL23 had, and list some proteins which have the same functions with MRPL23. You can find most of the proteins on our site.

Function Related Protein
RNA bindingZBP1;ATXN1A;MCTS2;NPM1;RPS5;EXOSC5;PABPC5;CWC22;EIF4E1B
nucleotide bindingATP13A3;HSP90AA1.1;THOC4;GNA12A;AKT3A;SYNCRIP;UBE2G1B;MAGI1;TYMS
protein bindingPLEC;NFU1;STAG3;RPS3;HIST3H3;C1orf35;SYT6;RPF1;HDLBP
structural constituent of ribosomeRPS28;RPL9;RPL5B;MRPL37;MRPL27;RPSA;RPS6;RPL5A;MRPL10

MRPL23 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL23 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL23.

PNMA1; 40038273; ATG12; C20orf24; USP44; NDUFAB1; ASB10; 2_aha_camp; JAK3; YBX1; Ccser2; MRPL50; MRPL9; Cd2ap

Research Area

Related articles

Kaur, J; Stuart, RA; et al. Truncation of the Mrp20 protein reveals new ribosome-assembly subcomplex in mitochondria. EMBO REPORTS 12:950-955(2011).
Haque, ME; Elmore, KB; et al. Properties of the C-terminal Tail of Human Mitochondrial Inner Membrane Protein Oxa1L and Its Interactions with Mammalian Mitochondrial Ribosomes. JOURNAL OF BIOLOGICAL CHEMISTRY 285:28353-28362(2010).
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