P2RX2 Protein


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Official Full Name purinergic receptor P2X, ligand-gated ion channel, 2
Background The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2013]
Synonyms P2RX2; purinergic receptor P2X, ligand-gated ion channel, 2; P2X2; DFNA41; P2X purinoceptor 2; ATP receptor; P2X Receptor, subunit 2;
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human P2RX2-142H Recombinant Human P2RX2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human P2RX2-143H Recombinant Human P2RX2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human P2RX2-144H Recombinant Human P2RX2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human P2RX2-492H Recombinant Human P2RX2 Mammalian Cell His
    Rat P2RX2-4228R Recombinant Rat P2RX2 Protein Mammalian Cell His
    Zebrafish P2RX2-9887Z Recombinant Zebrafish P2RX2 Mammalian Cell His
    Human P2RX2-3501HCL Recombinant Human P2RX2 293 Cell Lysate HEK293 N/A
    Human P2RX2-5263H Recombinant Human P2RX2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse P2rx2-4635M Recombinant Mouse P2rx2 Protein, Myc/DDK-tagged HEK293T Myc/DDK

    P2RX2 involved in several pathways and played different roles in them. We selected most pathways P2RX2 participated on our site, such as Calcium signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with P2RX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Calcium signaling pathway CACNA1B; BDKRB2; HTR2B; CACNA1SB; CACNA1G; VDAC1; PHKA1; PPP3CCA; EDNRBA; HRH1
    Neuroactive ligand-receptor interaction GABRR3A; TAAR12J; DRD1A; NR3C1; EDNRB2; GRM6A; MCHR1; GRIK5; AVPR1B; CNR1

    P2RX2 has several biochemical functions, for example, ATP binding, cadmium ion binding, cobalt ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by P2RX2 itself. We selected most functions P2RX2 had, and list some proteins which have the same functions with P2RX2. You can find most of the proteins on our site.

    Function Related Protein
    cadmium ion binding NOS1; P2RX2; NOS3; SLC11A2; MT3
    cobalt ion binding BIRC5; SLC11A2; P2RX2; NUDT16; PML
    copper ion binding S100U; CP; F5; MOXD1; MOXD1L; ATP7A; CCS; SERPINB1A; LOXL3A; S100A5
    drug binding Alb; SMO; PYGM; PIGC; UGT1A7; DCK; PNP; DAAM2; CHRNB3; IL2RA
    extracellular ATP-gated cation channel activity P2RX1; P2RX3A; P2RX3; P2RX2; P2RX5; NNR; P2RX7; P2RX4; P2RX8; P2RX3B
    identical protein binding BAK1; IFI16; PNMA5; LCP1; CSK; NEFL; CLDN8; GOT1; DES; CLDN3
    ligand-gated ion channel activity CHRNA3; CHRNB2; Chrng; CLCA2; GABRB1; P2RX2; TRPA1A; ANXA6; CLCA5; TRPA1B
    mercury ion binding PARK7; P2RX2
    nickel cation binding SLC11A2; P2RX2; CAR3; CA3
    phosphatidylinositol binding SNX19A; PLD1; NOXO1A; TULP4; PIK3C2G; SNX7; SH3PXD2A; PLD2; TNFAIP8L3; SNX31
    purinergic nucleotide receptor activity P2RX6; P2RX3B; P2RX2; P2RX7; P2RX8; P2RX3; NNR; P2RX1; P2RX3A; P2RX4A
    zinc ion binding GATAD2A; BRPF3; MSRB2; MSL2A; MSL2B; ZNF385A; LRSAM1; RNF17; ARIH2; SETDB2

    P2RX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with P2RX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of P2RX2.

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