npffr2 Protein, neuropeptide FF receptor 2


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Official Full Name neuropeptide FF receptor 2
Background This gene encodes a member of a subfamily of G-protein-coupled neuropeptide receptors. This protein is activated by the neuropeptides A-18-amide (NPAF) and F-8-amide (NPFF) and may function in pain modulation and regulation of the opioid system. Alternative splicing results in multiple transcript variants.
Synonyms NPFFR2; neuropeptide FF receptor 2; G protein coupled receptor 74 , GPR74; neuropeptide FF 2; NPFF2; NPGPR; G protein coupled receptor 74; G protein coupled receptor HLWAR 77; G protein coupled receptor HLWAR77; G-protein coupled receptor 74; G-protein coupled receptor HLWAR77; GPR 74; GPR74; HLWAR 77; HLWAR77; Neuropeptide G protein coupled receptor; Neuropeptide G-protein coupled receptor; NPFF 2; NPFF R2; NPFF2_HUMAN; NPFFR 2; G protein-coupled receptor 74
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human NPFFR2-1209HCL Recombinant Human NPFFR2 cell lysate N/A
    Human NPFFR2-1341H Recombinant Human NPFFR2, His-tagged E.coli His
    Human NPFFR2-6025H Recombinant Human NPFFR2 Protein Wheat Germ N/A
    Mouse NPFFR2-10818M Recombinant Mouse NPFFR2 Protein Mammalian Cell His
    Rat NPFFR2-4041R Recombinant Rat NPFFR2 Protein Mammalian Cell His
    Chicken NPFFR2-3283C Recombinant Chicken NPFFR2 Mammalian Cell His

    npffr2 involved in several pathways and played different roles in them. We selected most pathways npffr2 participated on our site, such as Class A/1 (Rhodopsin-like receptors), G alpha (q) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with npffr2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Class A/1 (Rhodopsin-like receptors) CHRM1; DRD4; MLN; OPN1LW1; ADORA2A; CYSLTR1; CCR3; HCAR1-2; PROKR1; PYY
    G alpha (q) signalling events TAE1; TAC3; QRFPR; NPSR1; GPR4; TRPC6A; PROK2; PMCH; OPN4.1; MGLL
    GPCR downstream signaling ADRA2B; SST1.1; INSL5; RHOAE; PROKR1; RGS21; CHRM4; GPR4; PTH2; EDNRAB
    GPCR ligand binding EMR2; ZFPM2B; GNB5B; CYSLTR1; FPR-RS4; PTHLHA; NPS; SST; OXGR1A.3; CX3CR1
    GPCRs, Class A Rhodopsin-like CYSLTR1; CCBP2; OPN1SW; GPR85; OR10A5; PTGDR2; DRD3; GPR65; CNR1; CCR8
    Gastrin-CREB signalling pathway via PKC and MAPK PROK1; MLN; LTB4R; RASGRP2; OPN4B; QRFPR; FFAR3; PRKCHB; ARHGEF25; OPN4A
    Neuroactive ligand-receptor interaction GRIK3; EDNRB2; TSHB; CALCRLA; DRD4B; PTH1RA; HTR2C; S1PR3; CYSLTR2; GRIA3
    Orexin and neuropeptides FF and QRFP bind to their respective receptors NPFFR2; HCRT; QRFP; QRFPR; NPFF

    npffr2 has several biochemical functions, for example, G-protein coupled receptor activity, neuropeptide receptor activity, opioid receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by npffr2 itself. We selected most functions npffr2 had, and list some proteins which have the same functions with npffr2. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled receptor activity GPR132; OLFR488; GPR26; GRM8; GPR18; OR51D1; OR10J1; GPRC5BB; GHRHR2; OLFCS1
    neuropeptide receptor activity NPFFR2.1; NMUR1; KISS1R; SORCS1; HCRTR1; NPFFR1L1; PRLHR; SORCS3; KISS1RB; NPFFR1L2
    opioid receptor binding NPFFR2; NPFFR2.1
    peptide binding PPIB; Npepo; NPFFR2; CCKAR; ADNP; RPS6KB1; TPP1; H2-Q10; GNRHR4; CLTB

    npffr2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with npffr2 here. Most of them are supplied by our site. Hope this information will be useful for your research of npffr2.

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