PRMT7
-
Official Full Name
protein arginine methyltransferase 7 -
Overview
Arginine methylation is an apparently irreversible protein modification catalyzed by arginine methyltransferases, such;as PMT7, using S-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated in signal;transduction, RNA transport, and RNA splicing (Miranda et al., 2004 (PubMed 15044439)). -
Synonyms
PRMT7;protein arginine methyltransferase 7;protein arginine N-methyltransferase 7;FLJ10640;KIAA1933;histone-arginine N-methyltransferase PRMT7;myelin basic protein-arginine N-methyltransferase;[Myelin basic protein]-arginine N-methyltransferase PRM
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Mouse
- Rat
- E.coli
- Sf9 Cells
- HEK293
- Mammalian Cells
- Insect Cells
- His
- Flag
- Non
- DDK
- Myc
- GST
- Avi
- Fc
Involved Pathway
PRMT7 involved in several pathways and played different roles in them. We selected most pathways PRMT7 participated on our site, such as Chromatin modifying enzymes,Chromatin organization,RMTs methylate histone arginines, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRMT7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Chromatin organization | BRMS1,TADA2B,SMYD2,SMARCC1B,KDM7AB,MTA3,EHMT2,WDR77,C20orf20,SAP130 |
| RMTs methylate histone arginines | SMARCD3,WDR77,SMARCD1,ARID2,ARID1A,PRMT6,SMARCB1,SMARCB1B,SMARCC1B,SMARCE1 |
| Chromatin modifying enzymes | SUZ12,GATAD2AB,SMYD2A,SMARCD3B,KDM5A,SMARCB1,AEBP2,SUZ12A,PHF21A,RUVBL2 |
Protein Function
PRMT7 has several biochemical functions, for example, S-adenosylmethionine-dependent methyltransferase activity,[myelin basic protein]-arginine N-methyltransferase activity,histone binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PRMT7 itself. We selected most functions PRMT7 had, and list some proteins which have the same functions with PRMT7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| histone methyltransferase activity (H4-R3 specific) | PRMT8,PRMT6,PRMT1,PRMT8B |
| protein-arginine omega-N monomethyltransferase activity | PRMT8B,PRMT8,PRMT6 |
| protein-arginine omega-N asymmetric methyltransferase activity | PRMT2,PRMT8,PRMT3,PRMT1,CARM1,PRMT6,PRMT8B |
| S-adenosylmethionine-dependent methyltransferase activity | RRP8,AS3MT,PRMT8,NOP2,TPMT.1,WBSCR27,C6orf211,METTL7A,COQ5,PRMT8B |
| histone-arginine N-methyltransferase activity | PRMT8,PRMT6,CARM1,PRMT2,PRMT3,PRMT5 |
| ribonucleoprotein complex binding | RNASEL,YBX2,PRPF6,PRPF31,TIMM50,PES1,SECISBP2,SRP54A,PQBP1,UHMK1 |
| protein-arginine omega-N symmetric methyltransferase activity | PRMT5 |
| histone binding | CTCFL,NFKBIL2,HIST1H4F,ATRX,HIST1H4A,CHD2,IPO7,HIST1H4M,HIST1H4L,ATAD2 |
Interacting Protein
PRMT7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRMT7 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRMT7.
PIK3CG;ZBTB24;MNDA;H3F3C;POT1;SSR3;GANAB;REPS2;ICE1
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