Recombinant Human PRMT7, His-tagged

Cat.No. : PRMT7-176H
Product Overview : Recombinant Human Protein Arginine N-Methyltransferase 7/PRMT7 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-Asp692) of Human PRMT7 fused with a polyhistidine tag at the C-terminus.
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Description : Protein Arginine N-Methyltransferase 7 (PRMT7) belongs to the protein arginine N-methyltransferase family and PRMT7 subfamily. Arginine methyltransferase plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s. It may also play a role in embryonic stem cell (ESC) pluripotency and mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro. PRMT7 exists as homodimer and heterodimer. PRMT7 can catalyze the formation of omega-NG-monomethylarginine in peptides.
Source : HEK293
Species : Human
Tag : His
AA Sequence : MKIFCSRANPTTGSVEWLEEDEHYD YHQEIARSSYADMLHDKDRNVKYYQ GIRAAVSRVKDRGQK ALVLDIGTGTGLLSMMAVTAGADFC YAIEVFKPMADAAVKIVEKNGFSDK IKVINKHSTEVTVGP EGDMPCRANILVTELFDTELIGEGA LPSYEHAHRHLVEENCEAVPHRATV YAQLVESGRMWSWNK LFPIHVQTSLGEQVIVPPVDVESCP GAPSVCDIQLNQVSPADFTVLSDVL PMFSIDFSKQVSSSA ACHSRRFEPLTSGRAQVVLSWWDIE MDPEGKIKCTMAPFWAHSDPEEMQW RDHWMQCVYFLPQEE PVVQGSALYLVAHHDDYCVWYSLQR TSPEKNERVRQMRPVCDCQAHLLWN RPRFGEINDQDRTDR YVQALRTVLKPDSVCLCVSDGSLLS VLAHHLGVEQVFTVESSAASHKLLR KIFKANHLEDKINII EKRPELLTNEDLQGRKVSLLLGEPF FTTSLLPWHNLYFWYVRTAVDQHLG PGAMVMPQAASLHAV VVEFRDLWRIRSPCGDCEGFDVHIM DDMIKRALDFRESREAEPHPLWEYP CRSLSEPWQILTFDF QQPVPLQPLCAEGTVELRRPGQSHA AVLWMEYHLTPECTLSTGLLEPADP EGGCCWNPHCKQAVY FFSPAPDPRALLGGPRTVSYAVEFH PDTGDIIMEFRHADTPDVDHHHHHH
Endotoxin : Less than 0.1 ng/μg (1 IEU/μg).
Purity : Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Publication :
Gene Name : PRMT7 protein arginine methyltransferase 7 [ Homo sapiens ]
Official Symbol : PRMT7
Synonyms : PRMT7; protein arginine methyltransferase 7; protein arginine N-methyltransferase 7; FLJ10640; KIAA1933; histone-arginine N-methyltransferase PRMT7; myelin basic protein-arginine N-methyltransferase; [Myelin basic protein]-arginine N-methyltransferase PRMT7;
Gene ID : 54496
mRNA Refseq : NM_001184824
Protein Refseq : NP_001171753
MIM : 610087
UniProt ID : Q9NVM4
Chromosome Location : 16q22.1
Function : S-adenosylmethionine-dependent methyltransferase activity; [myelin basic protein]-arginine N-methyltransferase activity; histone binding; histone methyltransferase activity (H4-R3 specific); histone-arginine N-methyltransferase activity; protein methyltransferase activity; protein-arginine omega-N monomethyltransferase activity; protein-arginine omega-N symmetric methyltransferase activity; protein-arginine omega-N symmetric methyltransferase activity; ribonucleoprotein complex binding; transferase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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